KRT19 and KRT76

Number of citations of the paper that reports this interaction (PubMedID 36949045)
82

Data Source:
BioGRID (two hybrid, cross-linking study)

		KRT19	KRT76
Description		keratin 19	keratin 76
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Intermediate Filament Plasma Membrane Dystrophin-associated Glycoprotein Complex Apicolateral Plasma Membrane Z Disc Sarcolemma Costamere Keratin Filament Extracellular Exosome Cell Periphery Terminal Web	Nucleus Cytosol Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Muscle Structural Constituent Of Skin Epidermis Protein-containing Complex Binding	Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Morphogenesis Of An Epithelium Notch Signaling Pathway Epithelial Cell Differentiation Response To Estrogen Intermediate Filament Organization Sarcomere Organization Cell Differentiation Involved In Embryonic Placenta Development	Cytoskeleton Organization Epidermis Development Keratinization Pigmentation Intermediate Filament Organization Sebaceous Gland Development
Pathways		Keratinization Formation of the cornified envelope Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin Developmental Lineage of Pancreatic Ductal Cells Developmental Lineage of Mammary Gland Luminal Epithelial Cells Developmental Lineage of Mammary Gland Alveolar Cells	Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS
Interacting Genes		75 interacting genes: ABI2 AIRIM AMOT AMOTL2 ARL4A BEX2 CARD9 CCDC146 CCHCR1 CEP57L1 COPS4 DEPP1 DGCR6L DMD EIF4E2 EIF4ENIF1 ESR1 EXOC8 FAM107A FAM124B FANCG GFAP GLYCTK HAUS1 HGS IKZF3 KDM1A KIFC3 KRT1 KRT15 KRT4 KRT6A KRT6B KRT6C KRT71 KRT72 KRT73 KRT74 KRT76 KRT77 KRT78 KRT79 KRT80 KRT81 KRT82 KRT83 KRT85 KRT86 LENG1 LGALS14 NFKBID PCDHB12 PCM1 PKN1 PLEKHA5 PNN POLL POLR1C PPP1R18 PSMA1 RCOR3 SFI1 SGF29 SMARCB1 SMARCE1 SNAPIN SPG21 TBC1D7 TCHP TFPT TUBG1 UBE2I UCHL5 USHBP1 ZNF638	47 interacting genes: AIRIM C1orf216 CAMK2A CCDC57 CDC37 CFAP206 DPPA3 EXOC8 FOXR2 FRS3 HGS IPO11 IQUB KIFC3 KRT13 KRT15 KRT16 KRT19 KRT25 KRT26 KRT27 KRT28 KRT31 KRT32 KRT33B KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 KRT75 KRT86 LCA5L LMO4 MID2 MTUS2 NFKBID POLR1C RSPH14 TNS2 TRIM23 TRIM27 TRIM54 TSGA10 WASHC1 ZNF655
Entrez ID		3880	51350
HPRD ID		01007	17123
Ensembl ID		ENSG00000171345	ENSG00000185069
Uniprot IDs		P08727	Q01546
PDB IDs		8XTN 8XTO 8Y3S 8ZUG
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Structural Constituent Of Skin Epidermis Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Keratin Filament Keratinization Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Cytosol Protein Binding Structural Constituent Of Cytoskeleton Establishment Of Cell Polarity Involved In Ameboidal Cell Migration Cytoskeleton Desmosome Epidermis Development Regulation Of Embryonic Development Regulation Of DNA Repair Cytoplasm	Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Supramolecular Fiber Organization Morphogenesis Of An Epithelium Cytoskeleton Epithelial Cell Differentiation Tissue Morphogenesis Cytoskeleton Organization Organelle Organization Extracellular Exosome Anatomical Structure Morphogenesis Cell Differentiation Radial Spoke Hair Cycle Protein Binding Cellular Developmental Process Cytosol Hair Follicle Morphogenesis Phosphatidylinositol 3-kinase Inhibitor Activity Structural Constituent Of Cytoskeleton Regulation Of Autophagy Developmental Process Epidermis Development Negative Regulation Of Viral Transcription Exocyst Keratinization Suppression Of Viral Release By Host Arp2/3 Complex-mediated Actin Nucleation Hair Cycle Process Positive Regulation Of Autophagy Regulation Of Viral Transcription Actin Nucleation
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