LIFR and PTPN11

  • Number of citations of the paper that reports this interaction (PMID 10800945)
  • 2
  • Data Source:
  • HPRD (in vivo, in vitro)

LIFR

PTPN11

Gene Name leukemia inhibitory factor receptor alpha protein tyrosine phosphatase, non-receptor type 11
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 12 interactors: CNTF CNTFR CTF1 IL31RA IL6ST LIF MAPK1 OSM PLCG1 POU2F1 PTPN11 PTPN6 114 interactors: ACTN4 ARHGAP1 AXL BCR BDKRB2 BTLA C6orf25 CAT CAV1 CBL CCKBR CD33 CDH5 CEACAM1 CHUK CRKL CSF2RB CSF3R CTLA4 CXCR4 DAB1 DDR1 EGFR EPHA2 EPOR ERBB2 FCRL3 FLT1 FLT4 FRS2 FRS3 FYN GAB1 GAB2 GAB3 GHR GRB2 GRIN2B HNRNPU IFNAR1 IFNGR1 IGF1R IL4R IL6ST INPP5D INSR IRS1 IRS2 IRS4 JAK1 JAK2 KDR KIR2DL5A KIT KLRC1 LAIR1 LCK LEPR LIFR LILRB4 MAP3K4 MAP3K5 MAPK3 MET MPL MPZL1 MS4A2 MVP NEDD9 NTRK1 NTRK2 PAG1 PDGFRA PDGFRB PECAM1 PIK3CG PIK3R1 PILRA PILRB PLCG1 PRKCA PRKCB PRKCH PRLR PTK2 PTK2B PTPN6 PXN RET ROS1 RPIA SELE SHC1 SIGLEC11 SIGLEC12 SIGLEC7 SIRPA SIT1 SLAMF1 SLAMF6 SOCS3 SOS1 SPRY2 SRC STAT1 STAT3 STAT5A STAT5B SYNCRIP TEK TIE1 TNFRSF1A TREML1 TRIM32
Entrez ID 3977 5781
HPRD ID 01048 01470
Ensembl ID ENSG00000113594 ENSG00000179295
Uniprot IDs A8K1Z4 P42702 Q06124
PDB IDs 3E0G 2SHP 3B7O 3MOW 3O5X 3TKZ 3TL0 4DGP 4DGX 4GWF 4H1O 4H34 4JE4
Enriched GO Terms of Interacting Partners?
Tagcloud ?
box  chimeric  coexpression  consensus  constructs  contained  converges  dominant  entire  gp130  jak  lacking  mapk  maximal  maximally  mitogen  motif  polypeptide  polypeptides  positions  putative  ras  shp2  similarly  stimulate  stimulation  tyk  tyr  y118f 
absolute  case  cases  count  died  eleven  female  indispensable  interval  jmml  juvenile  male  median  monocytes  mutation  myelomonocytic  observation  obviously  onset  peripheral  platelet  plt  progressive  ras  retrospectively  slow  sure  wbc  white 
Tagcloud (Difference) ?
box  chimeric  coexpression  consensus  constructs  contained  converges  dominant  entire  gp130  jak  lacking  mapk  maximal  maximally  mitogen  motif  polypeptide  polypeptides  positions  putative  shp2  similarly  stimulate  stimulation  tyk  tyr  y118f 
absolute  case  cases  count  died  eleven  female  indispensable  interval  jmml  juvenile  male  median  monocytes  mutation  myelomonocytic  observation  obviously  onset  peripheral  platelet  plt  progressive  retrospectively  slow  sure  wbc  white 
Tagcloud (Intersection) ?
ras