KRT19 and IKZF3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KRT19	IKZF3
Gene Name		keratin 19, type I	IKAROS family zinc finger 3 (Aiolos)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intermediate Filament Dystrophin-associated Glycoprotein Complex Z Disc Sarcolemma Costamere Extracellular Vesicular Exosome Cell Periphery	Nucleus Cytoplasm Plasma Membrane
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Muscle Protein Complex Binding	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Homodimerization Activity Sequence-specific DNA Binding Metal Ion Binding Protein Heterodimerization Activity
	Biological Process	Viral Process Response To Estrogen Sarcomere Organization Cell Differentiation Involved In Embryonic Placenta Development	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Mesoderm Development Regulation Of B Cell Proliferation B Cell Activation Regulation Of Apoptotic Process Regulation Of B Cell Differentiation Regulation Of Lymphocyte Differentiation
Pathways
Drugs
Diseases
GWAS			Crohn's disease ( 21102463) Inflammatory bowel disease ( 23128233) Primary biliary cirrhosis ( 19458352 23000144 20639880) Rheumatoid arthritis ( 20453842) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Ulcerative colitis ( 21297633)
Protein-Protein Interactions		37 interactors: ABI2 AMOTL2 APC C10orf10 C1orf109 CARD9 CCDC146 CEP57L1 DGCR6L DMD EIF4E2 EIF4ENIF1 EXOC8 FAM107A FAM124B FANCG HAUS1 HGS IKZF3 KDM1A KIFC3 KRT15 KRT2 KRT6B PCM1 PLEKHA5 PNN POLR1C PPP1R18 SFI1 TBC1D7 TFPT TUBG1 UBE2I UCHL5 USHBP1 ZNF638	71 interactors: ABLIM3 AES AKAP9 AQP1 ARMC7 ARNT2 ATPAF2 BCAS2 BCL2L1 C1orf109 CABP5 CDKN1A CDKN2D CHCHD2 CHD3 DGCR6 EFHC1 EMC2 EXOC8 EXOSC5 FANCL FARS2 FBF1 GEM GRB2 HNRNPF HRAS IKZF1 IKZF4 IKZF5 ING5 KAT5 KRT19 LGALS14 LMO1 LMO2 MAGOHB MORN3 MRPL28 MRPL53 NATD1 NEK6 OAZ3 OSGIN1 PCID2 PFDN5 PIK3R2 PIN1 POLM POLR1C PPP1R16B PRKAA1 PRKAB2 PSMA1 RAD51D RBBP8 RCOR3 RHOA SPG21 STAMBPL1 STK16 STX11 TBC1D22B TCAF1 TEKT4 TRAPPC6A TRIM42 TSSK3 TSTD2 UBE2I ZGPAT
Entrez ID		3880	22806
HPRD ID		01007	05869
Ensembl ID		ENSG00000171345
Uniprot IDs		P08727	Q9UKT9
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoplasmic Microtubule Organization Organelle Organization Mitotic Cell Cycle Process Microtubule Cytoskeleton Organization Cell Cycle Process Mitotic Cell Cycle Microtubule-based Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition G2/M Transition Of Mitotic Cell Cycle Muscle Cell Cellular Homeostasis Cell Cycle Keratinocyte Activation Regulation Of Primitive Erythrocyte Differentiation Positive Regulation Of SUMO Transferase Activity Exocyst Assembly Microtubule Anchoring Nucleus Localization Negative Regulation Of Intracellular Signal Transduction Cytoskeleton Organization	Cell Cycle Cell Cycle Process Mitotic Cell Cycle Process Organelle Organization Gene Expression Mitotic Cell Cycle Negative Regulation Of Cellular Metabolic Process Cellular Response To Stress Cellular Response To DNA Damage Stimulus Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Response To Radiation Regulation Of Cell Cycle Positive Regulation Of Metabolic Process Cellular Response To Organonitrogen Compound Response To Hormone Nucleobase-containing Compound Metabolic Process Cell Cycle Checkpoint RNA Metabolic Process Response To Ionizing Radiation Cell Cycle Arrest Regulation Of Signal Transduction Insulin Receptor Signaling Pathway Response To Organic Substance Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Mitotic Cell Cycle Immune System Process Response To Stress Nitrogen Compound Metabolic Process Signal Transduction In Response To DNA Damage Negative Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Hormone Stimulus Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Negative Regulation Of Cell Cycle Cellular Macromolecule Biosynthetic Process Transcription, DNA-templated Regulation Of Signaling Ammonium Transmembrane Transport Biosynthetic Process Macromolecule Biosynthetic Process Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Cellular Response To Organic Substance Response To Organonitrogen Compound
Tagcloud ?		allograft biomarkers changed chronic clu cr diagnose differential difficult itraq latter lcn2 liver maldi olt option orthotopic predicting quantified re rejection reliable relt sixty tof transplantation treat understand unfortunately	17q12 amplicon cab2 ccct darpp32 endued gc han haplotype histogenesis immumohistochemical implied per1 perld1 ppp1r1b q21 rs11869286 rs1877031 rs881844 rs9972882 sequenom signet stard3 steroidogenic tcap titin tma top2a znfn1a3
Tagcloud (Difference) ?		allograft biomarkers changed chronic clu cr diagnose differential difficult itraq latter lcn2 liver maldi olt option orthotopic predicting quantified re rejection reliable relt sixty tof transplantation treat understand unfortunately	17q12 amplicon cab2 ccct darpp32 endued gc han haplotype histogenesis immumohistochemical implied per1 perld1 ppp1r1b q21 rs11869286 rs1877031 rs881844 rs9972882 sequenom signet stard3 steroidogenic tcap titin tma top2a znfn1a3
Tagcloud (Intersection) ?