KCNJ12 and LIN7B

Number of citations of the paper that reports this interaction (PMID 14960569)
32

Data Source:
HPRD (in vivo)

		KCNJ12	LIN7B
Gene Name		potassium channel, inwardly rectifying subfamily J, member 12	lin-7 homolog B (C. elegans)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Intrinsic Component Of Membrane	Cell-cell Junction Tight Junction Postsynaptic Density Basolateral Plasma Membrane Neuron Projection Synapse Postsynaptic Membrane MPP7-DLG1-LIN7 Complex
	Molecular Function	Inward Rectifier Potassium Channel Activity	Protein Domain Specific Binding L27 Domain Binding
	Biological Process	Potassium Ion Transport Muscle Contraction Synaptic Transmission Regulation Of Heart Contraction Potassium Ion Import Regulation Of Ion Transmembrane Transport Protein Homotetramerization	Exocytosis Neurotransmitter Secretion Asymmetric Protein Localization Protein Transport Maintenance Of Epithelial Cell Apical/basal Polarity Protein Localization To Basolateral Plasma Membrane
Pathways		GABA B receptor activation Inwardly rectifying K+ channels GABA receptor activation Activation of G protein gated Potassium channels Classical Kir channels Activation of GABAB receptors Potassium Channels Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits Transmission across Chemical Synapses
Drugs		Dofetilide
Diseases
GWAS		Height ( 20881960)
Protein-Protein Interactions		16 interactors: ABLIM1 APBA1 CASK DLG1 DLG2 DLG3 DLG4 DMD DTNA LIN7A LIN7B LIN7C PRKACA SNTA1 SNTB1 SNTB2	11 interactors: ABCA1 APBA1 ASIC3 BAIAP2 CASK DLG4 GNG13 GRIK2 GRIN2B KCNJ12 KCNJ4
Entrez ID		3768	64130
HPRD ID		09083	10040
Ensembl ID		ENSG00000184185	ENSG00000104863
Uniprot IDs		Q14500	Q9HAP6
PDB IDs			2DKR
Enriched GO Terms of Interacting Partners?		Establishment Or Maintenance Of Apical/basal Cell Polarity Cell-cell Signaling Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Maintenance Of Apical/basal Cell Polarity Receptor Localization To Synapse Synaptic Transmission Maintenance Of Cell Polarity Nucleotide Phosphorylation Protein Localization To Synapse Establishment Or Maintenance Of Cell Polarity Protein Localization To Membrane Protein Localization To Basolateral Plasma Membrane Maintenance Of Epithelial Cell Apical/basal Polarity Membrane Organization Cellular Protein Localization Receptor Clustering Regulation Of Ion Transmembrane Transport Muscle Contraction Muscle System Process Protein Localization Asymmetric Protein Localization Negative Regulation Of Peptidyl-cysteine S-nitrosylation Regulation Of Ion Transport Regulation Of Sodium Ion Transmembrane Transport Secretion Protein Localization To Plasma Membrane Cellular Localization Endomembrane System Organization Regulation Of Sodium Ion Transport Plasma Membrane Organization Secretion By Cell Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Movement Of Cell Or Subcellular Component Anatomical Structure Development Nucleotide Metabolic Process Regulation Of Membrane Potential Regulation Of Striated Muscle Contraction Chemotaxis Nervous System Development System Development Nucleobase-containing Small Molecule Metabolic Process Neurotransmitter Secretion Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Exocytosis Developmental Process Signaling Cellular Component Assembly Cell Communication Axon Guidance	Synaptic Transmission Ion Transport Regulation Of Synaptic Plasticity Cell-cell Signaling Transport Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Signaling Cell Communication Regulation Of Synaptic Transmission Ion Transmembrane Transport Membrane Depolarization Metal Ion Transport Regulation Of Ion Transmembrane Transport Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain Transmembrane Transport Potassium Ion Import Regulation Of Long-term Neuronal Synaptic Plasticity Neurological System Process Cation Transport Behavior Behavioral Fear Response Detection Of Mechanical Stimulus Involved In Sensory Perception Regulation Of Ion Transport Fear Response Secretion Synaptic Transmission, Glutamatergic Ionotropic Glutamate Receptor Signaling Pathway Detection Of Mechanical Stimulus Receptor Clustering Regulation Of Membrane Potential Regulation Of Neuronal Synaptic Plasticity Nucleotide Phosphorylation Glutamate Receptor Signaling Pathway Sensory Perception Of Taste Neuron-neuron Synaptic Transmission Membrane Organization Enterobactin Transport Cation Transmembrane Transport Multicellular Organismal Response To Stress Sensory Perception Of Pain Response To External Stimulus Organic Anion Transport Detection Of Chemical Stimulus Involved In Sensory Perception Of Pain Cellular Component Assembly Single-organism Behavior Positive Regulation Of Synaptic Transmission Establishment Of Localization In Cell Siderophore Transport Secretion By Cell
Tagcloud ?			10p12 255j24 adopter ak057360 ak078849 apicobasal av260217 bc038105 crb d10s588 drosoplila emp55 flj32798 gukc inadl lin7a lin7c mpdz mpp2 mpp3 mpp7 mupp1 pals2 patj rp24 scrib scribble sdt stardust
Tagcloud (Difference) ?			10p12 255j24 adopter ak057360 ak078849 apicobasal av260217 bc038105 crb d10s588 drosoplila emp55 flj32798 gukc inadl lin7a lin7c mpdz mpp2 mpp3 mpp7 mupp1 pals2 patj rp24 scrib scribble sdt stardust
Tagcloud (Intersection) ?