IKZF3 and OAZ3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		IKZF3	OAZ3
Gene Name		IKAROS family zinc finger 3 (Aiolos)	ornithine decarboxylase antizyme 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane	Nucleus Cytosol Sperm Flagellum Blood Microparticle
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Homodimerization Activity Sequence-specific DNA Binding Metal Ion Binding Protein Heterodimerization Activity	Protein Binding Ornithine Decarboxylase Inhibitor Activity Putrescine Transmembrane Transporter Activity Ankyrin Repeat Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Mesoderm Development Regulation Of B Cell Proliferation B Cell Activation Regulation Of Apoptotic Process Regulation Of B Cell Differentiation Regulation Of Lymphocyte Differentiation	Regulation Of Cellular Amino Acid Metabolic Process Polyamine Biosynthetic Process Spermatogenesis Putrescine Transport Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Catalytic Activity Regulation Of Phosphoprotein Phosphatase Activity Small Molecule Metabolic Process Positive Regulation Of Protein Catabolic Process Negative Regulation Of Polyamine Transmembrane Transport
Pathways			Regulation of ornithine decarboxylase (ODC) Metabolism of amino acids and derivatives
Drugs
Diseases
GWAS		Crohn's disease ( 21102463) Inflammatory bowel disease ( 23128233) Primary biliary cirrhosis ( 19458352 23000144 20639880) Rheumatoid arthritis ( 20453842) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Ulcerative colitis ( 21297633)
Protein-Protein Interactions		71 interactors: ABLIM3 AES AKAP9 AQP1 ARMC7 ARNT2 ATPAF2 BCAS2 BCL2L1 C1orf109 CABP5 CDKN1A CDKN2D CHCHD2 CHD3 DGCR6 EFHC1 EMC2 EXOC8 EXOSC5 FANCL FARS2 FBF1 GEM GRB2 HNRNPF HRAS IKZF1 IKZF4 IKZF5 ING5 KAT5 KRT19 LGALS14 LMO1 LMO2 MAGOHB MORN3 MRPL28 MRPL53 NATD1 NEK6 OAZ3 OSGIN1 PCID2 PFDN5 PIK3R2 PIN1 POLM POLR1C PPP1R16B PRKAA1 PRKAB2 PSMA1 RAD51D RBBP8 RCOR3 RHOA SPG21 STAMBPL1 STK16 STX11 TBC1D22B TCAF1 TEKT4 TRAPPC6A TRIM42 TSSK3 TSTD2 UBE2I ZGPAT	11 interactors: AZIN1 AZIN2 BLZF1 C1orf94 GGN IKZF3 L3MBTL3 OAZ1 ODC1 REL SMAD1
Entrez ID		22806	51686
HPRD ID		05869	18670
Ensembl ID			ENSG00000143450
Uniprot IDs		Q9UKT9	Q6GMR0 Q9UMX2
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Cell Cycle Process Mitotic Cell Cycle Process Organelle Organization Gene Expression Mitotic Cell Cycle Negative Regulation Of Cellular Metabolic Process Cellular Response To Stress Cellular Response To DNA Damage Stimulus Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Response To Radiation Regulation Of Cell Cycle Positive Regulation Of Metabolic Process Cellular Response To Organonitrogen Compound Response To Hormone Nucleobase-containing Compound Metabolic Process Cell Cycle Checkpoint RNA Metabolic Process Response To Ionizing Radiation Cell Cycle Arrest Regulation Of Signal Transduction Insulin Receptor Signaling Pathway Response To Organic Substance Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Mitotic Cell Cycle Immune System Process Response To Stress Nitrogen Compound Metabolic Process Signal Transduction In Response To DNA Damage Negative Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Hormone Stimulus Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Negative Regulation Of Cell Cycle Cellular Macromolecule Biosynthetic Process Transcription, DNA-templated Regulation Of Signaling Ammonium Transmembrane Transport Biosynthetic Process Macromolecule Biosynthetic Process Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Cellular Response To Organic Substance Response To Organonitrogen Compound	Polyamine Biosynthetic Process Amine Biosynthetic Process Polyamine Metabolic Process Cellular Biogenic Amine Metabolic Process Positive Regulation Of Polyamine Transmembrane Transport Amine Metabolic Process Ornithine Metabolic Process Regulation Of Protein Catabolic Process Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Trans-Golgi Network Membrane Organization Putrescine Biosynthetic Process From Ornithine Regulation Of Cellular Amino Acid Metabolic Process Putrescine Transport Agmatine Biosynthetic Process Regulation Of Cellular Ketone Metabolic Process Negative Regulation Of Protein Catabolic Process Regulation Of Protein Metabolic Process Putrescine Biosynthetic Process Mesoderm Development Negative Regulation Of Polyamine Transmembrane Transport Gamete Generation Primary MiRNA Processing Positive Regulation Of Transport Osteoblast Fate Commitment Sexual Reproduction Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Regulation Of Transcription From RNA Polymerase II Promoter SMAD Protein Complex Assembly Positive Regulation Of Interleukin-12 Biosynthetic Process Erythrocyte Maturation Alpha-amino Acid Metabolic Process Mesodermal Cell Fate Commitment Granulocyte Differentiation Kidney Development Regulation Of Interleukin-12 Biosynthetic Process Reproduction Renal System Development Positive Regulation Of Metabolic Process Macrophage Differentiation Cardiac Muscle Cell Proliferation Golgi To Plasma Membrane Protein Transport Production Of MiRNAs Involved In Gene Silencing By MiRNA Cellular Response To BMP Stimulus Urogenital System Development Regulation Of Cellular Process
Tagcloud ?		17q12 amplicon cab2 ccct darpp32 endued gc han haplotype histogenesis immumohistochemical implied per1 perld1 ppp1r1b q21 rs11869286 rs1877031 rs881844 rs9972882 sequenom signet stard3 steroidogenic tcap titin tma top2a znfn1a3	abundance affymetrix anxa2 arrays asthenozoospermia asthenozoospermic brd2 characterizing consider equal fertile hybridized implication infertile infertility microarrays motility project reach rnas sperm started subsequently teratozoospermic transcripts u133 utility validated version
Tagcloud (Difference) ?		17q12 amplicon cab2 ccct darpp32 endued gc han haplotype histogenesis immumohistochemical implied per1 perld1 ppp1r1b q21 rs11869286 rs1877031 rs881844 rs9972882 sequenom signet stard3 steroidogenic tcap titin tma top2a znfn1a3	abundance affymetrix anxa2 arrays asthenozoospermia asthenozoospermic brd2 characterizing consider equal fertile hybridized implication infertile infertility microarrays motility project reach rnas sperm started subsequently teratozoospermic transcripts u133 utility validated version
Tagcloud (Intersection) ?