LBR and FNBP4

Number of citations of the paper that reports this interaction (PMID 10744724)
19

Data Source:
HPRD (in vitro)

		LBR	FNBP4
Gene Name		lamin B receptor	formin binding protein 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Envelope Integral Component Of Nuclear Inner Membrane Membrane Integral Component Of Membrane Nuclear Membrane	Nucleoplasm
	Molecular Function	DNA Binding Protein Binding Lamin Binding Oxidoreductase Activity, Acting On The CH-CH Group Of Donors, NAD Or NADP As Acceptor Poly(A) RNA Binding Chromo Shadow Domain Binding	Protein Binding
	Biological Process	Cholesterol Biosynthetic Process Small Molecule Metabolic Process Oxidation-reduction Process
Pathways		Cholesterol biosynthesis Metabolism of lipids and lipoproteins
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: AKAP8L CBX3 CBX5 FNBP4 HIST1H3A HIST2H4A LMNB1 MECP2 PRM1 SRPK1 YWHAG	10 interactors: CSNK2A1 FYN ITSN1 ITSN2 KHDRBS1 LBR PLXNA2 PRPF40A SNRPB SYNJ1
Entrez ID		3930	23360
HPRD ID		02488	10996
Ensembl ID		ENSG00000143815	ENSG00000109920
Uniprot IDs		Q14739	B3KNP0 Q8N3X1
PDB IDs		2DIG
Enriched GO Terms of Interacting Partners?		Chromatin Silencing DNA Packaging Chromosome Organization Negative Regulation Of Gene Expression, Epigenetic DNA Conformation Change Chromatin Organization DNA Replication-dependent Nucleosome Assembly Gene Silencing DNA Methylation On Cytosine Chromatin Silencing At RDNA Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Organelle Organization Negative Regulation Of Cellular Metabolic Process Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process DNA Methylation Methylation DNA Modification DNA Metabolic Process Nucleosome Assembly Histone H4-K20 Demethylation Chromatin Assembly Nucleosome Organization Catecholamine Secretion Chromatin Modification Chromatin Assembly Or Disassembly Negative Regulation Of Megakaryocyte Differentiation Proprioception Protein-DNA Complex Assembly Regulation Of Synaptic Plasticity Chromatin Remodeling Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Sperm Chromatin Condensation Regulation Of RNA Metabolic Process Cardiolipin Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Respiratory Gaseous Exchange By Neurological System Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Neuromuscular Process Controlling Posture Regulation Of Synaptic Transmission Regulation Of Respiratory System Process Regulation Of Gene Expression Glucocorticoid Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process See more	Axon Guidance Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Locomotion Positive Regulation Of Signal Transduction Neuron Projection Morphogenesis Synaptic Vesicle Endocytosis Synaptic Vesicle Recycling Endocytosis Cell Morphogenesis Involved In Differentiation Movement Of Cell Or Subcellular Component Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Neuron Development Cerebellar Granule Cell Precursor Tangential Migration Positive Regulation Of Synaptic Vesicle Uncoating Synaptic Vesicle Uncoating Regulation Of Synaptic Vesicle Membrane Organization Organelle Localization Regulation Of Signaling MRNA Processing Cell Morphogenesis Ephrin Receptor Signaling Pathway Neuron Differentiation Hindbrain Tangential Cell Migration Positive Regulation Of RNA Export From Nucleus Cell Projection Organization Synaptic Vesicle Transport Negative Regulation Of Protein Catabolic Process MRNA Metabolic Process Positive Regulation Of Synaptic Vesicle Endocytosis RNA Processing Learning Regulation Of Cell Shape Vesicle-mediated Transport Negative Regulation Of Neuron Apoptotic Process Regulation Of Synaptic Vesicle Endocytosis Generation Of Neurons Negative Regulation Of Neuron Death Establishment Of Vesicle Localization Regulation Of Signal Transduction Regulation Of Synaptic Vesicle Recycling Synaptic Vesicle Priming Vesicle Localization Neurogenesis Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway See more
Tagcloud ?		absent antiserum b1 cardiomyocyte cast discs doubt dreifuss dystrophy edmd emerin emery explanation intercalated intranuclear lamin lamina lap1 lap2 libraries localize mabs muscular myocyte nuclei phage recognize rim spots	athanogene bag3 bcl2 cancerous developmentally e3 formin guanylatekinase ligase magi1 modulator nedd4 oncogene oncogenic oxidoreductase pdz property rab2a sgsm3 tumorigenic unchanged wbp2 wbp2nl ww wwox wwp1 wwtr1 yap1 yes
Tagcloud (Difference) ?		absent antiserum b1 cardiomyocyte cast discs doubt dreifuss dystrophy edmd emerin emery explanation intercalated intranuclear lamin lamina lap1 lap2 libraries localize mabs muscular myocyte nuclei phage recognize rim spots	athanogene bag3 bcl2 cancerous developmentally e3 formin guanylatekinase ligase magi1 modulator nedd4 oncogene oncogenic oxidoreductase pdz property rab2a sgsm3 tumorigenic unchanged wbp2 wbp2nl ww wwox wwp1 wwtr1 yap1 yes
Tagcloud (Intersection) ?