IKZF3 and STX11

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		IKZF3	STX11
Gene Name		IKAROS family zinc finger 3 (Aiolos)	syntaxin 11
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane	Golgi Apparatus Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane SNARE Complex
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Homodimerization Activity Sequence-specific DNA Binding Metal Ion Binding Protein Heterodimerization Activity	SNARE Binding SNAP Receptor Activity Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Mesoderm Development Regulation Of B Cell Proliferation B Cell Activation Regulation Of Apoptotic Process Regulation Of B Cell Differentiation Regulation Of Lymphocyte Differentiation	Intracellular Protein Transport Synaptic Vesicle Fusion To Presynaptic Membrane Neutrophil Degranulation Cytotoxic T Cell Degranulation Natural Killer Cell Degranulation Vesicle Docking Membrane Fusion
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 21102463) Inflammatory bowel disease ( 23128233) Primary biliary cirrhosis ( 19458352 23000144 20639880) Rheumatoid arthritis ( 20453842) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Ulcerative colitis ( 21297633)
Protein-Protein Interactions		71 interactors: ABLIM3 AES AKAP9 AQP1 ARMC7 ARNT2 ATPAF2 BCAS2 BCL2L1 C1orf109 CABP5 CDKN1A CDKN2D CHCHD2 CHD3 DGCR6 EFHC1 EMC2 EXOC8 EXOSC5 FANCL FARS2 FBF1 GEM GRB2 HNRNPF HRAS IKZF1 IKZF4 IKZF5 ING5 KAT5 KRT19 LGALS14 LMO1 LMO2 MAGOHB MORN3 MRPL28 MRPL53 NATD1 NEK6 OAZ3 OSGIN1 PCID2 PFDN5 PIK3R2 PIN1 POLM POLR1C PPP1R16B PRKAA1 PRKAB2 PSMA1 RAD51D RBBP8 RCOR3 RHOA SPG21 STAMBPL1 STK16 STX11 TBC1D22B TCAF1 TEKT4 TRAPPC6A TRIM42 TSSK3 TSTD2 UBE2I ZGPAT	62 interactors: AES APP BLOC1S6 BYSL C1orf109 CARD9 CCBE1 CCDC184 CCDC33 CCNK CDCA7L CTBP2 CWF19L2 EIF1AD FAM110A FAM161A FAM74A4 FAM90A1 FARS2 FHL5 GOLGA8EP GOLGA8F HAUS1 IKBKG IKZF3 KAT5 KCTD9 KDM1A KLC3 KXD1 LENG1 LONRF1 MBIP MEOX2 MFAP1 MID2 NDC80 PPP1R18 PRKAB2 PRPF31 PSMA3 PSMC3 RUNX1T1 SH2D4A SLC38A2 SMARCE1 SNAP23 SNAP25 SNX3 STXBP1 SUV39H1 TAF6L TBK1 TCF4 TNFRSF21 USHBP1 VAMP2 VPS52 WDYHV1 ZCCHC10 ZNF417 ZNF587
Entrez ID		22806	8676
HPRD ID		05869	09231
Ensembl ID
Uniprot IDs		Q9UKT9	O75558
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Cell Cycle Process Mitotic Cell Cycle Process Organelle Organization Gene Expression Mitotic Cell Cycle Negative Regulation Of Cellular Metabolic Process Cellular Response To Stress Cellular Response To DNA Damage Stimulus Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Response To Radiation Regulation Of Cell Cycle Positive Regulation Of Metabolic Process Cellular Response To Organonitrogen Compound Response To Hormone Nucleobase-containing Compound Metabolic Process Cell Cycle Checkpoint RNA Metabolic Process Response To Ionizing Radiation Cell Cycle Arrest Regulation Of Signal Transduction Insulin Receptor Signaling Pathway Response To Organic Substance Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Mitotic Cell Cycle Immune System Process Response To Stress Nitrogen Compound Metabolic Process Signal Transduction In Response To DNA Damage Negative Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Hormone Stimulus Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Negative Regulation Of Cell Cycle Cellular Macromolecule Biosynthetic Process Transcription, DNA-templated Regulation Of Signaling Ammonium Transmembrane Transport Biosynthetic Process Macromolecule Biosynthetic Process Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Cellular Response To Organic Substance Response To Organonitrogen Compound	Neurotransmitter Secretion Glutamate Secretion Vesicle Localization Regulation Of Neurotransmitter Levels Neurotransmitter Transport Gene Expression Organelle Localization Synaptic Vesicle Transport Establishment Of Vesicle Localization Establishment Of Organelle Localization Vesicle Organization Synaptic Vesicle Exocytosis Acid Secretion Energy Reserve Metabolic Process RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Binding Dicarboxylic Acid Transport Organelle Organization Membrane Docking Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Exocytosis RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Secretion By Cell Regulation Of RNA Biosynthetic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Negative Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Signaling Regulation Of RNA Metabolic Process Viral Process Synaptic Vesicle Docking Membrane Fusion Axon Cargo Transport Synaptic Vesicle Priming Regulation Of Nitrogen Compound Metabolic Process Establishment Of Localization In Cell Vesicle Fusion Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Generation Of Precursor Metabolites And Energy Synaptic Vesicle Fusion To Presynaptic Membrane Regulation Of Protein Binding Negative Regulation Of Canonical Wnt Signaling Pathway Macromolecule Biosynthetic Process Cellular Localization
Tagcloud ?		17q12 amplicon cab2 ccct darpp32 endued gc han haplotype histogenesis immumohistochemical implied per1 perld1 ppp1r1b q21 rs11869286 rs1877031 rs881844 rs9972882 sequenom signet stard3 steroidogenic tcap titin tma top2a znfn1a3	autosomal characterised defect done dysregulation familial families fhl haemophagocytic harbour harbouring killer leukaemia lymphohistiocytosis milder mutational myelogenous nonsense perforin periods prf1 psychomotor recessive retardation segregation syntaxin uncommon undertaken unrelated
Tagcloud (Difference) ?		17q12 amplicon cab2 ccct darpp32 endued gc han haplotype histogenesis immumohistochemical implied per1 perld1 ppp1r1b q21 rs11869286 rs1877031 rs881844 rs9972882 sequenom signet stard3 steroidogenic tcap titin tma top2a znfn1a3	autosomal characterised defect done dysregulation familial families fhl haemophagocytic harbour harbouring killer leukaemia lymphohistiocytosis milder mutational myelogenous nonsense perforin periods prf1 psychomotor recessive retardation segregation syntaxin uncommon undertaken unrelated
Tagcloud (Intersection) ?