KRTAP10-3 and CDK5R1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KRTAP10-3	CDK5R1
Gene Name		keratin associated protein 10-3	cyclin-dependent kinase 5, regulatory subunit 1 (p35)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Keratin Filament	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Membrane Cyclin-dependent Protein Kinase 5 Holoenzyme Complex Axon Dendrite Growth Cone Neuromuscular Junction Neuronal Cell Body Dendritic Spine Intracellular Membrane-bounded Organelle Contractile Fiber Perinuclear Region Of Cytoplasm
	Molecular Function		Protein Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Calcium Ion Binding Protein Binding Kinase Activity Cyclin-dependent Protein Kinase 5 Activator Activity Protein Kinase Binding Protein Serine/threonine Kinase Activator Activity Cadherin Binding Ephrin Receptor Binding
	Biological Process		Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Neuron Migration Neuron Cell-cell Adhesion G-protein Coupled Acetylcholine Receptor Signaling Pathway Axon Guidance Axonal Fasciculation Brain Development Cell Proliferation Embryo Development Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Cerebellum Development Superior Olivary Nucleus Maturation Hippocampus Development Layer Formation In Cerebral Cortex Neuron Differentiation Negative Regulation Of Axon Extension Neuron Projection Development Regulation Of Actin Cytoskeleton Organization Serine Phosphorylation Of STAT3 Protein Ionotropic Glutamate Receptor Signaling Pathway Positive Regulation Of Neuron Apoptotic Process Regulation Of Neuron Differentiation Negative Regulation Of Transcription, DNA-templated Ephrin Receptor Signaling Pathway Rhythmic Process Regulation Of Dendritic Spine Morphogenesis Regulation Of Microtubule Cytoskeleton Organization Positive Regulation Of Cell Cycle Arrest Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Protein Targeting To Membrane
Pathways			Axon guidance Semaphorin interactions CRMPs in Sema3A signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions		288 interactors: ACY3 ADAMTSL3 ADAMTSL4 ADAMTSL5 AEN AES ALDH3B1 ALPI ALPP AP1M1 AQP1 AREG AVPI1 B4GALT7 BAHD1 BCL6B BMP7 BMS1P5 BUD31 BYSL C10orf62 C16orf59 C19orf57 C19orf66 C22orf39 C9orf9 CARD9 CARHSP1 CARKD CATIP CATSPER1 CBX2 CCDC26 CCER1 CD164 CD300A CD300LG CDK5R1 CERK CHIC2 CHRD CHRNG CLDN2 CLK3 CLK4 COL8A1 CREB5 CST2 CST9L CTNNBIP1 CTRC CXCL16 DAAM2 DDX43 DDX6 DERL2 DHRS1 DHX57 DMRT3 DNAL4 DOCK2 EFNA3 EGFL8 FAM124B FAM161A FAM27E3 FAM71E2 FAM74A4 FAM76B FARS2 FBXL18 FBXW5 FOXB1 FZD9 GABARAPL1 GATA2 GEM GFOD1 GIP GLIDR GLIPR2 GLP1R GLRX3 GNE GNMT GOLGA8EP GPRIN2 GSTP1 GTF3C5 HBG1 HBZ HHEX HIST3H2A HOXA1 HPCAL1 HSBP1 HSD3B7 HSPD1 HYAL2 IGSF8 IL2RG INPP5D IQUB IWS1 JOSD1 KAT5 KCNK1 KIAA0040 KIF9 KLHL38 KLK15 KLK8 KRT83 KRTAP10-1 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP13-1 KRTAP26-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 LCE1B LCE2A LCE3C LCE3E LIMS2 LINC00636 LINC01588 LMF2 LMNA LUZP4 LYVE1 MAPKBP1 MEOX2 MOBP MPP3 MRPL40 MXI1 NAA10 NAB2 NDUFAF3 NID2 NLK NOTCH2NL NPBWR2 NPDC1 NPPB NUBP2 NUDCD3 NUFIP2 OLFM2 OPCML OTX1 P2RY6 PCED1A PCSK5 PDE9A PDIA5 PGAP2 PGLS PIGS PIN1 PKD2 PLSCR1 POLL PPARD PRKAA2 PRKAB2 PRKAG1 PRPF31 PTGDS PTGER3 PTPMT1 PTPRH PVR PVRL2 PVRL3 QPRT R3HDM2 RAB7A RAMP3 RHNO1 RNF175 RPS19BP1 RPS28 RPUSD3 RTN4RL1 SCNM1 SDC3 SDCBP SELM SERF2 SLC15A3 SLC23A1 SLC25A10 SLC25A48 SLC35A2 SLC43A2 SLC6A20 SMCO4 SMCP SMOC1 SNAI1 SNHG11 SPATA3 SPATA8 SPG7 SPINK2 SPRY1 SPRY2 STK16 TBC1D23 TCEB3 THAP10 THAP7 TINAGL1 TMEM106C TMEM8A TNFRSF6B TNIP3 TNK2 TNP2 TNS2 TRIM42 TRPV6 TTC23 TXNDC5 TYMSOS TYRO3 UCP2 UNC45A UTP23 VPS11 WFDC10B WIF1 WT1 XCL1 YIPF3 ZBTB24 ZBTB9 ZFYVE21 ZFYVE26 ZMYND10 ZNF101 ZNF124 ZNF136 ZNF138 ZNF155 ZNF165 ZNF20 ZNF202 ZNF23 ZNF250 ZNF26 ZNF264 ZNF266 ZNF32 ZNF417 ZNF433 ZNF439 ZNF446 ZNF461 ZNF490 ZNF559 ZNF564 ZNF572 ZNF578 ZNF581 ZNF587 ZNF625 ZNF670 ZNF679 ZNF697 ZNF699 ZNF763 ZNF786 ZNF79 ZNF792 ZNRF2P1 ZSCAN21 ZSCAN26	31 interactors: ACTN1 AMPH APP BLOC1S6 CAMK2A CAPN1 CAPN2 CDK16 CDK5 CDK5RAP1 CDK5RAP2 CDK5RAP3 CDK9 CHN1 CTNNB1 HSP90AA1 KRT40 KRTAP10-3 LMTK2 MAPT MTUS2 NEDD4 NES NOTCH2NL ODF1 PAK1 SET SIAH1 STXBP1 TSC22D4 TTBK1
Entrez ID		386682	8851
HPRD ID		11189	04586
Ensembl ID			ENSG00000176749
Uniprot IDs		P60369	Q15078 Q8N619
PDB IDs			1H4L 1UNG 1UNH 1UNL 3O0G
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Expression Cellular Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Cellular Process Cellular Process Cellular Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Immune Response To Tumor Cell Developmental Process Susceptibility To T Cell Mediated Cytotoxicity Negative Regulation Of MAP Kinase Activity Pattern Specification Process Transepithelial Transport Negative Regulation Of Cell Proliferation Fertilization Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Glomerular Mesangial Cell Proliferation Fusion Of Virus Membrane With Host Plasma Membrane Negative Regulation Of Glomerulus Development Positive Regulation Of Urine Volume Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Serine Phosphorylation Of STAT3 Protein Negative Regulation Of Signal Transduction Organ Development Multicellular Organismal Development Negative Regulation Of Transcription, DNA-templated Branching Morphogenesis Of An Epithelial Tube Negative Regulation Of MAPK Cascade Metanephric Mesenchyme Development Negative Regulation Of Signaling Urogenital System Development Keratinization Regulation Of Cell Motility Negative Regulation Of Nucleic Acid-templated Transcription	Generation Of Neurons Nervous System Development Neurogenesis Establishment Of Localization In Cell Neuron Projection Development Cellular Localization Neuron Differentiation Cell Differentiation Cell Projection Organization Neuron Development Multicellular Organismal Development Vesicle-mediated Transport Regulation Of Organelle Organization Regulation Of Neurogenesis Establishment Of Organelle Localization Regulation Of Cellular Component Organization Developmental Process Cell Morphogenesis Involved In Differentiation Exocytosis Axonogenesis Synaptic Vesicle Transport Regulation Of Neuron Differentiation Cell Morphogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Cell Projection Morphogenesis Cell Development Regulation Of Cell Development System Development Cell Part Morphogenesis Organelle Localization Neuron Projection Morphogenesis Receptor Catabolic Process Anatomical Structure Development Synapse Organization Regulation Of Cytoskeleton Organization Secretion By Cell Brain Development Receptor Metabolic Process Response To Abiotic Stimulus Head Development Establishment Of Vesicle Localization Negative Regulation Of Neuron Death Vesicle Localization Axon Guidance Regulation Of Cell Differentiation Secretion Anatomical Structure Morphogenesis Regulation Of Cell Cycle Locomotion
Tagcloud ?			10a 200c 30a 30c arhgap5 cd36 cdh2 chips cyp27b1 figure gemcitabine gna13 gp5 hist1h2bf hlf igsf3 ikbkb il32 intriguing mirs nrp2 oxidoreductase pak7 putatively rab23 rap2a slc11a1 sod3 tp53i3
Tagcloud (Difference) ?			10a 200c 30a 30c arhgap5 cd36 cdh2 chips cyp27b1 figure gemcitabine gna13 gp5 hist1h2bf hlf igsf3 ikbkb il32 intriguing mirs nrp2 oxidoreductase pak7 putatively rab23 rap2a slc11a1 sod3 tp53i3
Tagcloud (Intersection) ?