ITGAV and PLP1

Number of citations of the paper that reports this interaction (PMID 12196561)
21

Data Source:
HPRD (in vivo, in vitro)

		ITGAV	PLP1
Gene Name		integrin, alpha V	proteolipid protein 1
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Integrin Complex External Side Of Plasma Membrane Cell Surface Membrane Lamellipodium Membrane Filopodium Membrane Microvillus Membrane Ruffle Membrane Integrin Alphav-beta3 Complex Integrin Alphav-beta5 Complex Integrin Alphav-beta8 Complex Alphav-beta3 Integrin-IGF-1-IGF1R Complex Phagocytic Vesicle Extracellular Vesicular Exosome	Plasma Membrane Integral Component Of Membrane Myelin Sheath
	Molecular Function	Virus Receptor Activity Opsonin Binding Fibronectin Binding Protease Binding Protein Kinase C Binding Voltage-gated Calcium Channel Activity Protein Binding Insulin-like Growth Factor I Binding Metal Ion Binding Transforming Growth Factor Beta Binding Extracellular Matrix Binding Extracellular Matrix Protein Binding	Structural Molecule Activity Structural Constituent Of Myelin Sheath
	Biological Process	Angiogenesis Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Cell Adhesion Cell-matrix Adhesion Integrin-mediated Signaling Pathway Axon Guidance Blood Coagulation Positive Regulation Of Cell Proliferation Response To Virus Negative Regulation Of Macrophage Derived Foam Cell Differentiation Negative Regulation Of Lipid Storage Cell Growth Cell Migration Extracellular Matrix Organization Positive Regulation Of Cell Migration Cell-substrate Adhesion Negative Regulation Of Lipid Transport Positive Regulation Of Osteoblast Proliferation Heterotypic Cell-cell Adhesion Substrate Adhesion-dependent Cell Spreading Endodermal Cell Differentiation Apolipoprotein A-I-mediated Signaling Pathway Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Apoptotic Cell Clearance Negative Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Positive Regulation Of Cell Adhesion Viral Entry Into Host Cell Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Lipoprotein Metabolic Process Regulation Of Phagocytosis Leukocyte Migration Negative Chemotaxis Entry Of Symbiont Into Host Cell By Promotion Of Host Phagocytosis ERK1 And ERK2 Cascade Calcium Ion Transmembrane Transport Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Apoptotic Cell Clearance Negative Regulation Of Entry Of Bacterium Into Host Cell Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	Inflammatory Response Integrin-mediated Signaling Pathway Synaptic Transmission Axon Ensheathment Positive Regulation Of Gene Expression Astrocyte Development Substantia Nigra Development Central Nervous System Myelination Long-chain Fatty Acid Biosynthetic Process Cell Maturation Axon Development
Pathways		Signal transduction by L1 Axon guidance Elastic fibre formation L1CAM interactions Non-integrin membrane-ECM interactions VEGFA-VEGFR2 Pathway Cell surface interactions at the vascular wall PECAM1 interactions Molecules associated with elastic fibres Syndecan interactions Laminin interactions Signaling by VEGF ECM proteoglycans Integrin cell surface interactions Class I MHC mediated antigen processing & presentation Antigen processing-Cross presentation Cross-presentation of particulate exogenous antigens (phagosomes) Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		28 interactors: ADAM9 ANGPTL3 AUP1 AZGP1 CALR CD47 CYR61 EDIL3 F2R ICAM4 ITGB1 ITGB3 ITGB5 ITGB6 ITGB8 L1CAM MMP14 MMP2 NID1 NOV P2RY2 PAK4 PDGFRA PLP1 PTK2 SPP1 TGFB1 THY1	7 interactors: CALR CANX CLN8 ITGAV MAG MBP PTPRN
Entrez ID		3685	5354
HPRD ID		01903	02321
Ensembl ID		ENSG00000138448	ENSG00000123560
Uniprot IDs		B7ZLX0 P06756	A8K9L3 B4DI30 P60201
PDB IDs		1JV2 1L5G 1M1X 1U8C 3IJE 4G1E 4G1M	2XPG
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Organization Extracellular Structure Organization Cell Adhesion Integrin-mediated Signaling Pathway Regulation Of Cell Migration Positive Regulation Of Cell Migration Regulation Of Cell Adhesion Positive Regulation Of Cell Motility Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Cell-matrix Adhesion Regulation Of Locomotion Regulation Of Cellular Component Movement Cell-substrate Adhesion Positive Regulation Of Cell Adhesion Locomotion Regulation Of Cell-substrate Adhesion Cardiovascular System Development Blood Vessel Development Response To External Stimulus Vasculature Development Single Organismal Cell-cell Adhesion Multicellular Organismal Development Cell Surface Receptor Signaling Pathway Developmental Process Blood Vessel Morphogenesis Cell Migration Tissue Development Cell Motility Angiogenesis Movement Of Cell Or Subcellular Component Positive Regulation Of Cell-substrate Adhesion Anatomical Structure Development Signaling Cell Communication Response To Stimulus Positive Regulation Of Cell Proliferation Signal Transduction Chemotaxis Wound Healing Organ Development Blood Coagulation Hemostasis System Development Cell-cell Adhesion Mediated By Integrin Single Organism Reproductive Process Response To Wounding Positive Regulation Of Kinase Activity Anatomical Structure Morphogenesis	Aging Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Negative Regulation Of Neuron Differentiation Generation Of Neurons Negative Regulation Of Cell Differentiation Antigen Processing And Presentation Of Peptide Antigen Neurogenesis Substantia Nigra Development Response To Stress Antigen Processing And Presentation Negative Regulation Of Neurogenesis Positive Regulation Of Phagocytosis Negative Regulation Of Cell Development Neural Nucleus Development Immune System Process Chaperone-mediated Protein Folding Negative Regulation Of Axonogenesis Nervous System Development Regulation Of Phagocytosis Regulation Of Cell Morphogenesis Response To Steroid Hormone Midbrain Development Peptide Antigen Assembly With MHC Class I Protein Complex Negative Regulation Of Entry Of Bacterium Into Host Cell Entry Of Symbiont Into Host Cell By Promotion Of Host Phagocytosis Negative Regulation Of Cell Morphogenesis Involved In Differentiation Protein N-linked Glycosylation Via Asparagine Regulation Of Neuron Differentiation Positive Regulation Of Endocytosis Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Negative Regulation Of Neuron Projection Development Protein N-linked Glycosylation Protein Secretion Regulation Of Cell Differentiation Regulation Of Entry Of Bacterium Into Host Cell Dense Core Granule Maturation L-glutamate Uptake Involved In Synaptic Transmission Endocytosis Negative Regulation Of Cell Projection Organization Regulation Of Neurogenesis Defense Response To Nematode Negative Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Developmental Process Regulation Of Axonogenesis Cell Differentiation Signaling Cell Communication Sequestering Of Calcium Ion Regulation Of Cellular Component Organization
Tagcloud ?		bcl colorectal corresponding crc dissemination event extracellular ihc immunohistochemistry invasion ki matrix metastasis neoplastic overexpression perineural polymerase progression quantitative real regard resection sparc spread thbs1 underwent validation vcam vegf	bace1 bingo cdk2 clustering criterion cytoscape degs downloaded elavl1 glioma gse31262 hierarchical kif23 kobas language limma log2fc mbp multtest myelination omnibus ontology package pheatmap plug software string webgestalt wee1
Tagcloud (Difference) ?		bcl colorectal corresponding crc dissemination event extracellular ihc immunohistochemistry invasion ki matrix metastasis neoplastic overexpression perineural polymerase progression quantitative real regard resection sparc spread thbs1 underwent validation vcam vegf	bace1 bingo cdk2 clustering criterion cytoscape degs downloaded elavl1 glioma gse31262 hierarchical kif23 kobas language limma log2fc mbp multtest myelination omnibus ontology package pheatmap plug software string webgestalt wee1
Tagcloud (Intersection) ?