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KLC1 and PTGER4
Number of citations of the paper that reports this interaction (PubMedID
28298427
)
90
Data Source:
BioGRID
(two hybrid)
KLC1
PTGER4
Description
kinesin light chain 1
prostaglandin E receptor 4
Image
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Cytoskeleton
Kinesin Complex
Microtubule
Membrane
Growth Cone
Cytoplasmic Vesicle
Cell Projection
Plasma Membrane
Membrane
Molecular Function
Cytoskeletal Motor Activity
Protein Binding
Kinesin Binding
G Protein-coupled Receptor Activity
Prostaglandin Receptor Activity
Prostaglandin E Receptor Activity
Protein Binding
Biological Process
Microtubule-based Movement
Cell Adhesion
Stress Granule Disassembly
MAPK Cascade
Negative Regulation Of Cytokine Production
Positive Regulation Of Cytokine Production
Inflammatory Response
Immune Response
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
JNK Cascade
Response To Mechanical Stimulus
Negative Regulation Of Integrin Activation
Response To Lipid
Response To Prostaglandin E
T-helper Cell Differentiation
Negative Regulation Of Inflammatory Response
Positive Regulation Of Inflammatory Response
Regulation Of Stress Fiber Assembly
Bone Development
ERK1 And ERK2 Cascade
Cellular Response To Mechanical Stimulus
Cellular Response To Prostaglandin E Stimulus
Negative Regulation Of Eosinophil Extravasation
Pathways
MHC class II antigen presentation
RHO GTPases activate KTN1
COPI-dependent Golgi-to-ER retrograde traffic
Signaling by ALK fusions and activated point mutants
Kinesins
Prostanoid ligand receptors
G alpha (s) signalling events
Drugs
Dinoprostone
Misoprostol
Trichostatin A
Limaprost
Castor oil
Grapiprant
Rivenprost
Rivenprost
Diseases
GWAS
Autism spectrum disorder or schizophrenia (
28540026
)
Bipolar disorder (
31043756
)
Body mass index (
25673413
28892062
)
Brain morphology (MOSTest) (
32665545
)
Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) (
31374203
)
Schizophrenia (
25056061
)
Smoking behaviour (cigarette pack-years) (
30679032
)
Urate levels (
31578528
)
Allergic disease (asthma, hay fever or eczema) (
29083406
)
Ankylosing spondylitis (
21743469
23749187
)
Aspartate aminotransferase levels (
33547301
)
Blood urea nitrogen levels (
31152163
)
Colorectal cancer or advanced adenoma (
30510241
)
Crohn's disease (
18587394
26278503
17684544
22936669
22412388
21102463
)
Gastric cancer (
22037551
26098866
)
Inflammatory bowel disease (
23128233
)
Multiple sclerosis (
22570697
21833088
28445677
19525953
)
Pediatric autoimmune diseases (
26301688
)
Red blood cell count (
32888494
)
Selective IgA deficiency (
27723758
)
Self-reported allergy (
23817569
)
Serum urea levels (
30808845
)
Type 1 diabetes (
34127860
)
Ulcerative colitis (
21297633
)
Interacting Genes
29 interacting genes:
ADRB2
AP1AR
APP
ATCAY
BNIP2
CLSTN1
ERBB2
F2RL1
HSPB1
KIF2A
KIF5C
KLC2
KRT31
LRSAM1
MAPK6
MAPK8IP1
MAPK8IP2
MAPK8IP3
NIN
ODAD1
ODF1
PCM1
PLEKHM2
PTGER4
SNCA
SPAG9
TACC3
TSC1
YWHAB
42 interacting genes:
ACTN4
ACY3
ANAPC7
ATXN10
BIN1
BNIP1
CDPF1
CFAP298
CRADD
CRY2
CTNND2
DPF1
DST
EHMT2
FEM1A
GJC2
HMOX1
HMOX2
HOPX
KLC1
NISCH
NUBP2
NUP153
PDLIM1
PMPCB
PPP1R3F
PRDX1
PSMC1
PTPRA
RNF220
RTF2
SLBP
SLC39A8
SND1
SPP1
ST13
SUGT1
TMEM161A
TRAP1
VSTM2A
WDR19
ZNF337
Entrez ID
3831
5734
HPRD ID
02489
03350
Ensembl ID
ENSG00000126214
ENSG00000171522
Uniprot IDs
F8W6L3
G3V2E7
G3V3H3
G3V5R9
G5E9S8
Q07866
Q7RTQ2
A0PJF5
P35408
PDB IDs
3NF1
5OJ8
7AI4
7AIE
5YHL
5YWY
7D7M
8GCM
8GCP
8GD9
8GDA
8GDB
Enriched GO Terms of Interacting Partners
?
Kinesin Binding
MAP-kinase Scaffold Activity
JUN Kinase Binding
Protein Localization To Synapse
Positive Regulation Of MAPK Cascade
Microtubule-based Process
Perinuclear Region Of Cytoplasm
Microtubule-based Movement
Protein Localization To Cell Junction
Anterograde Axonal Protein Transport
Protein Transport Along Microtubule
Organelle Localization
Regulation Of MAPK Cascade
MAPK Cascade
Regulation Of JNK Cascade
Cytoskeleton
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Cell Projection
Axonal Growth Cone
Axo-dendritic Transport
Transport Along Microtubule
Ciliary Basal Body
Lysosome
Cytoskeleton-dependent Intracellular Transport
Positive Regulation Of Intracellular Signal Transduction
Positive Regulation Of JNK Cascade
Microtubule-based Transport
Regulation Of Supramolecular Fiber Organization
Protein-containing Complex
Leukocyte Activation
Anterograde Axonal Transport
Protein Kinase Inhibitor Activity
Kinesin Complex
Axon
Modulation Of Excitatory Postsynaptic Potential
Receptor Localization To Synapse
Positive Regulation Of Signal Transduction
Centriolar Subdistal Appendage
Mitotic Spindle
Growth Cone
Negative Regulation Of G Protein-coupled Receptor Signaling Pathway
Cell Projection Organization
Intracellular Signaling Cassette
Lysosome Localization
Microtubule Anchoring At Centrosome
Regulation Of G Protein-coupled Receptor Signaling Pathway
Cytoplasm
Cell Activation
JNK Cascade
Heme Oxidation
Heme Oxygenase (decyclizing) Activity
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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