MIR205 and RTCA

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR205	RTCA
Description		microRNA 205	RNA 3'-terminal phosphate cyclase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space RISC Complex	Nucleus Nucleoplasm
	Molecular Function	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity	Nucleotide Binding RNA Binding Catalytic Activity RNA-3'-phosphate Cyclase Activity Protein Binding ATP Binding Ligase Activity
	Biological Process	Negative Regulation Of Endothelial Cell Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Angiogenesis Negative Regulation Of Cell Migration MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Receptor-mediated Endocytosis Negative Regulation Of Inflammatory Response Negative Regulation Of SMAD Protein Signal Transduction Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Extracellular Matrix Disassembly Negative Regulation Of Fibroblast Growth Factor Production Regulation Of Aorta Morphogenesis Negative Regulation Of Vascular Endothelial Growth Factor Production	RNA Processing Negative Regulation Of Optical Nerve Axon Regeneration
Pathways
Drugs
Diseases
GWAS
Interacting Genes		92 interacting genes: AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CELF1 CELF2 CPSF1 DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EDC4 EIF2AK2 EPRS1 FAM98A FAM98B FIP1L1 FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT21 NUFIP2 PDCD11 PGAM5 PLRG1 PTBP1 PTBP3 PTCD3 PUF60 PURA QARS1 RARS1 RBFOX2 RBM14 RBM4 RBM45 RBMS1 RBMS2 RTCA RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SUGP2 SYNCRIP TAF15 TRA2A TRA2B TRIM25 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZC3H7B ZNF346	49 interacting genes: MIR1-1 MIR106B MIR10B MIR122 MIR128-1 MIR128-2 MIR138-2 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR199A1 MIR199A2 MIR19B2 MIR200A MIR205 MIR20B MIR21 MIR214 MIR222 MIR25 MIR29B2 MIR29C MIR31 MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR9-1 MIR9-2 MIR92A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NEIL3 OTX2
Entrez ID		406988	8634
HPRD ID			15280
Ensembl ID		ENSG00000284485	ENSG00000137996
Uniprot IDs			O00442
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process Nucleic Acid Metabolic Process RNA Splicing MRNA Metabolic Process MRNA Processing Nucleobase-containing Compound Metabolic Process MRNA Binding Macromolecule Metabolic Process Regulation Of RNA Splicing Ribonucleoprotein Complex Nucleus Regulation Of MRNA Metabolic Process Aminoacyl-tRNA Synthetase Multienzyme Complex Nucleoplasm MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Post-transcriptional Regulation Of Gene Expression Cytoplasmic Stress Granule Spliceosomal Complex MRNA 3'-UTR Binding Regulation Of MRNA Processing Catalytic Step 2 Spliceosome Regulation Of MRNA Splicing, Via Spliceosome MiRNA Binding Regulation Of Translation Negative Regulation Of MRNA Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Catabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Catabolic Process RNA Stabilization Negative Regulation Of Translation TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity TRNA Metabolic Process Regulation Of Macromolecule Metabolic Process TRNA Aminoacylation Ligase Activity MRNA Stabilization Regulation Of RNA Stability Pre-mRNA Binding Positive Regulation Of Cytoplasmic Translation Regulation Of MRNA Stability Positive Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Primary Metabolic Process	MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Regulation Of Angiogenesis Regulation Of Vasculature Development Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Extracellular Vesicle Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Negative Regulation Of Translation Regulation Of Macromolecule Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Metabolic Process Regulation Of Anatomical Structure Morphogenesis Extracellular Space Negative Regulation Of Cytokine Production Positive Regulation Of Connective Tissue Replacement Negative Regulation Of Cell Migration Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Tissue Remodeling Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Translation Negative Regulation Of Cell Motility Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Locomotion MRNA Destabilization Negative Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Connective Tissue Replacement Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis RNA Destabilization Regulation Of Endothelial Cell Migration Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Protein Metabolic Process Negative Regulation Of Developmental Process Regulation Of Cell Migration Regulation Of Multicellular Organismal Development Regulation Of Cell Motility Positive Regulation Of MRNA Metabolic Process
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