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KRTAP10-3 and QPRT
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
KRTAP10-3
QPRT
Gene Name
keratin associated protein 10-3
quinolinate phosphoribosyltransferase
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Keratin Filament
Cytoplasm
Cytosol
Extracellular Vesicular Exosome
Molecular Function
Nicotinate-nucleotide Diphosphorylase (carboxylating) Activity
Protein Homodimerization Activity
Biological Process
Vitamin Metabolic Process
Water-soluble Vitamin Metabolic Process
NAD Biosynthetic Process
NAD Metabolic Process
Quinolinate Catabolic Process
Small Molecule Metabolic Process
Protein Oligomerization
Pathways
Metabolism of vitamins and cofactors
Defective GIF causes intrinsic factor deficiency
Defective CD320 causes methylmalonic aciduria
Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF
Defective HLCS causes multiple carboxylase deficiency
Defective MMAB causes methylmalonic aciduria type cblB
Defective BTD causes biotidinase deficiency
Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC
Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD
Defective MTR causes methylmalonic aciduria and homocystinuria type cblG
Defective MMAA causes methylmalonic aciduria type cblA
Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE
Defective CUBN causes hereditary megaloblastic anemia 1
Defective AMN causes hereditary megaloblastic anemia 1
Defective MUT causes methylmalonic aciduria mut type
Metabolism of water-soluble vitamins and cofactors
Defects in biotin (Btn) metabolism
Defective TCN2 causes hereditary megaloblastic anemia
Nicotinate metabolism
Defects in vitamin and cofactor metabolism
Defects in cobalamin (B12) metabolism
Drugs
Niacin
Diseases
GWAS
Protein-Protein Interactions
288 interactors:
ACY3
ADAMTSL3
ADAMTSL4
ADAMTSL5
AEN
AES
ALDH3B1
ALPI
ALPP
AP1M1
AQP1
AREG
AVPI1
B4GALT7
BAHD1
BCL6B
BMP7
BMS1P5
BUD31
BYSL
C10orf62
C16orf59
C19orf57
C19orf66
C22orf39
C9orf9
CARD9
CARHSP1
CARKD
CATIP
CATSPER1
CBX2
CCDC26
CCER1
CD164
CD300A
CD300LG
CDK5R1
CERK
CHIC2
CHRD
CHRNG
CLDN2
CLK3
CLK4
COL8A1
CREB5
CST2
CST9L
CTNNBIP1
CTRC
CXCL16
DAAM2
DDX43
DDX6
DERL2
DHRS1
DHX57
DMRT3
DNAL4
DOCK2
EFNA3
EGFL8
FAM124B
FAM161A
FAM27E3
FAM71E2
FAM74A4
FAM76B
FARS2
FBXL18
FBXW5
FOXB1
FZD9
GABARAPL1
GATA2
GEM
GFOD1
GIP
GLIDR
GLIPR2
GLP1R
GLRX3
GNE
GNMT
GOLGA8EP
GPRIN2
GSTP1
GTF3C5
HBG1
HBZ
HHEX
HIST3H2A
HOXA1
HPCAL1
HSBP1
HSD3B7
HSPD1
HYAL2
IGSF8
IL2RG
INPP5D
IQUB
IWS1
JOSD1
KAT5
KCNK1
KIAA0040
KIF9
KLHL38
KLK15
KLK8
KRT83
KRTAP10-1
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP12-1
KRTAP13-1
KRTAP26-1
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-7
KRTAP5-6
KRTAP5-9
KRTAP9-2
LCE1B
LCE2A
LCE3C
LCE3E
LIMS2
LINC00636
LINC01588
LMF2
LMNA
LUZP4
LYVE1
MAPKBP1
MEOX2
MOBP
MPP3
MRPL40
MXI1
NAA10
NAB2
NDUFAF3
NID2
NLK
NOTCH2NL
NPBWR2
NPDC1
NPPB
NUBP2
NUDCD3
NUFIP2
OLFM2
OPCML
OTX1
P2RY6
PCED1A
PCSK5
PDE9A
PDIA5
PGAP2
PGLS
PIGS
PIN1
PKD2
PLSCR1
POLL
PPARD
PRKAA2
PRKAB2
PRKAG1
PRPF31
PTGDS
PTGER3
PTPMT1
PTPRH
PVR
PVRL2
PVRL3
QPRT
R3HDM2
RAB7A
RAMP3
RHNO1
RNF175
RPS19BP1
RPS28
RPUSD3
RTN4RL1
SCNM1
SDC3
SDCBP
SELM
SERF2
SLC15A3
SLC23A1
SLC25A10
SLC25A48
SLC35A2
SLC43A2
SLC6A20
SMCO4
SMCP
SMOC1
SNAI1
SNHG11
SPATA3
SPATA8
SPG7
SPINK2
SPRY1
SPRY2
STK16
TBC1D23
TCEB3
THAP10
THAP7
TINAGL1
TMEM106C
TMEM8A
TNFRSF6B
TNIP3
TNK2
TNP2
TNS2
TRIM42
TRPV6
TTC23
TXNDC5
TYMSOS
TYRO3
UCP2
UNC45A
UTP23
VPS11
WFDC10B
WIF1
WT1
XCL1
YIPF3
ZBTB24
ZBTB9
ZFYVE21
ZFYVE26
ZMYND10
ZNF101
ZNF124
ZNF136
ZNF138
ZNF155
ZNF165
ZNF20
ZNF202
ZNF23
ZNF250
ZNF26
ZNF264
ZNF266
ZNF32
ZNF417
ZNF433
ZNF439
ZNF446
ZNF461
ZNF490
ZNF559
ZNF564
ZNF572
ZNF578
ZNF581
ZNF587
ZNF625
ZNF670
ZNF679
ZNF697
ZNF699
ZNF763
ZNF786
ZNF79
ZNF792
ZNRF2P1
ZSCAN21
ZSCAN26
7 interactors:
GIT2
KRT40
KRTAP10-3
KRTAP10-8
KRTAP4-12
NOTCH2NL
SUFU
Entrez ID
386682
23475
HPRD ID
11189
06950
Ensembl ID
Uniprot IDs
P60369
Q15274
PDB IDs
2JBM
3LAR
4KWV
4KWW
Enriched GO Terms of Interacting Partners
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Transcription, DNA-templated
RNA Biosynthetic Process
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Gene Expression
Cellular Nitrogen Compound Metabolic Process
Macromolecule Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Nitrogen Compound Metabolic Process
Biosynthetic Process
Regulation Of Transcription, DNA-templated
Regulation Of RNA Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Cellular Process
Cellular Process
Cellular Metabolic Process
Regulation Of Metabolic Process
Positive Regulation Of Immune Response To Tumor Cell
Developmental Process
Susceptibility To T Cell Mediated Cytotoxicity
Negative Regulation Of MAP Kinase Activity
Pattern Specification Process
Transepithelial Transport
Negative Regulation Of Cell Proliferation
Fertilization
Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Protein Serine/threonine Kinase Activity
Negative Regulation Of Glomerular Mesangial Cell Proliferation
Fusion Of Virus Membrane With Host Plasma Membrane
Negative Regulation Of Glomerulus Development
Positive Regulation Of Urine Volume
Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Serine Phosphorylation Of STAT3 Protein
Negative Regulation Of Signal Transduction
Organ Development
Multicellular Organismal Development
Negative Regulation Of Transcription, DNA-templated
Branching Morphogenesis Of An Epithelial Tube
Negative Regulation Of MAPK Cascade
Metanephric Mesenchyme Development
Negative Regulation Of Signaling
Urogenital System Development
Keratinization
Regulation Of Cell Motility
Negative Regulation Of Nucleic Acid-templated Transcription
Smoothened Signaling Pathway Involved In Spinal Cord Motor Neuron Cell Fate Specification
Smoothened Signaling Pathway Involved In Ventral Spinal Cord Interneuron Specification
Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning
Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning
Negative Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Ventral Spinal Cord Interneuron Specification
Spinal Cord Motor Neuron Cell Fate Specification
Ventral Spinal Cord Interneuron Fate Commitment
Ventral Spinal Cord Interneuron Differentiation
Cytoplasmic Sequestering Of Transcription Factor
Behavioral Response To Pain
Cytoplasmic Sequestering Of Protein
Negative Regulation Of Embryonic Development
Spinal Cord Dorsal/ventral Patterning
Neuron Fate Specification
Negative Regulation Of Smoothened Signaling Pathway
Spinal Cord Patterning
Response To Pain
Spinal Cord Motor Neuron Differentiation
Negative Regulation Of Osteoblast Differentiation
Negative Regulation Of Transcription Factor Import Into Nucleus
Ventral Spinal Cord Development
Heart Looping
Determination Of Heart Left/right Asymmetry
Cell Differentiation In Spinal Cord
Embryonic Heart Tube Morphogenesis
Negative Regulation Of Protein Import Into Nucleus
Regulation Of ARF GTPase Activity
Negative Regulation Of Cellular Protein Catabolic Process
Negative Regulation Of Ossification
Neuron Fate Commitment
Negative Regulation Of Protein Localization To Nucleus
Embryonic Heart Tube Development
Negative Regulation Of Intracellular Protein Transport
Multicellular Organismal Response To Stress
Regulation Of Transcription Factor Import Into Nucleus
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Cell Fate Specification
Regulation Of Smoothened Signaling Pathway
Regulation Of ARF Protein Signal Transduction
Negative Regulation Of Protein Ubiquitination
Neural Tube Closure
Spinal Cord Development
Determination Of Left/right Symmetry
Determination Of Bilateral Symmetry
Regulation Of Embryonic Development
Negative Regulation Of Intracellular Transport
Smoothened Signaling Pathway
Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Negative Regulation Of Protein Catabolic Process
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