AKAP8L and RAMAC

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		AKAP8L	RAMAC
Description		A-kinase anchoring protein 8 like	RNA guanine-7 methyltransferase activating subunit
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Matrix PML Body Nuclear Speck Ribonucleoprotein Complex	Nucleus MRNA Capping Enzyme Complex MRNA Cap Methyltransferase RNMT:RAMAC Complex
	Molecular Function	DNA Binding RNA Binding Protein Binding Lamin Binding Zinc Ion Binding DEAD/H-box RNA Helicase Binding Protein Kinase A Regulatory Subunit Binding Histone Deacetylase Binding Metal Ion Binding	RNA Binding Protein Binding Enzyme Activator Activity Molecular Function Activator Activity
	Biological Process	MRNA Processing Mitotic Chromosome Condensation RNA Splicing Regulation Of MRNA Export From Nucleus Cell Cycle G2/M Phase Transition Positive Regulation Of Transcription By RNA Polymerase II Nuclear Membrane Disassembly	7-methylguanosine MRNA Capping MRNA Processing RNA 5'-cap (guanine-N7)-methylation
Pathways		Formation of WDR5-containing histone-modifying complexes
Drugs
Diseases
GWAS		Red blood cell count ( 32888494)
Interacting Genes		60 interacting genes: ABI2 ATOSB ATPAF2 CARHSP1 CATSPER1 CCDC120 CCDC24 CDC6 CNNM3 CREB5 CSTF2 CSTF2T DGCR6 DHX9 DMRT3 DSCR9 EMD ENKD1 FOXD4 GPANK1 GPS2 HEMK1 HGS HSF4 HUNK INCA1 KPRP LAGE3 LBR MYOZ1 MYPOP PATZ1 PCDHB14 PEF1 PITX1 PLEKHN1 PRKAA2 PRKACA PRPF40A PTP4A2 RAMAC RTP5 RUSC1 SAMD4A SAXO1 SAXO4 SH3RF2 SNRPC TEKT4 TEKT5 TENT5B TFAP2D TIAL1 TLE5 TMPO TMSB4X TRIB3 TSGA10IP WDR25 ZNF366	47 interacting genes: AKAP8L BAG4 BPIFA1 C10orf55 CYSRT1 DAB1 DAZAP2 DMRTB1 FAM168B FOXI1 GOLGA2 HNRNPH1 HNRNPK INCA1 KRT15 KRT31 KRT33B KRTAP1-3 KRTAP8-1 LZTS2 MAGED1 MAPK1IP1L NAF1 OXER1 PEA15 PLSCR1 PLSCR4 POU2AF1 PRR3 PSMA3 RBMX RBMY1F RBPMS RHOXF2 RINT1 SF3B4 SNRPC TEKT3 TEKT4 TNS2 TRIM23 TRIM27 TRIM42 UBC USP54 VPS37C WWOX
Entrez ID		26993	83640
HPRD ID		10641	12845
Ensembl ID		ENSG00000011243	ENSG00000169612
Uniprot IDs		Q9ULX6	Q9BTL3
PDB IDs			5E8J
Enriched GO Terms of Interacting Partners?		Protein Binding Sperm Flagellum	Identical Protein Binding Protein Binding Spliceosomal Complex Structural Constituent Of Skin Epidermis RNA Splicing Intermediate Filament Regulation Of RNA Splicing Nucleic Acid Binding Keratin Filament Transcription Coactivator Activity MRNA Splicing, Via Spliceosome MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome CD4 Receptor Binding RNA Splicing, Via Transesterification Reactions RNA Processing Regulation Of MRNA Processing Ribonucleoprotein Complex RNA Binding Positive Regulation Of Apoptotic Signaling Pathway
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