KLC1 and CLSTN1

Number of citations of the paper that reports this interaction (PMID 17332754)
37

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		KLC1	CLSTN1
Gene Name		kinesin light chain 1	calsyntenin 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Kinesin Complex Microtubule Membrane Cytoplasmic Membrane-bounded Vesicle Axon Growth Cone Ciliary Rootlet Neuronal Cell Body	Golgi Membrane Nucleus Endoplasmic Reticulum Membrane Integral Component Of Membrane Cell Junction Cell Projection Postsynaptic Membrane Extracellular Vesicular Exosome
	Molecular Function	Motor Activity Microtubule Motor Activity Protein Binding Tubulin Binding	Beta-amyloid Binding Calcium Ion Binding Protein Binding Kinesin Binding X11-like Protein Binding
	Biological Process	Intracellular Protein Transport Microtubule-based Movement Blood Coagulation Axon Cargo Transport Metabolic Process Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Protein Localization To Synapse Stress Granule Disassembly	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules
Pathways		MHC class II antigen presentation Kinesins Factors involved in megakaryocyte development and platelet production Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: APP BNIP2 CCDC114 CLSTN1 KIF2A KIF5C KLC2 KRT31 LRSAM1 MAPK6 MAPK8IP1 MAPK8IP2 MAPK8IP3 ODF1 PLEKHM2 SNCA SPAG9 YWHAB	14 interactors: APBA2 APBB1 BAHCC1 COL17A1 KIF2A KLC1 KLC2 MCM3AP MDM2 PRNP SETDB1 SLK TOPBP1 TRIP12
Entrez ID		3831	22883
HPRD ID		02489	10837
Ensembl ID		ENSG00000126214	ENSG00000171603
Uniprot IDs		F8W6L3 G3V2E7 G3V3H3 G3V5R9 Q07866 Q7RTQ2	B3KMD3 B4E3Q1 O94985
PDB IDs		3NF1
Enriched GO Terms of Interacting Partners?		MAPK Cascade Signal Transduction By Phosphorylation JNK Cascade Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Regulation Of Phosphorylation Regulation Of MAPK Cascade Regulation Of Phosphorus Metabolic Process Regulation Of JNK Cascade Regulation Of Protein Phosphorylation Regulation Of Stress-activated MAPK Cascade Positive Regulation Of MAPK Cascade Positive Regulation Of Protein Kinase Activity Positive Regulation Of Kinase Activity Positive Regulation Of Phosphorylation Phosphorylation Regulation Of JUN Kinase Activity Positive Regulation Of Transferase Activity Cell Morphogenesis Involved In Neuron Differentiation Microtubule-based Movement Positive Regulation Of Catalytic Activity Generation Of Neurons Neuron Projection Morphogenesis Positive Regulation Of Cellular Protein Metabolic Process Neurogenesis Nervous System Development Positive Regulation Of Stress-activated MAPK Cascade Cytoskeleton-dependent Intracellular Transport Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Cell Morphogenesis Involved In Differentiation Positive Regulation Of Protein Phosphorylation Regulation Of Catalytic Activity Axon Guidance Positive Regulation Of Protein Metabolic Process Microtubule-based Process Positive Regulation Of Signal Transduction Positive Regulation Of Intracellular Signal Transduction Neuron Projection Development Mating Behavior Cell Projection Morphogenesis Cell Differentiation Regulation Of Cellular Protein Metabolic Process Cell Part Morphogenesis Response To Stress Activation Of JUN Kinase Activity Positive Regulation Of Protein Modification Process Vesicle-mediated Transport Regulation Of Signal Transduction	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Regulation Of Response To DNA Damage Stimulus Response To Stress Antigen Processing And Presentation Of Peptide Antigen Axon Cargo Transport Peptidyl-lysine Modification Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Antigen Processing And Presentation Regulation Of DNA Repair Cellular Response To UV-C Cellular Response To Vitamin B1 Negative Regulation Of Thymidylate Synthase Biosynthetic Process Microtubule-based Movement Movement Of Cell Or Subcellular Component Cellular Response To DNA Damage Stimulus Stress Granule Disassembly Negative Regulation Of Protein Metabolic Process Blood Coagulation Negative Regulation Of Histone H2A K63-linked Ubiquitination Hemostasis Negative Regulation Of Cell Cycle Response To Radiation Regulation Of Histone Ubiquitination Negative Regulation Of Protein K63-linked Ubiquitination Traversing Start Control Point Of Mitotic Cell Cycle Negative Regulation Of Calcineurin-NFAT Signaling Cascade Cell Cycle Process Microtubule-based Transport DNA Metabolic Process Cytoskeleton-dependent Intracellular Transport Response To Vitamin B1 Response To Ether Cell Cycle Arrest Cellular Component Assembly Cellular Response To Copper Ion Regulation Of Protein K63-linked Ubiquitination Negative Regulation Of Double-strand Break Repair Negative Regulation Of Calcium-mediated Signaling Regulation Of Body Fluid Levels Behavior Protein Localization To Nucleus Negative Regulation Of DNA Repair DNA Repair Chromatin Modification Wound Healing Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Interleukin-17 Production Histone H3-K9 Trimethylation
Tagcloud ?		amyloidogenesis amyloidogenic arise axonal cargos causal collectively concepts controversial defects dysregulation impairs implicate implicates inevitably kinesin klc1ve modifier morihara neurodegeneration perpetuates reciprocal secretory splice splicing transport triggers unbiased vicious	adhesion adhesive atypical bead broad cadherin caenorhabditis calsyntenin calsyntenins characterizing cloned diffusible ectodomains elegans heterophilic homophilic idea mediate mediates members nervous preferences repeats sorting superfamily vertebrate zebrafish
Tagcloud (Difference) ?		amyloidogenesis amyloidogenic arise axonal cargos causal collectively concepts controversial defects dysregulation impairs implicate implicates inevitably kinesin klc1ve modifier morihara neurodegeneration perpetuates reciprocal secretory splice splicing transport triggers unbiased vicious	adhesion adhesive atypical bead broad cadherin caenorhabditis calsyntenin calsyntenins characterizing cloned diffusible ectodomains elegans heterophilic homophilic idea mediate mediates members nervous preferences repeats sorting superfamily vertebrate zebrafish
Tagcloud (Intersection) ?