MIR205 and ZC3H7B

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR205	ZC3H7B
Description		microRNA 205	zinc finger CCCH-type containing 7B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space RISC Complex	Nucleus
	Molecular Function	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity	RNA Binding Protein Binding Zinc Ion Binding MiRNA Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Endothelial Cell Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Angiogenesis Negative Regulation Of Cell Migration MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Receptor-mediated Endocytosis Negative Regulation Of Inflammatory Response Negative Regulation Of SMAD Protein Signal Transduction Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Extracellular Matrix Disassembly Negative Regulation Of Fibroblast Growth Factor Production Regulation Of Aorta Morphogenesis Negative Regulation Of Vascular Endothelial Growth Factor Production	Post-transcriptional Regulation Of Gene Expression MiRNA Processing
Pathways
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Body size at age 10 ( 32376654) Caffeine consumption from tea ( 33287642) Eosinophil count ( 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252 32888494) General factor of neuroticism ( 30867560) Lamb consumption ( 32066663) Lymphocyte count ( 32888494) Meat-related diet ( 32066663) Medication use (thyroid preparations) ( 31015401) Neuroticism ( 29255261) Neutrophil percentage of granulocytes ( 27863252) Refractive error ( 32231278) Schizophrenia ( 29483656 28991256) Smoking cessation ( 33082346) Sum eosinophil basophil counts ( 27863252) Vitiligo ( 27723757) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		92 interacting genes: AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CELF1 CELF2 CPSF1 DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EDC4 EIF2AK2 EPRS1 FAM98A FAM98B FIP1L1 FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT21 NUFIP2 PDCD11 PGAM5 PLRG1 PTBP1 PTBP3 PTCD3 PUF60 PURA QARS1 RARS1 RBFOX2 RBM14 RBM4 RBM45 RBMS1 RBMS2 RTCA RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SUGP2 SYNCRIP TAF15 TRA2A TRA2B TRIM25 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZC3H7B ZNF346	6 interacting genes: ATXN1 ATXN1L MIR16-2 MIR205 MIR29A MIR7-1
Entrez ID		406988	23264
HPRD ID			06711
Ensembl ID		ENSG00000284485	ENSG00000100403
Uniprot IDs			Q9UGR2
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process Nucleic Acid Metabolic Process RNA Splicing MRNA Metabolic Process MRNA Processing Nucleobase-containing Compound Metabolic Process MRNA Binding Macromolecule Metabolic Process Regulation Of RNA Splicing Ribonucleoprotein Complex Nucleus Regulation Of MRNA Metabolic Process Aminoacyl-tRNA Synthetase Multienzyme Complex Nucleoplasm MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Post-transcriptional Regulation Of Gene Expression Cytoplasmic Stress Granule Spliceosomal Complex MRNA 3'-UTR Binding Regulation Of MRNA Processing Catalytic Step 2 Spliceosome Regulation Of MRNA Splicing, Via Spliceosome MiRNA Binding Regulation Of Translation Negative Regulation Of MRNA Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Catabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Catabolic Process RNA Stabilization Negative Regulation Of Translation TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity TRNA Metabolic Process Regulation Of Macromolecule Metabolic Process TRNA Aminoacylation Ligase Activity MRNA Stabilization Regulation Of RNA Stability Pre-mRNA Binding Positive Regulation Of Cytoplasmic Translation Regulation Of MRNA Stability Positive Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Primary Metabolic Process	RISC Complex MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing POZ Domain Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Lung Alveolus Development Social Behavior MiRNA-mediated Gene Silencing By Inhibition Of Translation MRNA Base-pairing Post-transcriptional Repressor Activity FMN Transmembrane Transporter Activity FAD Transmembrane Transporter Activity FAD Transmembrane Transport Negative Regulation Of Gene Expression AMP Transport AMP Transmembrane Transporter Activity Memory Coenzyme A Transmembrane Transport Coenzyme A Transmembrane Transporter Activity NAD Transmembrane Transport ADP Transmembrane Transporter Activity NAD Transmembrane Transporter Activity Negative Regulation Of Vasculature Development MRNA 3'-UTR Binding Negative Regulation Of Angiogenesis Negative Regulation Of Circulating Fibrinogen Levels Adenine Nucleotide Transmembrane Transporter Activity NAD Transport Regulation Of Aorta Morphogenesis Negative Regulation Of Fibroblast Growth Factor Production Regulation Of Endothelial Cell Proliferation Learning Regulation Of Gene Expression Regulation Of Cell Population Proliferation Negative Regulation Of Translation Regulation Of Macromolecule Biosynthetic Process Regulation Of Endothelial Cell Migration Fatty Acid Alpha-oxidation Poly(G) Binding ATP Transmembrane Transporter Activity Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Positive Regulation Of Hematopoietic Stem Cell Proliferation Regulation Of Artery Morphogenesis Brain Development Positive Regulation Of Extracellular Matrix Disassembly
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