AKAP8L and ZNF366

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		AKAP8L	ZNF366
Description		A-kinase anchoring protein 8 like	zinc finger protein 366
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Matrix PML Body Nuclear Speck Ribonucleoprotein Complex	Nucleus Nucleoplasm
	Molecular Function	DNA Binding RNA Binding Protein Binding Lamin Binding Zinc Ion Binding DEAD/H-box RNA Helicase Binding Protein Kinase A Regulatory Subunit Binding Histone Deacetylase Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding Nuclear Estrogen Receptor Binding Metal Ion Binding
	Biological Process	MRNA Processing Mitotic Chromosome Condensation RNA Splicing Regulation Of MRNA Export From Nucleus Cell Cycle G2/M Phase Transition Positive Regulation Of Transcription By RNA Polymerase II Nuclear Membrane Disassembly	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Estrogen
Pathways		Formation of WDR5-containing histone-modifying complexes
Drugs
Diseases
GWAS		Red blood cell count ( 32888494)	Apolipoprotein B levels ( 32203549) Asthma (childhood onset) ( 31036433) Bone mineral density (Ward's triangle area) ( 27397699) Heel bone mineral density ( 30598549) Hip geometry ( 17903296) Intraocular pressure ( 29617998) LDL cholesterol levels ( 32203549) Liver enzyme levels (alkaline phosphatase) ( 33972514) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 27863252 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Refractive error ( 32231278) Rheumatoid arthritis ( 30891314) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Stress sensitivity (neuroticism score x major depressive disorder status interaction) ( 30571770) Waist circumference adjusted for body mass index ( 34021172) White blood cell count ( 32888494)
Interacting Genes		60 interacting genes: ABI2 ATOSB ATPAF2 CARHSP1 CATSPER1 CCDC120 CCDC24 CDC6 CNNM3 CREB5 CSTF2 CSTF2T DGCR6 DHX9 DMRT3 DSCR9 EMD ENKD1 FOXD4 GPANK1 GPS2 HEMK1 HGS HSF4 HUNK INCA1 KPRP LAGE3 LBR MYOZ1 MYPOP PATZ1 PCDHB14 PEF1 PITX1 PLEKHN1 PRKAA2 PRKACA PRPF40A PTP4A2 RAMAC RTP5 RUSC1 SAMD4A SAXO1 SAXO4 SH3RF2 SNRPC TEKT4 TEKT5 TENT5B TFAP2D TIAL1 TLE5 TMPO TMSB4X TRIB3 TSGA10IP WDR25 ZNF366	5 interacting genes: AKAP8L CARD10 CEP70 PSMA3 TRIM54
Entrez ID		26993	167465
HPRD ID		10641	18329
Ensembl ID		ENSG00000011243	ENSG00000178175
Uniprot IDs		Q9ULX6	Q8N895
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Sperm Flagellum
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