LBR and AKAP8L

Number of citations of the paper that reports this interaction (PMID 11034899)
17

Data Source:
HPRD (in vivo)

		LBR	AKAP8L
Gene Name		lamin B receptor	A kinase (PRKA) anchor protein 8-like
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Envelope Integral Component Of Nuclear Inner Membrane Membrane Integral Component Of Membrane Nuclear Membrane	Nucleus Nucleoplasm Cytoplasm Nuclear Matrix
	Molecular Function	DNA Binding Protein Binding Lamin Binding Oxidoreductase Activity, Acting On The CH-CH Group Of Donors, NAD Or NADP As Acceptor Poly(A) RNA Binding Chromo Shadow Domain Binding	DNA Binding Protein Binding DEAD/H-box RNA Helicase Binding Poly(A) RNA Binding Metal Ion Binding
	Biological Process	Cholesterol Biosynthetic Process Small Molecule Metabolic Process Oxidation-reduction Process	Biological_process
Pathways		Cholesterol biosynthesis Metabolism of lipids and lipoproteins
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: AKAP8L CBX3 CBX5 FNBP4 HIST1H3A HIST2H4A LMNB1 MECP2 PRM1 SRPK1 YWHAG	7 interactors: CDC6 DHX9 EMD LBR PRKACA PRPF40A TMPO
Entrez ID		3930	26993
HPRD ID		02488	10641
Ensembl ID		ENSG00000143815	ENSG00000011243
Uniprot IDs		Q14739	Q9ULX6
PDB IDs		2DIG
Enriched GO Terms of Interacting Partners?		Chromatin Silencing DNA Packaging Chromosome Organization Negative Regulation Of Gene Expression, Epigenetic DNA Conformation Change Chromatin Organization DNA Replication-dependent Nucleosome Assembly Gene Silencing DNA Methylation On Cytosine Chromatin Silencing At RDNA Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Organelle Organization Negative Regulation Of Cellular Metabolic Process Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process DNA Methylation Methylation DNA Modification DNA Metabolic Process Nucleosome Assembly Histone H4-K20 Demethylation Chromatin Assembly Nucleosome Organization Catecholamine Secretion Chromatin Modification Chromatin Assembly Or Disassembly Negative Regulation Of Megakaryocyte Differentiation Proprioception Protein-DNA Complex Assembly Regulation Of Synaptic Plasticity Chromatin Remodeling Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Sperm Chromatin Condensation Regulation Of RNA Metabolic Process Cardiolipin Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Respiratory Gaseous Exchange By Neurological System Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Neuromuscular Process Controlling Posture Regulation Of Synaptic Transmission Regulation Of Respiratory System Process Regulation Of Gene Expression Glucocorticoid Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process	Positive Regulation Of Protein Export From Nucleus Regulation Of Protein Export From Nucleus Mitotic Nuclear Envelope Disassembly Nuclear Envelope Disassembly Regulation Of Cytokinesis Nuclear Envelope Organization Regulation Of Cell Cycle Process Positive Regulation Of Dense Core Granule Biogenesis Cell Cycle Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Mitotic Cell Cycle Nucleus Organization Histone H3-T6 Phosphorylation Organelle Organization Negative Regulation Of Cell Proliferation Mitotic Cell Cycle Process Positive Regulation Of Intracellular Protein Transport Mitotic Cell Cycle Traversing Start Control Point Of Mitotic Cell Cycle CRD-mediated MRNA Stabilization Regulation Of Proteasomal Protein Catabolic Process Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Cell Cycle Process Regulation Of Cell Cycle Peptidyl-serine Autophosphorylation Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Cellular Response To Parathyroid Hormone Stimulus Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Positive Regulation Of Intracellular Transport Regulation Of Cell Division Mitotic Cell Cycle Phase Transition Regulation Of Intracellular Protein Transport Cell Cycle Phase Transition Cell Cycle Process Desmosome Assembly Mitotic Nuclear Envelope Reassembly Negative Regulation Of Glial Cell Apoptotic Process Positive Regulation Of Cell Cycle Regulation Of Tight Junction Assembly DNA Replication Checkpoint Negative Regulation Of Catenin Import Into Nucleus Negative Regulation Of Glucose Import Positive Regulation Of Macrophage Differentiation Nuclear Envelope Reassembly Cell Communication By Electrical Coupling Involved In Cardiac Conduction Calcium-mediated Signaling Using Intracellular Calcium Source Desmosome Organization Response To Parathyroid Hormone Positive Regulation Of Protein Transport Cell Communication By Electrical Coupling
Tagcloud ?		absent antiserum b1 cardiomyocyte cast discs doubt dreifuss dystrophy edmd emerin emery explanation intercalated intranuclear lamin lamina lap1 lap2 libraries localize mabs muscular myocyte nuclei phage recognize rim spots
Tagcloud (Difference) ?		absent antiserum b1 cardiomyocyte cast discs doubt dreifuss dystrophy edmd emerin emery explanation intercalated intranuclear lamin lamina lap1 lap2 libraries localize mabs muscular myocyte nuclei phage recognize rim spots
Tagcloud (Intersection) ?