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KRTAP10-3 and PCSK5
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
KRTAP10-3
PCSK5
Gene Name
keratin associated protein 10-3
proprotein convertase subtilisin/kexin type 5
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Keratin Filament
Extracellular Space
Golgi Apparatus
Golgi Lumen
Integral Component Of Membrane
Secretory Granule
Molecular Function
Serine-type Endopeptidase Activity
Peptidase Activity
Peptide Binding
Biological Process
Kidney Development
Renin Secretion Into Blood Stream
Signal Peptide Processing
Proteolysis
Cell-cell Signaling
Heart Development
Embryo Implantation
Anterior/posterior Pattern Specification
Protein Processing
Peptide Hormone Processing
Viral Life Cycle
Respiratory Tube Development
Nerve Growth Factor Processing
Limb Morphogenesis
Cytokine Biosynthetic Process
Peptide Biosynthetic Process
Neurotrophin TRK Receptor Signaling Pathway
Embryonic Digestive Tract Development
Embryonic Skeletal System Development
Pathways
Signalling by NGF
NGF processing
Drugs
Diseases
GWAS
Amyotrophic lateral sclerosis (age of onset) (
22959728
)
Height (
20881960
23563607
)
Metabolite levels (5-HIAA) (
23319000
)
Response to fenofibrate (adiponectin levels) (
23149075
)
Total ventricular volume (
21116278
)
Protein-Protein Interactions
288 interactors:
ACY3
ADAMTSL3
ADAMTSL4
ADAMTSL5
AEN
AES
ALDH3B1
ALPI
ALPP
AP1M1
AQP1
AREG
AVPI1
B4GALT7
BAHD1
BCL6B
BMP7
BMS1P5
BUD31
BYSL
C10orf62
C16orf59
C19orf57
C19orf66
C22orf39
C9orf9
CARD9
CARHSP1
CARKD
CATIP
CATSPER1
CBX2
CCDC26
CCER1
CD164
CD300A
CD300LG
CDK5R1
CERK
CHIC2
CHRD
CHRNG
CLDN2
CLK3
CLK4
COL8A1
CREB5
CST2
CST9L
CTNNBIP1
CTRC
CXCL16
DAAM2
DDX43
DDX6
DERL2
DHRS1
DHX57
DMRT3
DNAL4
DOCK2
EFNA3
EGFL8
FAM124B
FAM161A
FAM27E3
FAM71E2
FAM74A4
FAM76B
FARS2
FBXL18
FBXW5
FOXB1
FZD9
GABARAPL1
GATA2
GEM
GFOD1
GIP
GLIDR
GLIPR2
GLP1R
GLRX3
GNE
GNMT
GOLGA8EP
GPRIN2
GSTP1
GTF3C5
HBG1
HBZ
HHEX
HIST3H2A
HOXA1
HPCAL1
HSBP1
HSD3B7
HSPD1
HYAL2
IGSF8
IL2RG
INPP5D
IQUB
IWS1
JOSD1
KAT5
KCNK1
KIAA0040
KIF9
KLHL38
KLK15
KLK8
KRT83
KRTAP10-1
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP12-1
KRTAP13-1
KRTAP26-1
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-7
KRTAP5-6
KRTAP5-9
KRTAP9-2
LCE1B
LCE2A
LCE3C
LCE3E
LIMS2
LINC00636
LINC01588
LMF2
LMNA
LUZP4
LYVE1
MAPKBP1
MEOX2
MOBP
MPP3
MRPL40
MXI1
NAA10
NAB2
NDUFAF3
NID2
NLK
NOTCH2NL
NPBWR2
NPDC1
NPPB
NUBP2
NUDCD3
NUFIP2
OLFM2
OPCML
OTX1
P2RY6
PCED1A
PCSK5
PDE9A
PDIA5
PGAP2
PGLS
PIGS
PIN1
PKD2
PLSCR1
POLL
PPARD
PRKAA2
PRKAB2
PRKAG1
PRPF31
PTGDS
PTGER3
PTPMT1
PTPRH
PVR
PVRL2
PVRL3
QPRT
R3HDM2
RAB7A
RAMP3
RHNO1
RNF175
RPS19BP1
RPS28
RPUSD3
RTN4RL1
SCNM1
SDC3
SDCBP
SELM
SERF2
SLC15A3
SLC23A1
SLC25A10
SLC25A48
SLC35A2
SLC43A2
SLC6A20
SMCO4
SMCP
SMOC1
SNAI1
SNHG11
SPATA3
SPATA8
SPG7
SPINK2
SPRY1
SPRY2
STK16
TBC1D23
TCEB3
THAP10
THAP7
TINAGL1
TMEM106C
TMEM8A
TNFRSF6B
TNIP3
TNK2
TNP2
TNS2
TRIM42
TRPV6
TTC23
TXNDC5
TYMSOS
TYRO3
UCP2
UNC45A
UTP23
VPS11
WFDC10B
WIF1
WT1
XCL1
YIPF3
ZBTB24
ZBTB9
ZFYVE21
ZFYVE26
ZMYND10
ZNF101
ZNF124
ZNF136
ZNF138
ZNF155
ZNF165
ZNF20
ZNF202
ZNF23
ZNF250
ZNF26
ZNF264
ZNF266
ZNF32
ZNF417
ZNF433
ZNF439
ZNF446
ZNF461
ZNF490
ZNF559
ZNF564
ZNF572
ZNF578
ZNF581
ZNF587
ZNF625
ZNF670
ZNF679
ZNF697
ZNF699
ZNF763
ZNF786
ZNF79
ZNF792
ZNRF2P1
ZSCAN21
ZSCAN26
20 interactors:
AMH
APPBP2
ATN1
CACNA1A
GLRX3
HOXA1
ITGA6
KRTAP10-3
KRTAP10-7
KRTAP10-8
KRTAP4-12
KRTAP5-9
LCE3C
MEOX2
NOTCH2NL
NUFIP2
PMCH
PTPRM
REN
STK16
Entrez ID
386682
5125
HPRD ID
11189
08985
Ensembl ID
ENSG00000099139
Uniprot IDs
P60369
Q92824
PDB IDs
Enriched GO Terms of Interacting Partners
?
Transcription, DNA-templated
RNA Biosynthetic Process
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Gene Expression
Cellular Nitrogen Compound Metabolic Process
Macromolecule Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Nitrogen Compound Metabolic Process
Biosynthetic Process
Regulation Of Transcription, DNA-templated
Regulation Of RNA Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Cellular Process
Cellular Process
Cellular Metabolic Process
Regulation Of Metabolic Process
Positive Regulation Of Immune Response To Tumor Cell
Developmental Process
Susceptibility To T Cell Mediated Cytotoxicity
Negative Regulation Of MAP Kinase Activity
Pattern Specification Process
Transepithelial Transport
Negative Regulation Of Cell Proliferation
Fertilization
Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Protein Serine/threonine Kinase Activity
Negative Regulation Of Glomerular Mesangial Cell Proliferation
Fusion Of Virus Membrane With Host Plasma Membrane
Negative Regulation Of Glomerulus Development
Positive Regulation Of Urine Volume
Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Serine Phosphorylation Of STAT3 Protein
Negative Regulation Of Signal Transduction
Organ Development
Multicellular Organismal Development
Negative Regulation Of Transcription, DNA-templated
Branching Morphogenesis Of An Epithelial Tube
Negative Regulation Of MAPK Cascade
Metanephric Mesenchyme Development
Negative Regulation Of Signaling
Urogenital System Development
Keratinization
Regulation Of Cell Motility
Negative Regulation Of Nucleic Acid-templated Transcription
Developmental Process
Multicellular Organismal Development
Pons Development
Cell Differentiation
Anatomical Structure Development
Organ Development
System Development
Tissue Development
Behavior
Neural Nucleus Development
Optokinetic Behavior
Cerebellar Molecular Layer Development
Abducens Nerve Formation
Neuron Death
Vestibular Nucleus Development
Facial Nucleus Development
Preantral Ovarian Follicle Growth
Urogenital System Development
Feeding Behavior
Positive Regulation Of Gene Expression
Rhombomere 4 Development
Cerebellum Maturation
Semicircular Canal Formation
Musculoskeletal Movement, Spinal Reflex Action
Anatomical Structure Morphogenesis
Rhombomere 3 Development
Rhombomere 5 Development
Gamma-aminobutyric Acid Secretion
Renin-angiotensin Regulation Of Aldosterone Production
Metencephalon Development
Neuromuscular Process
Regulation Of Acetylcholine Secretion, Neurotransmission
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Anatomical Structure Formation Involved In Morphogenesis
Response To Drug
Rhythmic Synaptic Transmission
Somite Specification
Ectodermal Cell Differentiation
Cell Development
Response To External Stimulus
Regulation Of Transcription From RNA Polymerase II Promoter
Oogenesis Stage
Cell Projection Organization
Drinking Behavior
Gonadal Mesoderm Development
Response To CGMP
Mullerian Duct Regression
Hindbrain Development
Cell Morphogenesis Involved In Neuron Differentiation
Calcium Ion-dependent Exocytosis Of Neurotransmitter
Tagcloud
?
angptl2
cldn10
cldn4
cst6
dioestrus
enpp1
epas1
itgb4
lgals1
lgals3bp
maged1
mep1b
metoestrus
muc16
oestrogens
oestrous
oestrus
plat
preoestrus
sepp1
simmental
slc11a2
slc16a1
slc1a1
tdgf1
tek
timp1
timp2
tjp1
Tagcloud (Difference)
?
angptl2
cldn10
cldn4
cst6
dioestrus
enpp1
epas1
itgb4
lgals1
lgals3bp
maged1
mep1b
metoestrus
muc16
oestrogens
oestrous
oestrus
plat
preoestrus
sepp1
simmental
slc11a2
slc16a1
slc1a1
tdgf1
tek
timp1
timp2
tjp1
Tagcloud (Intersection)
?