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KRTAP10-3 and AQP1
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
KRTAP10-3
AQP1
Gene Name
keratin associated protein 10-3
aquaporin 1 (Colton blood group)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Keratin Filament
Nucleus
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Brush Border
Basal Plasma Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Symbiont-containing Vacuole
Symbiont-containing Vacuole Membrane
Brush Border Membrane
Nuclear Membrane
Sarcolemma
Axon Terminus
Apical Part Of Cell
Extracellular Vesicular Exosome
Molecular Function
Intracellular CGMP Activated Cation Channel Activity
Potassium Channel Activity
Water Transmembrane Transporter Activity
Protein Binding
Ammonium Transmembrane Transporter Activity
Potassium Ion Transmembrane Transporter Activity
Glycerol Transmembrane Transporter Activity
Water Channel Activity
Glycerol Channel Activity
Transmembrane Transporter Activity
Nitric Oxide Transmembrane Transporter Activity
Carbon Dioxide Transmembrane Transporter Activity
Ephrin Receptor Binding
Biological Process
Renal Water Homeostasis
Glomerular Filtration
Renal Water Transport
CGMP Biosynthetic Process
Potassium Ion Transport
Water Transport
Cell Volume Homeostasis
Cellular Water Homeostasis
Positive Regulation Of Lamellipodium Assembly
Positive Regulation Of Epithelial Cell Migration
Carbon Dioxide Transport
Ammonium Transport
Bicarbonate Transport
Glycerol Transport
Sensory Perception Of Pain
Cellular Homeostasis
Lateral Ventricle Development
Pancreatic Juice Secretion
Nitric Oxide Transport
Establishment Or Maintenance Of Actin Cytoskeleton Polarity
Cerebrospinal Fluid Secretion
Secretory Granule Organization
Cellular Response To Stress
Cellular Response To UV
Transepithelial Water Transport
Carbon Dioxide Transmembrane Transport
Wound Healing
Odontogenesis
Response To Drug
Hyperosmotic Salinity Response
Negative Regulation Of Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Response To Estrogen
Lipid Digestion
Small Molecule Metabolic Process
Positive Regulation Of Angiogenesis
Positive Regulation Of Saliva Secretion
Positive Regulation Of Fibroblast Proliferation
Camera-type Eye Morphogenesis
Multicellular Organismal Water Homeostasis
Corticotropin Secretion
Transmembrane Transport
Renal Water Absorption
Cellular Response To Hydrogen Peroxide
Cellular Response To Inorganic Substance
Cellular Response To Mechanical Stimulus
Cellular Response To Copper Ion
Cellular Response To Mercury Ion
Cellular Response To Retinoic Acid
Cellular Response To CAMP
Cellular Response To Hypoxia
Cellular Response To Salt Stress
Cellular Hyperosmotic Response
Cellular Response To Dexamethasone Stimulus
Cellular Response To Nitric Oxide
Potassium Ion Transmembrane Transport
Metanephric Descending Thin Limb Development
Metanephric Proximal Straight Tubule Development
Metanephric Proximal Convoluted Tubule Segment 2 Development
Metanephric Glomerulus Vasculature Development
Ammonium Transmembrane Transport
Maintenance Of Symbiont-containing Vacuole By Host
Cation Transmembrane Transport
Pathways
O2/CO2 exchange in erythrocytes
Erythrocytes take up carbon dioxide and release oxygen
Vasopressin regulates renal water homeostasis via Aquaporins
Passive transport by Aquaporins
Erythrocytes take up oxygen and release carbon dioxide
Aquaporin-mediated transport
Drugs
Acetazolamide
Diseases
GWAS
Nephrolithiasis (
22396660
)
Protein-Protein Interactions
288 interactors:
ACY3
ADAMTSL3
ADAMTSL4
ADAMTSL5
AEN
AES
ALDH3B1
ALPI
ALPP
AP1M1
AQP1
AREG
AVPI1
B4GALT7
BAHD1
BCL6B
BMP7
BMS1P5
BUD31
BYSL
C10orf62
C16orf59
C19orf57
C19orf66
C22orf39
C9orf9
CARD9
CARHSP1
CARKD
CATIP
CATSPER1
CBX2
CCDC26
CCER1
CD164
CD300A
CD300LG
CDK5R1
CERK
CHIC2
CHRD
CHRNG
CLDN2
CLK3
CLK4
COL8A1
CREB5
CST2
CST9L
CTNNBIP1
CTRC
CXCL16
DAAM2
DDX43
DDX6
DERL2
DHRS1
DHX57
DMRT3
DNAL4
DOCK2
EFNA3
EGFL8
FAM124B
FAM161A
FAM27E3
FAM71E2
FAM74A4
FAM76B
FARS2
FBXL18
FBXW5
FOXB1
FZD9
GABARAPL1
GATA2
GEM
GFOD1
GIP
GLIDR
GLIPR2
GLP1R
GLRX3
GNE
GNMT
GOLGA8EP
GPRIN2
GSTP1
GTF3C5
HBG1
HBZ
HHEX
HIST3H2A
HOXA1
HPCAL1
HSBP1
HSD3B7
HSPD1
HYAL2
IGSF8
IL2RG
INPP5D
IQUB
IWS1
JOSD1
KAT5
KCNK1
KIAA0040
KIF9
KLHL38
KLK15
KLK8
KRT83
KRTAP10-1
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP12-1
KRTAP13-1
KRTAP26-1
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-7
KRTAP5-6
KRTAP5-9
KRTAP9-2
LCE1B
LCE2A
LCE3C
LCE3E
LIMS2
LINC00636
LINC01588
LMF2
LMNA
LUZP4
LYVE1
MAPKBP1
MEOX2
MOBP
MPP3
MRPL40
MXI1
NAA10
NAB2
NDUFAF3
NID2
NLK
NOTCH2NL
NPBWR2
NPDC1
NPPB
NUBP2
NUDCD3
NUFIP2
OLFM2
OPCML
OTX1
P2RY6
PCED1A
PCSK5
PDE9A
PDIA5
PGAP2
PGLS
PIGS
PIN1
PKD2
PLSCR1
POLL
PPARD
PRKAA2
PRKAB2
PRKAG1
PRPF31
PTGDS
PTGER3
PTPMT1
PTPRH
PVR
PVRL2
PVRL3
QPRT
R3HDM2
RAB7A
RAMP3
RHNO1
RNF175
RPS19BP1
RPS28
RPUSD3
RTN4RL1
SCNM1
SDC3
SDCBP
SELM
SERF2
SLC15A3
SLC23A1
SLC25A10
SLC25A48
SLC35A2
SLC43A2
SLC6A20
SMCO4
SMCP
SMOC1
SNAI1
SNHG11
SPATA3
SPATA8
SPG7
SPINK2
SPRY1
SPRY2
STK16
TBC1D23
TCEB3
THAP10
THAP7
TINAGL1
TMEM106C
TMEM8A
TNFRSF6B
TNIP3
TNK2
TNP2
TNS2
TRIM42
TRPV6
TTC23
TXNDC5
TYMSOS
TYRO3
UCP2
UNC45A
UTP23
VPS11
WFDC10B
WIF1
WT1
XCL1
YIPF3
ZBTB24
ZBTB9
ZFYVE21
ZFYVE26
ZMYND10
ZNF101
ZNF124
ZNF136
ZNF138
ZNF155
ZNF165
ZNF20
ZNF202
ZNF23
ZNF250
ZNF26
ZNF264
ZNF266
ZNF32
ZNF417
ZNF433
ZNF439
ZNF446
ZNF461
ZNF490
ZNF559
ZNF564
ZNF572
ZNF578
ZNF581
ZNF587
ZNF625
ZNF670
ZNF679
ZNF697
ZNF699
ZNF763
ZNF786
ZNF79
ZNF792
ZNRF2P1
ZSCAN21
ZSCAN26
42 interactors:
ADAMTSL4
CCDC136
CCDC36
CCDC57
CCDC85B
CEP44
CRTAC1
CSRNP1
EFEMP2
EPHB2
FOS
FSD2
IKZF2
IKZF3
KCTD17
KCTD9
KIAA1958
KRT31
KRT33B
KRT40
KRTAP10-3
KRTAP10-7
KRTAP4-12
KRTAP4-2
KRTAP9-2
MDFI
MID2
MTUS2
NBPF22P
NOTCH2NL
PICK1
RGS17
RGS20
RIMBP3
SIAH1
SPRY2
TCF4
TNK2
TRAF1
TRAF2
TRIM23
TRIP6
Entrez ID
386682
358
HPRD ID
11189
00140
Ensembl ID
ENSG00000240583
Uniprot IDs
P60369
B4DPF5
B4E3E3
P29972
PDB IDs
1FQY
1H6I
1IH5
Enriched GO Terms of Interacting Partners
?
Transcription, DNA-templated
RNA Biosynthetic Process
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Gene Expression
Cellular Nitrogen Compound Metabolic Process
Macromolecule Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Nitrogen Compound Metabolic Process
Biosynthetic Process
Regulation Of Transcription, DNA-templated
Regulation Of RNA Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Cellular Process
Cellular Process
Cellular Metabolic Process
Regulation Of Metabolic Process
Positive Regulation Of Immune Response To Tumor Cell
Developmental Process
Susceptibility To T Cell Mediated Cytotoxicity
Negative Regulation Of MAP Kinase Activity
Pattern Specification Process
Transepithelial Transport
Negative Regulation Of Cell Proliferation
Fertilization
Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Protein Serine/threonine Kinase Activity
Negative Regulation Of Glomerular Mesangial Cell Proliferation
Fusion Of Virus Membrane With Host Plasma Membrane
Negative Regulation Of Glomerulus Development
Positive Regulation Of Urine Volume
Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Serine Phosphorylation Of STAT3 Protein
Negative Regulation Of Signal Transduction
Organ Development
Multicellular Organismal Development
Negative Regulation Of Transcription, DNA-templated
Branching Morphogenesis Of An Epithelial Tube
Negative Regulation Of MAPK Cascade
Metanephric Mesenchyme Development
Negative Regulation Of Signaling
Urogenital System Development
Keratinization
Regulation Of Cell Motility
Negative Regulation Of Nucleic Acid-templated Transcription
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Signaling
Positive Regulation Of Metabolic Process
Regulation Of Metabolic Process
Regulation Of Binding
Developmental Process
Regulation Of Gene Expression
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Dendritic Spine Organization
Positive Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of Signal Transduction
Axonal Fasciculation
Embryonic Organ Morphogenesis
Regulation Of Signal Transduction
Signal Transduction
Regulation Of Protein Binding
Cell Differentiation
Regulation Of Cellular Process
Face Morphogenesis
Neuron Recognition
Regulation Of Apoptotic Process
Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Head Morphogenesis
Regulation Of Nitrogen Compound Metabolic Process
Signaling
Regulation Of Cell Death
Positive Regulation Of Cellular Metabolic Process
Regulation Of Extrinsic Apoptotic Signaling Pathway
Cell Communication
Negative Regulation Of Signaling
Face Development
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Nucleocytoplasmic Transport
Cellular Response To Extracellular Stimulus
Embryonic Organ Development
I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Fat Cell Differentiation
Body Morphogenesis
DNA Methylation
TRIF-dependent Toll-like Receptor Signaling Pathway
Catenin Import Into Nucleus
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Regulation Of Intracellular Signal Transduction
Termination Of G-protein Coupled Receptor Signaling Pathway
Positive Regulation Of Protein Binding
MyD88-independent Toll-like Receptor Signaling Pathway
Termination Of Signal Transduction
Toll-like Receptor 3 Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Tagcloud
?
2cl
absorption
acclimation
bumetanide
circuit
cl
cotransporter
eel
exchanger
gn
governed
guanylin
hco3
intestine
isc
mi
ncc
nccbeta
nkcc
nkcc2beta
nullified
player
remainder
seawater
slc26a6
teleost
transporters
versa
vice
Tagcloud (Difference)
?
2cl
absorption
acclimation
bumetanide
circuit
cl
cotransporter
eel
exchanger
gn
governed
guanylin
hco3
intestine
isc
mi
ncc
nccbeta
nkcc
nkcc2beta
nullified
player
remainder
seawater
slc26a6
teleost
transporters
versa
vice
Tagcloud (Intersection)
?