KRT19 and POLR1C

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KRT19	POLR1C
Gene Name		keratin 19, type I	polymerase (RNA) I polypeptide C, 30kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intermediate Filament Dystrophin-associated Glycoprotein Complex Z Disc Sarcolemma Costamere Extracellular Vesicular Exosome Cell Periphery	Nucleoplasm DNA-directed RNA Polymerase III Complex DNA-directed RNA Polymerase I Complex Cytosol
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Muscle Protein Complex Binding	RNA Polymerase I Activity RNA Polymerase III Activity DNA Binding DNA-directed RNA Polymerase Activity Protein Dimerization Activity
	Biological Process	Viral Process Response To Estrogen Sarcomere Organization Cell Differentiation Involved In Embryonic Placenta Development	Transcription From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Transcription From RNA Polymerase III Promoter Transcription Elongation From RNA Polymerase III Promoter Termination Of RNA Polymerase III Transcription Gene Expression Positive Regulation Of Type I Interferon Production Regulation Of Gene Expression, Epigenetic Innate Immune Response Negative Regulation Of Gene Expression, Epigenetic
Pathways			RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Termination RNA Polymerase I Promoter Escape RNA Polymerase I Promoter Clearance Cytosolic sensors of pathogen-associated DNA Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Termination NoRC negatively regulates rRNA expression RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Chain Elongation Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		37 interactors: ABI2 AMOTL2 APC C10orf10 C1orf109 CARD9 CCDC146 CEP57L1 DGCR6L DMD EIF4E2 EIF4ENIF1 EXOC8 FAM107A FAM124B FANCG HAUS1 HGS IKZF3 KDM1A KIFC3 KRT15 KRT2 KRT6B PCM1 PLEKHA5 PNN POLR1C PPP1R18 SFI1 TBC1D7 TFPT TUBG1 UBE2I UCHL5 USHBP1 ZNF638	32 interactors: ATRIP BIRC7 CCDC33 CCDC36 CD3EAP CLU CORO1A CORO1B FAM154A FAM208B IKZF3 KCTD1 KRT19 LZTS2 MBIP MYD88 MYO5B NFKBIB NME1 POLR1D POLR1E POLR2J PPP2R3C RIMBP3 SMN2 TCF4 TNFAIP1 TRIM27 TRIOBP TSC22D4 VIM WRN
Entrez ID		3880	9533
HPRD ID		01007	09661
Ensembl ID		ENSG00000171345	ENSG00000171453
Uniprot IDs		P08727	O15160
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoplasmic Microtubule Organization Organelle Organization Mitotic Cell Cycle Process Microtubule Cytoskeleton Organization Cell Cycle Process Mitotic Cell Cycle Microtubule-based Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition G2/M Transition Of Mitotic Cell Cycle Muscle Cell Cellular Homeostasis Cell Cycle Keratinocyte Activation Regulation Of Primitive Erythrocyte Differentiation Positive Regulation Of SUMO Transferase Activity Exocyst Assembly Microtubule Anchoring Nucleus Localization Negative Regulation Of Intracellular Signal Transduction Cytoskeleton Organization	Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Type I Interferon Production Cytoskeleton Organization DNA-templated Transcription, Elongation Cellular Component Assembly Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter DNA-templated Transcription, Initiation Transcription Initiation From RNA Polymerase I Promoter Response To Stress Actin Filament-based Process Transcription From RNA Polymerase I Promoter Regulation Of Type I Interferon Production Organelle Organization Innate Immune Response Regulation Of Cytokine Production Nucleobase-containing Compound Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Heterocycle Metabolic Process Actin Cytoskeleton Organization Cellular Aromatic Compound Metabolic Process Positive Regulation Of Cytokine Production Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Immune Response Immune System Process DNA-templated Transcription, Termination Cellular Nitrogen Compound Metabolic Process Regulation Of Gene Expression, Epigenetic Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Transcription, DNA-templated Negative Regulation Of Actin Nucleation Response To Stimulus Regulation Of Apoptotic Process RNA Biosynthetic Process Termination Of RNA Polymerase III Transcription Transcription Elongation From RNA Polymerase III Promoter Regulation Of Metabolic Process Regulation Of Tumor Necrosis Factor Production Regulation Of Cell Death Glial Cell Development Biosynthetic Process Nitrogen Compound Metabolic Process RRNA Transcription Cellular Process Actin Filament Organization Regulation Of Actin Nucleation RNA Metabolic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Immune System Process
Tagcloud ?		allograft biomarkers changed chronic clu cr diagnose differential difficult itraq latter lcn2 liver maldi olt option orthotopic predicting quantified re rejection reliable relt sixty tof transplantation treat understand unfortunately	add biosynthesis burgeoning codified codifies collins constituent crest disrupts elucidating genetics hemizygous heterozygosity illustrating implicates nascent neuroepithelium pathophysiology planning playing researchers ribosome tcof1 tcs treacher treacle underpinnings utilizing
Tagcloud (Difference) ?		allograft biomarkers changed chronic clu cr diagnose differential difficult itraq latter lcn2 liver maldi olt option orthotopic predicting quantified re rejection reliable relt sixty tof transplantation treat understand unfortunately	add biosynthesis burgeoning codified codifies collins constituent crest disrupts elucidating genetics hemizygous heterozygosity illustrating implicates nascent neuroepithelium pathophysiology planning playing researchers ribosome tcof1 tcs treacher treacle underpinnings utilizing
Tagcloud (Intersection) ?