LIN7B and GNG13

Number of citations of the paper that reports this interaction (PMID 16473877)
8

Data Source:
HPRD (two hybrid)

		LIN7B	GNG13
Gene Name		lin-7 homolog B (C. elegans)	guanine nucleotide binding protein (G protein), gamma 13
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cell-cell Junction Tight Junction Postsynaptic Density Basolateral Plasma Membrane Neuron Projection Synapse Postsynaptic Membrane MPP7-DLG1-LIN7 Complex	Heterotrimeric G-protein Complex Plasma Membrane
	Molecular Function	Protein Domain Specific Binding L27 Domain Binding	Signal Transducer Activity G-protein Beta-subunit Binding
	Biological Process	Exocytosis Neurotransmitter Secretion Asymmetric Protein Localization Protein Transport Maintenance Of Epithelial Cell Apical/basal Polarity Protein Localization To Basolateral Plasma Membrane	Energy Reserve Metabolic Process Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Small Molecule Metabolic Process Sensory Perception Of Taste Cellular Response To Glucagon Stimulus
Pathways			Signaling by GPCR Glucagon-like Peptide-1 (GLP1) regulates insulin secretion ADP signalling through P2Y purinoceptor 1 Integration of energy metabolism G alpha (s) signalling events Glucagon-type ligand receptors G beta:gamma signalling through PLC beta Signaling by Wnt Metabolic disorders of biological oxidation enzymes Peptide hormone metabolism Gastrin-CREB signalling pathway via PKC and MAPK Thromboxane signalling through TP receptor G alpha (z) signalling events G alpha (i) signalling events Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Glucagon signaling in metabolic regulation ADP signalling through P2Y purinoceptor 12 G-protein beta:gamma signalling Opioid Signalling Activation of Kainate Receptors upon glutamate binding Aquaporin-mediated transport Adrenaline,noradrenaline inhibits insulin secretion G alpha (q) signalling events GPCR downstream signaling Platelet homeostasis Platelet activation, signaling and aggregation Transmission across Chemical Synapses G alpha (q) signalling events Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signal amplification G beta:gamma signalling through PI3Kgamma G alpha (12/13) signalling events Class B/2 (Secretin family receptors) Incretin synthesis, secretion, and inactivation Prostacyclin signalling through prostacyclin receptor Vasopressin regulates renal water homeostasis via Aquaporins Regulation of insulin secretion GPCR ligand binding beta-catenin independent WNT signaling Thrombin signalling through proteinase activated receptors (PARs) Presynaptic function of Kainate receptors Ca2+ pathway G-protein activation Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: ABCA1 APBA1 ASIC3 BAIAP2 CASK DLG4 GNG13 GRIK2 GRIN2B KCNJ12 KCNJ4	9 interactors: DLG1 DLG4 GNAT3 GNB1 GNB2 GNB3 GNB4 GNB5 LIN7B
Entrez ID		64130	51764
HPRD ID		10040	12116
Ensembl ID		ENSG00000104863	ENSG00000127588
Uniprot IDs		Q9HAP6	Q9P2W3
PDB IDs		2DKR
Enriched GO Terms of Interacting Partners?		Synaptic Transmission Ion Transport Regulation Of Synaptic Plasticity Cell-cell Signaling Transport Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Signaling Cell Communication Regulation Of Synaptic Transmission Ion Transmembrane Transport Membrane Depolarization Metal Ion Transport Regulation Of Ion Transmembrane Transport Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain Transmembrane Transport Potassium Ion Import Regulation Of Long-term Neuronal Synaptic Plasticity Neurological System Process Cation Transport Behavior Behavioral Fear Response Detection Of Mechanical Stimulus Involved In Sensory Perception Regulation Of Ion Transport Fear Response Secretion Synaptic Transmission, Glutamatergic Ionotropic Glutamate Receptor Signaling Pathway Detection Of Mechanical Stimulus Receptor Clustering Regulation Of Membrane Potential Regulation Of Neuronal Synaptic Plasticity Nucleotide Phosphorylation Glutamate Receptor Signaling Pathway Sensory Perception Of Taste Neuron-neuron Synaptic Transmission Membrane Organization Enterobactin Transport Cation Transmembrane Transport Multicellular Organismal Response To Stress Sensory Perception Of Pain Response To External Stimulus Organic Anion Transport Detection Of Chemical Stimulus Involved In Sensory Perception Of Pain Cellular Component Assembly Single-organism Behavior Positive Regulation Of Synaptic Transmission Establishment Of Localization In Cell Siderophore Transport Secretion By Cell	Cellular Response To Glucagon Stimulus Response To Glucagon Cell-cell Signaling Synaptic Transmission Establishment Or Maintenance Of Apical/basal Cell Polarity Energy Reserve Metabolic Process Maintenance Of Apical/basal Cell Polarity Signaling Receptor Localization To Synapse Energy Derivation By Oxidation Of Organic Compounds Cell Communication Cellular Response To Peptide Hormone Stimulus Detection Of Visible Light Cellular Response To Peptide Response To Organonitrogen Compound Detection Of Light Stimulus Maintenance Of Cell Polarity Generation Of Precursor Metabolites And Energy Response To Peptide Hormone Cellular Response To Organonitrogen Compound Protein Localization To Synapse Response To Peptide Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity G-protein Coupled Receptor Signaling Pathway Detection Of Abiotic Stimulus Establishment Or Maintenance Of Cell Polarity Regulation Of Rhodopsin Mediated Signaling Pathway Cortical Actin Cytoskeleton Organization Cellular Response To Hormone Stimulus Cortical Cytoskeleton Organization Rhodopsin Mediated Signaling Pathway Small Molecule Metabolic Process Receptor Clustering Nucleotide Phosphorylation Response To Light Stimulus Sensory Perception Of Taste Response To External Stimulus Response To Hormone Protein Localization To Membrane Phototransduction, Visible Light Regulation Of Ion Transmembrane Transport Response To Radiation Cellular Response To Light Stimulus Phototransduction Signal Transduction Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Detection Of Stimulus Response To Organic Substance Cellular Response To Radiation Response To Stimulus
Tagcloud ?		10p12 255j24 adopter ak057360 ak078849 apicobasal av260217 bc038105 crb d10s588 drosoplila emp55 flj32798 gukc inadl lin7a lin7c mpdz mpp2 mpp3 mpp7 mupp1 pals2 patj rp24 scrib scribble sdt stardust
Tagcloud (Difference) ?		10p12 255j24 adopter ak057360 ak078849 apicobasal av260217 bc038105 crb d10s588 drosoplila emp55 flj32798 gukc inadl lin7a lin7c mpdz mpp2 mpp3 mpp7 mupp1 pals2 patj rp24 scrib scribble sdt stardust
Tagcloud (Intersection) ?