KRT19 and ABI2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KRT19	ABI2
Gene Name		keratin 19, type I	abl-interactor 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Intermediate Filament Dystrophin-associated Glycoprotein Complex Z Disc Sarcolemma Costamere Extracellular Vesicular Exosome Cell Periphery	Cytoplasm Cytosol Cytoskeleton Lamellipodium Filopodium SCAR Complex
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Muscle Protein Complex Binding	DNA Binding Protein Binding Cytoskeletal Adaptor Activity SH3 Domain Binding Kinase Binding Ubiquitin Protein Ligase Binding Protein Complex Binding Rac GTPase Binding Proline-rich Region Binding
	Biological Process	Viral Process Response To Estrogen Sarcomere Organization Cell Differentiation Involved In Embryonic Placenta Development	Movement Of Cell Or Subcellular Component Cytoskeleton Organization Actin Polymerization Or Depolymerization Cell Migration Rac Protein Signal Transduction Peptidyl-tyrosine Phosphorylation Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways			Signaling by VEGF Fcgamma receptor (FCGR) dependent phagocytosis VEGFA-VEGFR2 Pathway Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS			Butyrylcholinesterase levels ( 21862451) Subclinical atherosclerosis traits (other) ( 17903303)
Protein-Protein Interactions		37 interactors: ABI2 AMOTL2 APC C10orf10 C1orf109 CARD9 CCDC146 CEP57L1 DGCR6L DMD EIF4E2 EIF4ENIF1 EXOC8 FAM107A FAM124B FANCG HAUS1 HGS IKZF3 KDM1A KIFC3 KRT15 KRT2 KRT6B PCM1 PLEKHA5 PNN POLR1C PPP1R18 SFI1 TBC1D7 TFPT TUBG1 UBE2I UCHL5 USHBP1 ZNF638	57 interactors: ABL1 ADAM19 AES ARHGAP32 ARMC7 BLOC1S6 CCDC102B CCDC36 CCDC53 CCHCR1 CDK6 CRX DTNB EFS EGLN3 EIF3H ENAH GCC1 HGS HNRNPK HOMER3 IFT20 KHDRBS1 KIAA1217 KIFC3 KRT13 KRT15 KRT19 KRT20 KRT31 KRT33B LMO2 MRFAP1L1 MRPL44 NCK2 NUP62 PCM1 PIN1 PPIF PRAM1 PRKAA1 PRKAA2 PRR16 SDCBP SH3KBP1 SNAP23 STAM2 TFIP11 TRAF3IP1 TRIM32 TRIP6 VARS2 VASP VCL VPS37C WASF2 WIPF1
Entrez ID		3880	10152
HPRD ID		01007	07338
Ensembl ID		ENSG00000171345	ENSG00000138443
Uniprot IDs		P08727	E9PEZ7 Q9NYB9
PDB IDs			2ED0 3P8C
Enriched GO Terms of Interacting Partners?		Cytoplasmic Microtubule Organization Organelle Organization Mitotic Cell Cycle Process Microtubule Cytoskeleton Organization Cell Cycle Process Mitotic Cell Cycle Microtubule-based Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition G2/M Transition Of Mitotic Cell Cycle Muscle Cell Cellular Homeostasis Cell Cycle Keratinocyte Activation Regulation Of Primitive Erythrocyte Differentiation Positive Regulation Of SUMO Transferase Activity Exocyst Assembly Microtubule Anchoring Nucleus Localization Negative Regulation Of Intracellular Signal Transduction Cytoskeleton Organization	Intracellular Transport Organelle Organization Cell Projection Assembly Establishment Of Localization In Cell Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Movement Of Cell Or Subcellular Component Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Signal Transduction Response To Stimulus Negative Regulation Of ERBB Signaling Pathway Negative Regulation Of Intracellular Signal Transduction Cytoskeleton Organization Negative Regulation Of Signaling Cellular Localization Cellular Component Assembly Regulation Of Signal Transduction Cell Projection Morphogenesis Cellular Response To Stimulus Developmental Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Surface Receptor Signaling Pathway Cell Part Morphogenesis Cell Cycle Arrest Cell Projection Organization Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Signaling Actin Cytoskeleton Organization System Development Actin Filament-based Process Anatomical Structure Development Signaling Intraciliary Transport Cell Morphogenesis Membrane Organization Generation Of Neurons Cell Communication Regulation Of Autophagy Enzyme Linked Receptor Protein Signaling Pathway Multicellular Organismal Development Protein Localization Protein Transport Neurogenesis Lamellipodium Assembly Signal Transduction Lamellipodium Organization Establishment Of Protein Localization Negative Regulation Of Cellular Senescence Microtubule-based Transport
Tagcloud ?		allograft biomarkers changed chronic clu cr diagnose differential difficult itraq latter lcn2 liver maldi olt option orthotopic predicting quantified re rejection reliable relt sixty tof transplantation treat understand unfortunately	aba abscisic arabidopsis aux1 auxin axr4 crosstalk ein2 eir1 elongation ethylene eto1 formed2 genotyping germination insensitive insensitive2 operate overproducer1 pin pin2 positional resistant1 resistant4 responsiveness root root1 seed thaliana
Tagcloud (Difference) ?		allograft biomarkers changed chronic clu cr diagnose differential difficult itraq latter lcn2 liver maldi olt option orthotopic predicting quantified re rejection reliable relt sixty tof transplantation treat understand unfortunately	aba abscisic arabidopsis aux1 auxin axr4 crosstalk ein2 eir1 elongation ethylene eto1 formed2 genotyping germination insensitive insensitive2 operate overproducer1 pin pin2 positional resistant1 resistant4 responsiveness root root1 seed thaliana
Tagcloud (Intersection) ?