IKZF3 and OSGIN1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		IKZF3	OSGIN1
Gene Name		IKAROS family zinc finger 3 (Aiolos)	oxidative stress induced growth inhibitor 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane	Cellular_component
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Homodimerization Activity Sequence-specific DNA Binding Metal Ion Binding Protein Heterodimerization Activity	Growth Factor Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Mesoderm Development Regulation Of B Cell Proliferation B Cell Activation Regulation Of Apoptotic Process Regulation Of B Cell Differentiation Regulation Of Lymphocyte Differentiation	Multicellular Organismal Development Cell Differentiation Negative Regulation Of Cell Growth Positive Regulation Of Apoptotic Process
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 21102463) Inflammatory bowel disease ( 23128233) Primary biliary cirrhosis ( 19458352 23000144 20639880) Rheumatoid arthritis ( 20453842) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Ulcerative colitis ( 21297633)
Protein-Protein Interactions		71 interactors: ABLIM3 AES AKAP9 AQP1 ARMC7 ARNT2 ATPAF2 BCAS2 BCL2L1 C1orf109 CABP5 CDKN1A CDKN2D CHCHD2 CHD3 DGCR6 EFHC1 EMC2 EXOC8 EXOSC5 FANCL FARS2 FBF1 GEM GRB2 HNRNPF HRAS IKZF1 IKZF4 IKZF5 ING5 KAT5 KRT19 LGALS14 LMO1 LMO2 MAGOHB MORN3 MRPL28 MRPL53 NATD1 NEK6 OAZ3 OSGIN1 PCID2 PFDN5 PIK3R2 PIN1 POLM POLR1C PPP1R16B PRKAA1 PRKAB2 PSMA1 RAD51D RBBP8 RCOR3 RHOA SPG21 STAMBPL1 STK16 STX11 TBC1D22B TCAF1 TEKT4 TRAPPC6A TRIM42 TSSK3 TSTD2 UBE2I ZGPAT	14 interactors: AES CAPN3 CCDC33 CRX DNAJA3 FAM154A IKZF3 INCA1 LNX1 MEIS2 MEOX2 REL TCF12 TCF4
Entrez ID		22806	29948
HPRD ID		05869	06412
Ensembl ID			ENSG00000140961
Uniprot IDs		Q9UKT9	Q9UJX0
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Cell Cycle Process Mitotic Cell Cycle Process Organelle Organization Gene Expression Mitotic Cell Cycle Negative Regulation Of Cellular Metabolic Process Cellular Response To Stress Cellular Response To DNA Damage Stimulus Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Response To Radiation Regulation Of Cell Cycle Positive Regulation Of Metabolic Process Cellular Response To Organonitrogen Compound Response To Hormone Nucleobase-containing Compound Metabolic Process Cell Cycle Checkpoint RNA Metabolic Process Response To Ionizing Radiation Cell Cycle Arrest Regulation Of Signal Transduction Insulin Receptor Signaling Pathway Response To Organic Substance Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Mitotic Cell Cycle Immune System Process Response To Stress Nitrogen Compound Metabolic Process Signal Transduction In Response To DNA Damage Negative Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Hormone Stimulus Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Negative Regulation Of Cell Cycle Cellular Macromolecule Biosynthetic Process Transcription, DNA-templated Regulation Of Signaling Ammonium Transmembrane Transport Biosynthetic Process Macromolecule Biosynthetic Process Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Cellular Response To Organic Substance Response To Organonitrogen Compound	Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Positive Regulation Of Gene Expression Regulation Of Cell Death Positive Regulation Of Cellular Biosynthetic Process RNA Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Organ Development Negative Regulation Of Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process RNA Metabolic Process Regulation Of Apoptotic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Cell Differentiation Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Anatomical Structure Development Muscle Structure Development Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Cell Death Developmental Process Negative Regulation Of Response To Cytokine Stimulus Nitrogen Compound Metabolic Process System Development Muscle Organ Development Positive Regulation Of Neuron Differentiation
Tagcloud ?		17q12 amplicon cab2 ccct darpp32 endued gc han haplotype histogenesis immumohistochemical implied per1 perld1 ppp1r1b q21 rs11869286 rs1877031 rs881844 rs9972882 sequenom signet stard3 steroidogenic tcap titin tma top2a znfn1a3
Tagcloud (Difference) ?		17q12 amplicon cab2 ccct darpp32 endued gc han haplotype histogenesis immumohistochemical implied per1 perld1 ppp1r1b q21 rs11869286 rs1877031 rs881844 rs9972882 sequenom signet stard3 steroidogenic tcap titin tma top2a znfn1a3
Tagcloud (Intersection) ?