AKAP8L and CARHSP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		AKAP8L	CARHSP1
Description		A-kinase anchoring protein 8 like	calcium regulated heat stable protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Matrix PML Body Nuclear Speck Ribonucleoprotein Complex	Cytoplasmic Exosome (RNase Complex) P-body Cytoplasm Cytosol P Granule
	Molecular Function	DNA Binding RNA Binding Protein Binding Lamin Binding Zinc Ion Binding DEAD/H-box RNA Helicase Binding Protein Kinase A Regulatory Subunit Binding Histone Deacetylase Binding Metal Ion Binding	Nucleic Acid Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Phosphatase Binding
	Biological Process	MRNA Processing Mitotic Chromosome Condensation RNA Splicing Regulation Of MRNA Export From Nucleus Cell Cycle G2/M Phase Transition Positive Regulation Of Transcription By RNA Polymerase II Nuclear Membrane Disassembly	Intracellular Signal Transduction Regulation Of MRNA Stability
Pathways		Formation of WDR5-containing histone-modifying complexes
Drugs
Diseases
GWAS		Red blood cell count ( 32888494)	Alanine aminotransferase levels ( 33339817) Intracranial aneurysm ( 29531279)
Interacting Genes		60 interacting genes: ABI2 ATOSB ATPAF2 CARHSP1 CATSPER1 CCDC120 CCDC24 CDC6 CNNM3 CREB5 CSTF2 CSTF2T DGCR6 DHX9 DMRT3 DSCR9 EMD ENKD1 FOXD4 GPANK1 GPS2 HEMK1 HGS HSF4 HUNK INCA1 KPRP LAGE3 LBR MYOZ1 MYPOP PATZ1 PCDHB14 PEF1 PITX1 PLEKHN1 PRKAA2 PRKACA PRPF40A PTP4A2 RAMAC RTP5 RUSC1 SAMD4A SAXO1 SAXO4 SH3RF2 SNRPC TEKT4 TEKT5 TENT5B TFAP2D TIAL1 TLE5 TMPO TMSB4X TRIB3 TSGA10IP WDR25 ZNF366	26 interacting genes: AKAP8L AKT1 CDC42 CYSRT1 DOCK8 GORASP2 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP6-3 MID2 NBPF19 NOTCH2NLA PIAS3 PIN1 PNMA1 PPP2R1A RPS6KA1 SGK1 SMN1 SRPK2 STC2 STYX TK1 TRAF1 TSC22D1
Entrez ID		26993	23589
HPRD ID		10641	08515
Ensembl ID		ENSG00000011243	ENSG00000153048
Uniprot IDs		Q9ULX6	Q9Y2V2
PDB IDs			3AQQ
Enriched GO Terms of Interacting Partners?		Protein Binding Sperm Flagellum	Protein Serine/threonine/tyrosine Kinase Activity Regulation Of Signal Transduction Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Leading Edge Membrane Thioesterase Binding Intermediate Filament Intracellular Signal Transduction Regulation Of Cell Communication Glutamatergic Synapse Regulation Of Signaling Identical Protein Binding Regulation Of Growth Keratin Filament Nuclear Speck
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