MIR205 and SYNCRIP

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR205	SYNCRIP
Description		microRNA 205	synaptotagmin binding cytoplasmic RNA interacting protein
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space RISC Complex	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Endoplasmic Reticulum Cytosol Membrane MRNA Editing Complex CRD-mediated MRNA Stability Complex Catalytic Step 2 Spliceosome Histone Pre-mRNA 3'end Processing Complex GAIT Complex MCRD-mediated MRNA Stability Complex Ribonucleoprotein Complex
	Molecular Function	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity	Nucleic Acid Binding RNA Binding Protein Binding MRNA 5'-UTR Binding
	Biological Process	Negative Regulation Of Endothelial Cell Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Angiogenesis Negative Regulation Of Cell Migration MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Receptor-mediated Endocytosis Negative Regulation Of Inflammatory Response Negative Regulation Of SMAD Protein Signal Transduction Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Extracellular Matrix Disassembly Negative Regulation Of Fibroblast Growth Factor Production Regulation Of Aorta Morphogenesis Negative Regulation Of Vascular Endothelial Growth Factor Production	MRNA Splicing, Via Spliceosome Osteoblast Differentiation RNA Processing MRNA Processing Regulation Of Translation RNA Splicing MRNA Modification Negative Regulation Of Translation CRD-mediated MRNA Stabilization Cellular Response To Type II Interferon Chromosomal 5-methylcytosine DNA Demethylation Pathway Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Positive Regulation Of Cytoplasmic Translation
Pathways
Drugs
Diseases
GWAS
Interacting Genes		92 interacting genes: AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CELF1 CELF2 CPSF1 DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EDC4 EIF2AK2 EPRS1 FAM98A FAM98B FIP1L1 FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT21 NUFIP2 PDCD11 PGAM5 PLRG1 PTBP1 PTBP3 PTCD3 PUF60 PURA QARS1 RARS1 RBFOX2 RBM14 RBM4 RBM45 RBMS1 RBMS2 RTCA RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SUGP2 SYNCRIP TAF15 TRA2A TRA2B TRIM25 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZC3H7B ZNF346	111 interacting genes: A1CF APOBEC1 APP CEBPA CIP2A CSDE1 EPRS1 ESR1 FNDC3B GRB2 HABP4 HMGA1 HMGA2 HNRNPD HNRNPK IL7R INSR IVNS1ABP KLHL3 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MYPOP NUPR1 OGT PABPC1 PCSK7 PLCG1 PRMT1 PTPN11 SMN1 SUMO2 SYT1 SYT11 SYT2 SYT3 SYT4 SYT7 SYT8 SYT9 TRIM55 TRIM63
Entrez ID		406988	10492
HPRD ID			06734
Ensembl ID		ENSG00000284485	ENSG00000135316
Uniprot IDs			A0A7I2V309 A0A7I2YQN2 B7Z645 O60506 Q59GL1
PDB IDs			2DGU 2MXT 2NBB 6KOR
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process Nucleic Acid Metabolic Process RNA Splicing MRNA Metabolic Process MRNA Processing Nucleobase-containing Compound Metabolic Process MRNA Binding Macromolecule Metabolic Process Regulation Of RNA Splicing Ribonucleoprotein Complex Nucleus Regulation Of MRNA Metabolic Process Aminoacyl-tRNA Synthetase Multienzyme Complex Nucleoplasm MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Post-transcriptional Regulation Of Gene Expression Cytoplasmic Stress Granule Spliceosomal Complex MRNA 3'-UTR Binding Regulation Of MRNA Processing Catalytic Step 2 Spliceosome Regulation Of MRNA Splicing, Via Spliceosome MiRNA Binding Regulation Of Translation Negative Regulation Of MRNA Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Catabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Catabolic Process RNA Stabilization Negative Regulation Of Translation TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity TRNA Metabolic Process Regulation Of Macromolecule Metabolic Process TRNA Aminoacylation Ligase Activity MRNA Stabilization Regulation Of RNA Stability Pre-mRNA Binding Positive Regulation Of Cytoplasmic Translation Regulation Of MRNA Stability Positive Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Primary Metabolic Process	MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation MiRNA-mediated Gene Silencing By MRNA Destabilization Extracellular Vesicle Negative Regulation Of Translation Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process MRNA Destabilization Positive Regulation Of MRNA Catabolic Process Regulation Of Translation RNA Destabilization Regulation Of Macromolecule Metabolic Process Positive Regulation Of MRNA Metabolic Process Regulation Of MRNA Stability Regulation Of Metabolic Process Negative Regulation Of Cytokine Production Regulation Of RNA Stability Regulation Of Angiogenesis Negative Regulation Of Cell Migration Regulation Of Vasculature Development Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Cell Motility Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Locomotion Regulation Of MRNA Metabolic Process Negative Regulation Of Developmental Process Negative Regulation Of Protein Metabolic Process Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Anatomical Structure Morphogenesis Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Endothelial Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Signaling Negative Regulation Of Cell Communication Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Cell Migration
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