MATN1 and B4GALT2

		MATN1	B4GALT2
Description		matrilin 1	beta-1,4-galactosyltransferase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Matrix Matrilin Complex	Golgi Membrane Nucleoplasm Golgi Apparatus Membrane Golgi Cisterna Membrane
	Molecular Function	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding	Beta-N-acetylglucosaminylglycopeptide Beta-1,4-galactosyltransferase Activity N-acetyllactosamine Synthase Activity Lactose Synthase Activity Protein Binding Galactosyltransferase Activity Transferase Activity Glycosyltransferase Activity Metal Ion Binding
	Biological Process	Chondrocyte Differentiation Growth Plate Cartilage Chondrocyte Morphogenesis Extracellular Matrix Organization Regulation Of Bone Mineralization Protein-containing Complex Assembly	Carbohydrate Metabolic Process Protein Glycosylation Brain Development Memory Locomotory Behavior Visual Learning Cerebellar Purkinje Cell Layer Development Glycosylation
Pathways		ECM proteoglycans	Keratan sulfate biosynthesis N-Glycan antennae elongation
Drugs
Diseases
GWAS		Broad depression or schizophrenia ( 30626913) Low high density lipoprotein cholesterol levels ( 26879886) Monocyte count ( 32888494) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Schizophrenia ( 28991256 30285260) Serum alkaline phosphatase levels ( 33339817)	Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 30072576)
Interacting Genes		5 interacting genes: COL2A1 ITGA1 MATN2 MATN3 MATN4	3 interacting genes: GPR35 MEOX2 PFDN6
Entrez ID		4146	8704
HPRD ID		00276	04928
Ensembl ID		ENSG00000162510	ENSG00000117411
Uniprot IDs		P21941	O60909
PDB IDs
Enriched GO Terms of Interacting Partners?		Matrilin Complex Extracellular Matrix Organization Extracellular Structure Organization Extracellular Matrix Extracellular Matrix Structural Constituent Basement Membrane Cartilage Development Integrin Alpha1-beta1 Complex Dendrite Regeneration Calcium Ion Binding Collagen Type II Trimer Lactose Synthase Activity Collagen Type XI Trimer Skeletal System Development Anterior Head Development Collagen Binding Involved In Cell-matrix Adhesion N-acetyllactosamine Synthase Activity Beta-N-acetylglucosaminylglycopeptide Beta-1,4-galactosyltransferase Activity MHC Class II Protein Binding Phosphatase Activator Activity Galactosyltransferase Activity Otic Vesicle Development Extracellular Region Fibrillar Collagen Trimer Limb Bud Formation Notochord Development Platelet-derived Growth Factor Binding Cerebellar Purkinje Cell Layer Development Embryonic Skeletal Joint Morphogenesis Endoplasmic Reticulum Lumen Proteoglycan Binding Basal Part Of Cell Cellular Extravasation Cartilage Condensation Cartilage Development Involved In Endochondral Bone Morphogenesis	Contractile Muscle Fiber
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