IKZF3 and TSSK3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		IKZF3	TSSK3
Gene Name		IKAROS family zinc finger 3 (Aiolos)	testis-specific serine kinase 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Homodimerization Activity Sequence-specific DNA Binding Metal Ion Binding Protein Heterodimerization Activity	Magnesium Ion Binding Protein Serine/threonine Kinase Activity ATP Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Mesoderm Development Regulation Of B Cell Proliferation B Cell Activation Regulation Of Apoptotic Process Regulation Of B Cell Differentiation Regulation Of Lymphocyte Differentiation	Protein Phosphorylation Multicellular Organismal Development Spermatogenesis Regulation Of Signal Transduction Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 21102463) Inflammatory bowel disease ( 23128233) Primary biliary cirrhosis ( 19458352 23000144 20639880) Rheumatoid arthritis ( 20453842) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Ulcerative colitis ( 21297633)
Protein-Protein Interactions		71 interactors: ABLIM3 AES AKAP9 AQP1 ARMC7 ARNT2 ATPAF2 BCAS2 BCL2L1 C1orf109 CABP5 CDKN1A CDKN2D CHCHD2 CHD3 DGCR6 EFHC1 EMC2 EXOC8 EXOSC5 FANCL FARS2 FBF1 GEM GRB2 HNRNPF HRAS IKZF1 IKZF4 IKZF5 ING5 KAT5 KRT19 LGALS14 LMO1 LMO2 MAGOHB MORN3 MRPL28 MRPL53 NATD1 NEK6 OAZ3 OSGIN1 PCID2 PFDN5 PIK3R2 PIN1 POLM POLR1C PPP1R16B PRKAA1 PRKAB2 PSMA1 RAD51D RBBP8 RCOR3 RHOA SPG21 STAMBPL1 STK16 STX11 TBC1D22B TCAF1 TEKT4 TRAPPC6A TRIM42 TSSK3 TSTD2 UBE2I ZGPAT	18 interactors: ADAMTSL4 AES C15orf48 EFHC2 FUT9 GOLGA2 GP2 IKZF3 LNX1 OIP5 RBBP4 RBCK1 REL SMAD4 TCF4 TRIM9 VPS52 ZBTB25
Entrez ID		22806	81629
HPRD ID		05869	09635
Ensembl ID			ENSG00000162526
Uniprot IDs		Q9UKT9	Q96PN8
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Cell Cycle Process Mitotic Cell Cycle Process Organelle Organization Gene Expression Mitotic Cell Cycle Negative Regulation Of Cellular Metabolic Process Cellular Response To Stress Cellular Response To DNA Damage Stimulus Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Response To Radiation Regulation Of Cell Cycle Positive Regulation Of Metabolic Process Cellular Response To Organonitrogen Compound Response To Hormone Nucleobase-containing Compound Metabolic Process Cell Cycle Checkpoint RNA Metabolic Process Response To Ionizing Radiation Cell Cycle Arrest Regulation Of Signal Transduction Insulin Receptor Signaling Pathway Response To Organic Substance Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Mitotic Cell Cycle Immune System Process Response To Stress Nitrogen Compound Metabolic Process Signal Transduction In Response To DNA Damage Negative Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Hormone Stimulus Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Negative Regulation Of Cell Cycle Cellular Macromolecule Biosynthetic Process Transcription, DNA-templated Regulation Of Signaling Ammonium Transmembrane Transport Biosynthetic Process Macromolecule Biosynthetic Process Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Cellular Response To Organic Substance Response To Organonitrogen Compound	Regulation Of Binding Regulation Of Cell Death Positive Regulation Of Nucleocytoplasmic Transport Regulation Of Protein Binding Protein-DNA Complex Assembly CENP-A Containing Nucleosome Assembly Positive Regulation Of Intracellular Protein Transport Cellular Macromolecule Biosynthetic Process Positive Regulation Of Epithelial To Mesenchymal Transition Macromolecule Biosynthetic Process Fucosylation Histone Exchange DNA Replication-independent Nucleosome Assembly Regulation Of Nucleocytoplasmic Transport Transcription, DNA-templated Embryonic Digestive Tract Development RNA Biosynthetic Process Positive Regulation Of Intracellular Transport Centromere Complex Assembly Positive Regulation Of Stem Cell Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Epithelial To Mesenchymal Transition Regulation Of Intracellular Protein Transport Positive Regulation Of Cell Death Cellular Macromolecular Complex Assembly Negative Regulation Of Protein Binding Antigen Transcytosis By M Cells In Mucosal-associated Lymphoid Tissue Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis ATP-dependent Chromatin Remodeling Somatic Stem Cell Maintenance Negative Regulation Of Gene Expression Positive Regulation Of Protein Transport Nephrogenic Mesenchyme Morphogenesis Negative Regulation Of SNARE Complex Assembly Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Embryonic Ectodermal Digestive Tract Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of BMP Signaling Pathway Biosynthetic Process Positive Regulation Of Protein Import Into Nucleus Regulation Of Apoptotic Process Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Nephrogenic Mesenchyme Development Metanephric Mesenchyme Morphogenesis Protein Linear Polyubiquitination Negative Regulation Of Binding Positive Regulation Of Protein Localization To Nucleus Maintenance Of DNA Repeat Elements
Tagcloud ?		17q12 amplicon cab2 ccct darpp32 endued gc han haplotype histogenesis immumohistochemical implied per1 perld1 ppp1r1b q21 rs11869286 rs1877031 rs881844 rs9972882 sequenom signet stard3 steroidogenic tcap titin tma top2a znfn1a3
Tagcloud (Difference) ?		17q12 amplicon cab2 ccct darpp32 endued gc han haplotype histogenesis immumohistochemical implied per1 perld1 ppp1r1b q21 rs11869286 rs1877031 rs881844 rs9972882 sequenom signet stard3 steroidogenic tcap titin tma top2a znfn1a3
Tagcloud (Intersection) ?