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IKZF3 and LGALS14
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
IKZF3
LGALS14
Gene Name
IKAROS family zinc finger 3 (Aiolos)
lectin, galactoside-binding, soluble, 14
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Plasma Membrane
Nucleus
Molecular Function
Sequence-specific DNA Binding Transcription Factor Activity
Protein Binding
Protein Homodimerization Activity
Sequence-specific DNA Binding
Metal Ion Binding
Protein Heterodimerization Activity
Carbohydrate Binding
Biological Process
Transcription, DNA-templated
Regulation Of Transcription From RNA Polymerase II Promoter
Mesoderm Development
Regulation Of B Cell Proliferation
B Cell Activation
Regulation Of Apoptotic Process
Regulation Of B Cell Differentiation
Regulation Of Lymphocyte Differentiation
Apoptotic Process
Pathways
Drugs
Diseases
GWAS
Crohn's disease (
21102463
)
Inflammatory bowel disease (
23128233
)
Primary biliary cirrhosis (
19458352
23000144
20639880
)
Rheumatoid arthritis (
20453842
)
Systemic lupus erythematosus and Systemic sclerosis (
23740937
)
Ulcerative colitis (
21297633
)
Protein-Protein Interactions
71 interactors:
ABLIM3
AES
AKAP9
AQP1
ARMC7
ARNT2
ATPAF2
BCAS2
BCL2L1
C1orf109
CABP5
CDKN1A
CDKN2D
CHCHD2
CHD3
DGCR6
EFHC1
EMC2
EXOC8
EXOSC5
FANCL
FARS2
FBF1
GEM
GRB2
HNRNPF
HRAS
IKZF1
IKZF4
IKZF5
ING5
KAT5
KRT19
LGALS14
LMO1
LMO2
MAGOHB
MORN3
MRPL28
MRPL53
NATD1
NEK6
OAZ3
OSGIN1
PCID2
PFDN5
PIK3R2
PIN1
POLM
POLR1C
PPP1R16B
PRKAA1
PRKAB2
PSMA1
RAD51D
RBBP8
RCOR3
RHOA
SPG21
STAMBPL1
STK16
STX11
TBC1D22B
TCAF1
TEKT4
TRAPPC6A
TRIM42
TSSK3
TSTD2
UBE2I
ZGPAT
15 interactors:
ADAMTSL4
BANP
CRLF3
FCHO1
FLNA
GFAP
IKZF3
LNX1
MID2
REL
SDCBP2
SPAG5
TCF4
TNR
TRIM27
Entrez ID
22806
56891
HPRD ID
05869
06268
Ensembl ID
ENSG00000006659
Uniprot IDs
Q9UKT9
Q8TCE9
PDB IDs
Enriched GO Terms of Interacting Partners
?
Cell Cycle
Cell Cycle Process
Mitotic Cell Cycle Process
Organelle Organization
Gene Expression
Mitotic Cell Cycle
Negative Regulation Of Cellular Metabolic Process
Cellular Response To Stress
Cellular Response To DNA Damage Stimulus
Regulation Of Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Response To Radiation
Regulation Of Cell Cycle
Positive Regulation Of Metabolic Process
Cellular Response To Organonitrogen Compound
Response To Hormone
Nucleobase-containing Compound Metabolic Process
Cell Cycle Checkpoint
RNA Metabolic Process
Response To Ionizing Radiation
Cell Cycle Arrest
Regulation Of Signal Transduction
Insulin Receptor Signaling Pathway
Response To Organic Substance
Regulation Of Transcription From RNA Polymerase II Promoter
Heterocycle Metabolic Process
Cellular Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Mitotic Cell Cycle
Immune System Process
Response To Stress
Nitrogen Compound Metabolic Process
Signal Transduction In Response To DNA Damage
Negative Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Cellular Response To Hormone Stimulus
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Gene Expression
Negative Regulation Of Cell Cycle
Cellular Macromolecule Biosynthetic Process
Transcription, DNA-templated
Regulation Of Signaling
Ammonium Transmembrane Transport
Biosynthetic Process
Macromolecule Biosynthetic Process
Neurotrophin TRK Receptor Signaling Pathway
Cellular Response To Insulin Stimulus
Cellular Response To Organic Substance
Response To Organonitrogen Compound
Negative Regulation Of Viral Release From Host Cell
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Negative Regulation Of Viral Transcription
Regulation Of Viral Release From Host Cell
Positive Regulation Of Intracellular Signal Transduction
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Growth
Long-term Synaptic Potentiation
Positive Regulation Of Schwann Cell Proliferation
Negative Regulation Of Axon Extension Involved In Regeneration
Regulation Of Cellular Component Organization
Positive Regulation Of Signal Transduction
Regulation Of Viral Transcription
Negative Regulation Of Viral Process
Cell Cycle
Regulation Of Protein Localization
Negative Regulation Of Interleukin-2 Secretion
Catenin Import Into Nucleus
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Negative Regulation Of Developmental Growth
Extracellular Matrix Organization
Extracellular Structure Organization
Regulation Of Signaling
Organelle Organization
Transcription, DNA-templated
Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
Glial Cell Development
Regulation Of Gliogenesis
Regulation Of Transcription, DNA-templated
Positive Regulation Of Nucleocytoplasmic Transport
RNA Biosynthetic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Positive Regulation Of Synaptic Transmission
Cellular Localization
Negative Regulation Of Protein Catabolic Process
Maintenance Of DNA Repeat Elements
Negative Regulation Of Neuron Projection Development
Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of RNA Metabolic Process
Spindle Organization
Protein Complex Assembly
Regulation Of Cellular Localization
Cell Cycle Process
Regulation Of Intracellular Signal Transduction
Cytokine Production
Negative Regulation Of Cell Projection Organization
Cellular Macromolecule Biosynthetic Process
Protein Localization To Organelle
Tagcloud
?
17q12
amplicon
cab2
ccct
darpp32
endued
gc
han
haplotype
histogenesis
immumohistochemical
implied
per1
perld1
ppp1r1b
q21
rs11869286
rs1877031
rs881844
rs9972882
sequenom
signet
stard3
steroidogenic
tcap
titin
tma
top2a
znfn1a3
Tagcloud (Difference)
?
17q12
amplicon
cab2
ccct
darpp32
endued
gc
han
haplotype
histogenesis
immumohistochemical
implied
per1
perld1
ppp1r1b
q21
rs11869286
rs1877031
rs881844
rs9972882
sequenom
signet
stard3
steroidogenic
tcap
titin
tma
top2a
znfn1a3
Tagcloud (Intersection)
?