MIR205 and RBMS1

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR205	RBMS1
Description		microRNA 205	RNA binding motif single stranded interacting protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space RISC Complex	Nucleus Cytosol Ribonucleoprotein Complex
	Molecular Function	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity	Nucleic Acid Binding DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Poly(A) Binding Poly(U) RNA Binding
	Biological Process	Negative Regulation Of Endothelial Cell Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Angiogenesis Negative Regulation Of Cell Migration MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Receptor-mediated Endocytosis Negative Regulation Of Inflammatory Response Negative Regulation Of SMAD Protein Signal Transduction Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Extracellular Matrix Disassembly Negative Regulation Of Fibroblast Growth Factor Production Regulation Of Aorta Morphogenesis Negative Regulation Of Vascular Endothelial Growth Factor Production	DNA Replication RNA Processing
Pathways
Drugs
Diseases
GWAS			A body shape index ( 34021172) Adult body size ( 32376654) Age at first sexual intercourse ( 34211149) Amyotrophic lateral sclerosis ( 19451621) Basal cell carcinoma ( 31174203) Body size at age 10 ( 32376654) Chronotype ( 30696823) FEV1 ( 30804560) Gut microbiota relative abundance (Ruminococcus belonging to family Lachnospiraceae) ( 33208821) HDL cholesterol levels ( 32203549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference adjusted for BMI ( 34021172) Idiopathic membranous nephropathy ( 21323541) Intelligence (MTAG) ( 29326435) Lung function (FVC) ( 30804560) Lymphocyte count ( 27863252 32888494) Lymphocyte percentage of white cells ( 27863252 32888494) Monocyte percentage of white cells ( 27863252 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Peak expiratory flow ( 30804560) Refractive error ( 32231278) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Systolic blood pressure ( 30224653) Tourette syndrome ( 30818990) Triglyceride levels ( 32203549) Type 2 diabetes ( 20418489 30297969 30054458 29358691 22885922) Waist circumference adjusted for body mass index ( 34021172) Weight ( 31647587 28552196) White blood cell count ( 32888494 27863252)
Interacting Genes		92 interacting genes: AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CELF1 CELF2 CPSF1 DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EDC4 EIF2AK2 EPRS1 FAM98A FAM98B FIP1L1 FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT21 NUFIP2 PDCD11 PGAM5 PLRG1 PTBP1 PTBP3 PTCD3 PUF60 PURA QARS1 RARS1 RBFOX2 RBM14 RBM4 RBM45 RBMS1 RBMS2 RTCA RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SUGP2 SYNCRIP TAF15 TRA2A TRA2B TRIM25 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZC3H7B ZNF346	10 interacting genes: MIR16-2 MIR205 MIR29A MIR7-1 MIR92A2 MIR93 MIRLET7G OGT POLA1 TFCP2
Entrez ID		406988	5937
HPRD ID			03814
Ensembl ID		ENSG00000284485	ENSG00000153250
Uniprot IDs			A0A0S2Z499 P29558
PDB IDs			1X5O 6M75 7C36
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process Nucleic Acid Metabolic Process RNA Splicing MRNA Metabolic Process MRNA Processing Nucleobase-containing Compound Metabolic Process MRNA Binding Macromolecule Metabolic Process Regulation Of RNA Splicing Ribonucleoprotein Complex Nucleus Regulation Of MRNA Metabolic Process Aminoacyl-tRNA Synthetase Multienzyme Complex Nucleoplasm MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Post-transcriptional Regulation Of Gene Expression Cytoplasmic Stress Granule Spliceosomal Complex MRNA 3'-UTR Binding Regulation Of MRNA Processing Catalytic Step 2 Spliceosome Regulation Of MRNA Splicing, Via Spliceosome MiRNA Binding Regulation Of Translation Negative Regulation Of MRNA Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Catabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Catabolic Process RNA Stabilization Negative Regulation Of Translation TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity TRNA Metabolic Process Regulation Of Macromolecule Metabolic Process TRNA Aminoacylation Ligase Activity MRNA Stabilization Regulation Of RNA Stability Pre-mRNA Binding Positive Regulation Of Cytoplasmic Translation Regulation Of MRNA Stability Positive Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Primary Metabolic Process	RISC Complex MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA Base-pairing Post-transcriptional Repressor Activity Negative Regulation Of Cell Migration Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Metabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Vascular Endothelial Growth Factor Production MRNA 3'-UTR Binding Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cell Migration Negative Regulation Of SMAD Protein Signal Transduction Negative Regulation Of Translation Regulation Of Cell Motility Regulation Of Locomotion Regulation Of Vascular Endothelial Growth Factor Production MiRNA-mediated Gene Silencing By Inhibition Of Translation Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Cellular Response To Glucose Stimulus Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Signal Transduction Regulation Of SMAD Protein Signal Transduction Regulation Of Angiogenesis Regulation Of Vasculature Development Regulation Of Cellular Response To Growth Factor Stimulus Cellular Response To Carbohydrate Stimulus Extracellular Space Negative Regulation Of Cell Communication Negative Regulation Of Signaling Intracellular Glucose Homeostasis Extracellular Vesicle Negative Regulation Of Developmental Process Regulation Of Translation Lagging Strand Elongation
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