AKAP8L and SAMD4A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		AKAP8L	SAMD4A
Description		A-kinase anchoring protein 8 like	sterile alpha motif domain containing 4A
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Matrix PML Body Nuclear Speck Ribonucleoprotein Complex	P-body Fibrillar Center Cytoplasm Cytosol Cell Junction Dendrite Cell Projection Neuron Projection Synapse
	Molecular Function	DNA Binding RNA Binding Protein Binding Lamin Binding Zinc Ion Binding DEAD/H-box RNA Helicase Binding Protein Kinase A Regulatory Subunit Binding Histone Deacetylase Binding Metal Ion Binding	RNA Binding MRNA Binding Protein Binding Translation Repressor Activity
	Biological Process	MRNA Processing Mitotic Chromosome Condensation RNA Splicing Regulation Of MRNA Export From Nucleus Cell Cycle G2/M Phase Transition Positive Regulation Of Transcription By RNA Polymerase II Nuclear Membrane Disassembly	Nuclear-transcribed MRNA Poly(A) Tail Shortening Regulation Of Translation Negative Regulation Of Translation Regulation Of MRNA Stability Positive Regulation Of Translation
Pathways		Formation of WDR5-containing histone-modifying complexes
Drugs
Diseases
GWAS		Red blood cell count ( 32888494)	Aspartate aminotransferase levels ( 33547301) Cortical amyloid beta load ( 29860282) Creatine kinase levels ( 29403010) Hand grip strength ( 29313844) Height ( 31562340) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661) Plateletcrit ( 27863252) Pulse pressure ( 30224653) Subclinical trait of interstitial lung disease (basilar percentage of high attenuation areas on CT scan) ( 28521775) Tea consumption ( 31046077) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		60 interacting genes: ABI2 ATOSB ATPAF2 CARHSP1 CATSPER1 CCDC120 CCDC24 CDC6 CNNM3 CREB5 CSTF2 CSTF2T DGCR6 DHX9 DMRT3 DSCR9 EMD ENKD1 FOXD4 GPANK1 GPS2 HEMK1 HGS HSF4 HUNK INCA1 KPRP LAGE3 LBR MYOZ1 MYPOP PATZ1 PCDHB14 PEF1 PITX1 PLEKHN1 PRKAA2 PRKACA PRPF40A PTP4A2 RAMAC RTP5 RUSC1 SAMD4A SAXO1 SAXO4 SH3RF2 SNRPC TEKT4 TEKT5 TENT5B TFAP2D TIAL1 TLE5 TMPO TMSB4X TRIB3 TSGA10IP WDR25 ZNF366	14 interacting genes: AKAP8L ANKRA2 BAG4 GOLGA2 HSF2BP MEOX2 MTUS2 NFKBID NUTM1 PRDM6 PRKAB2 SNCA TBC1D21 YWHAG
Entrez ID		26993	23034
HPRD ID		10641	10209
Ensembl ID		ENSG00000011243	ENSG00000020577
Uniprot IDs		Q9ULX6	G3V2R1 Q8WW19 Q9UPU9
PDB IDs			8OIK
Enriched GO Terms of Interacting Partners?		Protein Binding Sperm Flagellum
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