IKZF3 and C1orf109

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		IKZF3	C1orf109
Gene Name		IKAROS family zinc finger 3 (Aiolos)	chromosome 1 open reading frame 109
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Homodimerization Activity Sequence-specific DNA Binding Metal Ion Binding Protein Heterodimerization Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Mesoderm Development Regulation Of B Cell Proliferation B Cell Activation Regulation Of Apoptotic Process Regulation Of B Cell Differentiation Regulation Of Lymphocyte Differentiation
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 21102463) Inflammatory bowel disease ( 23128233) Primary biliary cirrhosis ( 19458352 23000144 20639880) Rheumatoid arthritis ( 20453842) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Ulcerative colitis ( 21297633)
Protein-Protein Interactions		71 interactors: ABLIM3 AES AKAP9 AQP1 ARMC7 ARNT2 ATPAF2 BCAS2 BCL2L1 C1orf109 CABP5 CDKN1A CDKN2D CHCHD2 CHD3 DGCR6 EFHC1 EMC2 EXOC8 EXOSC5 FANCL FARS2 FBF1 GEM GRB2 HNRNPF HRAS IKZF1 IKZF4 IKZF5 ING5 KAT5 KRT19 LGALS14 LMO1 LMO2 MAGOHB MORN3 MRPL28 MRPL53 NATD1 NEK6 OAZ3 OSGIN1 PCID2 PFDN5 PIK3R2 PIN1 POLM POLR1C PPP1R16B PRKAA1 PRKAB2 PSMA1 RAD51D RBBP8 RCOR3 RHOA SPG21 STAMBPL1 STK16 STX11 TBC1D22B TCAF1 TEKT4 TRAPPC6A TRIM42 TSSK3 TSTD2 UBE2I ZGPAT	44 interactors: AES C1orf94 CCDC36 CEP55 CINP CRX CSNK2A1 GOLGA2 IKZF1 IKZF3 KATNAL1 KIFC3 KRT13 KRT19 KRT31 KRT40 LDOC1 LZTS2 MEOX2 MKRN2 MTUS2 NECAB2 PDE4DIP PHC2 PLK4 PPP1R12C REL RINT1 RNF41 SDCBP SPAG5 SPERT STX11 TADA2A TCF12 TCF4 TFIP11 TRAF1 TRIM42 TRIM54 USHBP1 VPS52 ZBED1 ZNF398
Entrez ID		22806	54955
HPRD ID		05869	07918
Ensembl ID			ENSG00000116922
Uniprot IDs		Q9UKT9	B4DRQ5 Q9NX04
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Cell Cycle Process Mitotic Cell Cycle Process Organelle Organization Gene Expression Mitotic Cell Cycle Negative Regulation Of Cellular Metabolic Process Cellular Response To Stress Cellular Response To DNA Damage Stimulus Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Response To Radiation Regulation Of Cell Cycle Positive Regulation Of Metabolic Process Cellular Response To Organonitrogen Compound Response To Hormone Nucleobase-containing Compound Metabolic Process Cell Cycle Checkpoint RNA Metabolic Process Response To Ionizing Radiation Cell Cycle Arrest Regulation Of Signal Transduction Insulin Receptor Signaling Pathway Response To Organic Substance Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Mitotic Cell Cycle Immune System Process Response To Stress Nitrogen Compound Metabolic Process Signal Transduction In Response To DNA Damage Negative Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Hormone Stimulus Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Negative Regulation Of Cell Cycle Cellular Macromolecule Biosynthetic Process Transcription, DNA-templated Regulation Of Signaling Ammonium Transmembrane Transport Biosynthetic Process Macromolecule Biosynthetic Process Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Cellular Response To Organic Substance Response To Organonitrogen Compound	Cell Cycle Mitotic Cell Cycle Microtubule Severing Developmental Process Transcription, DNA-templated RNA Biosynthetic Process Mitotic Cell Cycle Process Multicellular Organismal Development Anatomical Structure Development Cell Cycle Process Positive Regulation Of Organelle Assembly Wnt Signaling Pathway Organ Development Microtubule-based Process Regulation Of Wnt Signaling Pathway Cytoskeleton Organization Organelle Organization Regulation Of Microtubule Cytoskeleton Organization System Development Cell Differentiation Involved In Embryonic Placenta Development RNA Metabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Protein Binding Transcription From RNA Polymerase II Promoter Regulation Of Lymphocyte Differentiation Regulation Of Transcription, DNA-templated Positive Regulation Of Neutrophil Differentiation Spliceosomal Complex Disassembly Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint Positive Regulation Of Photoreceptor Cell Differentiation Regulation Of Organelle Organization Regulation Of Nucleic Acid-templated Transcription Regulation Of Microtubule-based Process Regulation Of RNA Biosynthetic Process Embryonic Digestive Tract Development Regulation Of RNA Metabolic Process Gene Expression Positive Regulation Of Transcription, DNA-templated Tissue Development Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Division Negative Regulation Of Protein Binding Catenin Import Into Nucleus Positive Regulation Of Centriole Replication Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Embryonic Ectodermal Digestive Tract Development Cellular Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Microtubule Cytoskeleton Organization
Tagcloud ?		17q12 amplicon cab2 ccct darpp32 endued gc han haplotype histogenesis immumohistochemical implied per1 perld1 ppp1r1b q21 rs11869286 rs1877031 rs881844 rs9972882 sequenom signet stard3 steroidogenic tcap titin tma top2a znfn1a3
Tagcloud (Difference) ?		17q12 amplicon cab2 ccct darpp32 endued gc han haplotype histogenesis immumohistochemical implied per1 perld1 ppp1r1b q21 rs11869286 rs1877031 rs881844 rs9972882 sequenom signet stard3 steroidogenic tcap titin tma top2a znfn1a3
Tagcloud (Intersection) ?