MATN1 and MATN4

Number of citations of the paper that reports this interaction (PubMedID 11896063)
0

Data Source:
HPRD (in vitro)

		MATN1	MATN4
Description		matrilin 1	matrilin 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Matrix Matrilin Complex	Extracellular Region Extracellular Matrix Matrilin Complex
	Molecular Function	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding	Calcium Ion Binding Protein Binding
	Biological Process	Chondrocyte Differentiation Growth Plate Cartilage Chondrocyte Morphogenesis Extracellular Matrix Organization Regulation Of Bone Mineralization Protein-containing Complex Assembly	Extracellular Matrix Organization
Pathways		ECM proteoglycans	ECM proteoglycans
Drugs
Diseases
GWAS		Broad depression or schizophrenia ( 30626913) Low high density lipoprotein cholesterol levels ( 26879886) Monocyte count ( 32888494) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Schizophrenia ( 28991256 30285260) Serum alkaline phosphatase levels ( 33339817)	Blood protein levels ( 30072576) Malaria ( 31844061)
Interacting Genes		5 interacting genes: COL2A1 ITGA1 MATN2 MATN3 MATN4	9 interacting genes: ACSF3 ENKD1 GORASP2 MATN1 MATN2 MATN3 NTAQ1 PPP1R13B SDCBP
Entrez ID		4146	8785
HPRD ID		00276	04873
Ensembl ID		ENSG00000162510	ENSG00000124159
Uniprot IDs		P21941	A2RRP8 A5D8U1 A6NNA4 B3KQB2 O95460
PDB IDs
Enriched GO Terms of Interacting Partners?		Matrilin Complex Extracellular Matrix Organization Extracellular Structure Organization Extracellular Matrix Extracellular Matrix Structural Constituent Basement Membrane Cartilage Development Integrin Alpha1-beta1 Complex Dendrite Regeneration Calcium Ion Binding Collagen Type II Trimer Lactose Synthase Activity Collagen Type XI Trimer Skeletal System Development Anterior Head Development Collagen Binding Involved In Cell-matrix Adhesion N-acetyllactosamine Synthase Activity Beta-N-acetylglucosaminylglycopeptide Beta-1,4-galactosyltransferase Activity MHC Class II Protein Binding Phosphatase Activator Activity Galactosyltransferase Activity Otic Vesicle Development Extracellular Region Fibrillar Collagen Trimer Limb Bud Formation Notochord Development Platelet-derived Growth Factor Binding Cerebellar Purkinje Cell Layer Development Embryonic Skeletal Joint Morphogenesis Endoplasmic Reticulum Lumen Proteoglycan Binding Basal Part Of Cell Cellular Extravasation Cartilage Condensation Cartilage Development Involved In Endochondral Bone Morphogenesis	Matrilin Complex Extracellular Matrix Structural Constituent Extracellular Structure Organization Growth Plate Cartilage Chondrocyte Morphogenesis Extracellular Matrix Organization Interleukin-5 Receptor Complex Protein-N-terminal Glutamine Amidohydrolase Activity Malonyl-CoA Synthetase Activity Malonate Catabolic Process Extracellular Matrix Dendrite Regeneration Interleukin-5 Receptor Binding Protein-N-terminal Asparagine Amidohydrolase Activity Positive Regulation Of Extracellular Exosome Assembly Syndecan Binding
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