LIN7B and GNG13

Number of citations of the paper that reports this interaction (PubMedID 16473877)
0

Data Source:
HPRD (two hybrid)

		LIN7B	GNG13
Description		lin-7 cell polarity scaffold B	G protein subunit gamma 13
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell-cell Junction Bicellular Tight Junction Membrane Basolateral Plasma Membrane Synapse Postsynaptic Membrane Anchoring Junction MPP7-DLG1-LIN7 Complex Presynapse Postsynaptic Density Membrane	Heterotrimeric G-protein Complex Plasma Membrane Membrane Dendrite Synapse
	Molecular Function	Protein Binding Protein Domain Specific Binding Protein-macromolecule Adaptor Activity	Protein Binding G-protein Beta-subunit Binding
	Biological Process	Exocytosis Neurotransmitter Secretion Regulation Of Synaptic Assembly At Neuromuscular Junction Protein Transport Synaptic Vesicle Transport	Signal Transduction G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Sensory Perception Of Taste
Pathways		Dopamine Neurotransmitter Release Cycle RHO GTPases Activate Rhotekin and Rhophilins Neurexins and neuroligins Assembly and cell surface presentation of NMDA receptors	Activation of G protein gated Potassium channels Glucagon signaling in metabolic regulation G-protein activation Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Olfactory Signaling Pathway Olfactory Signaling Pathway Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) ADP signalling through P2Y purinoceptor 12 G beta:gamma signalling through PI3Kgamma Prostacyclin signalling through prostacyclin receptor Prostacyclin signalling through prostacyclin receptor Adrenaline,noradrenaline inhibits insulin secretion Adrenaline,noradrenaline inhibits insulin secretion Ca2+ pathway Ca2+ pathway G alpha (q) signalling events G alpha (12/13) signalling events G beta:gamma signalling through PLC beta G alpha (s) signalling events ADP signalling through P2Y purinoceptor 1 ADP signalling through P2Y purinoceptor 1 G alpha (i) signalling events G alpha (z) signalling events Glucagon-type ligand receptors Thromboxane signalling through TP receptor Vasopressin regulates renal water homeostasis via Aquaporins Thrombin signalling through proteinase activated receptors (PARs) Thrombin signalling through proteinase activated receptors (PARs) Presynaptic function of Kainate receptors Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding G beta:gamma signalling through BTK G beta:gamma signalling through CDC42 Extra-nuclear estrogen signaling GPER1 signaling ADORA2B mediated anti-inflammatory cytokines production Sensory perception of sweet, bitter, and umami (glutamate) taste Sensory perception of sweet, bitter, and umami (glutamate) taste High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs
Diseases
GWAS			Mean corpuscular hemoglobin ( 32888494) Mean reticulocyte volume ( 32888494) Metabolite levels ( 23823483)
Interacting Genes		19 interacting genes: ABCA1 APBA1 ASIC3 BAIAP2 CASK DLG4 ENKD1 GNG13 GRIK2 GRIN2B KCNJ12 KCNJ4 MAK16 MPP7 NTAQ1 PSMB1 SNCA TCEANC TRAPPC12	39 interacting genes: ABI3 ADAMTSL4 BEX5 CCHCR1 CTAG1A CTAG1B CYSRT1 DISC1 DLG1 DLG4 EMILIN1 FTO GLRX3 GNAT3 GNB1 GNB2 GNB3 GNB4 GNB5 HAUS3 HOXA10 KRT27 KRT34 KRT37 KRT38 KRTAP9-2 LIN7B MEOX2 PAX5 PLSCR2 RASSF10 RPRM RSPO4 TEAD2 TEPSIN TRIM54 UQCC2 VPS16 WASHC3
Entrez ID		64130	51764
HPRD ID		10040	12116
Ensembl ID		ENSG00000104863	ENSG00000127588
Uniprot IDs		Q9HAP6	Q9P2W3
PDB IDs		2DKR
Enriched GO Terms of Interacting Partners?		Modulation Of Chemical Synaptic Transmission Regulation Of Neuronal Synaptic Plasticity Modulation Of Excitatory Postsynaptic Potential Regulation Of Synaptic Plasticity PDZ Domain Binding Regulation Of Long-term Neuronal Synaptic Plasticity Ionotropic Glutamate Receptor Signaling Pathway Positive Regulation Of Excitatory Postsynaptic Potential Regulation Of Membrane Potential Regulation Of Nervous System Process Ligand-gated Ion Channel Signaling Pathway Cellular Component Assembly Chemical Synaptic Transmission Positive Regulation Of Synaptic Transmission Glutamate Receptor Signaling Pathway Trans-synaptic Signaling Synaptic Signaling Protein-containing Complex Assembly Glutamate-gated Calcium Ion Channel Activity Excitatory Postsynaptic Potential Plasma Membrane Synapse Synaptic Membrane Scaffold Protein Binding Positive Regulation Of Protein-containing Complex Assembly Regulation Of Monoatomic Ion Transport Regulation Of Protein-containing Complex Assembly Protein-containing Complex Organization Protein Localization To Cell Junction Postsynaptic Membrane Ligand-gated Monoatomic Ion Channel Activity Involved In Regulation Of Presynaptic Membrane Potential Protein Tetramerization Postsynaptic Density Schaffer Collateral - CA1 Synapse Regulation Of Postsynaptic Membrane Potential Neuron Projection Terminus Postsynaptic Density Membrane Detection Of Temperature Stimulus Involved In Sensory Perception Detection Of Temperature Stimulus Regulation Of Monoatomic Ion Transmembrane Transport Inward Rectifier Potassium Channel Activity Regulation Of System Process Dendrite Cytoplasm Monoatomic Ion Transport Synaptic Vesicle Metal Ion Transport Regulation Of Presynaptic Membrane Potential Cell-cell Signaling Excitatory Synapse Ligand-gated Monoatomic Ion Channel Activity	Heterotrimeric G-protein Complex Signaling Receptor Complex Adaptor Activity Keratin Filament Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament MPP7-DLG1-LIN7 Complex Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Morphogenesis Of An Epithelium GTPase Binding Supramolecular Fiber Organization Protein-containing Complex Binding Presynapse Postsynaptic Density Cytoskeleton Organization Anatomical Structure Morphogenesis Tissue Morphogenesis Developmental Process Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane GTPase Activity Structural Molecule Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?