IRF3 and IKBKE

  • Number of citations of the paper that reports this interaction (PMID 12692549)
  • 461
  • Data Source:
  • BioGRID (enzymatic study)
  • HPRD (in vivo, in vitro)

IRF3

IKBKE

Gene Name interferon regulatory factor 3 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 25 interactors: CREBBP EP300 EWSR1 GRIP1 HSP90AA1 IKBKE IRF5 IRF7 MAPK8 MAVS PEX19 PIAS4 PPIB PRDX1 RB1 RBL1 RELA SERPINB2 SGTA SMURF2 SYT1 TBK1 TICAM1 TICAM2 TOMM70A 21 interactors: AZI2 BIRC2 BIRC3 CDC37 CHUK FKBP5 HSP90AA1 HSP90AB1 IRF3 IRF5 KTN1 MBP NFKBIA RELA SIKE1 TANK TBK1 TICAM1 TRAF2 TRIM27 XIAP
Entrez ID 3661 9641
HPRD ID 04769 05442
Ensembl ID ENSG00000126456 ENSG00000143466
Uniprot IDs E2GIM5 E2GIM6 E2GIM7 E2GIM8 E2GIM9 M0QYT9 Q14653 Q14164
PDB IDs 1J2F 1QWT 1T2K 1ZOQ 2O61 2O6G 2PI0 3A77 3QU6
Enriched GO Terms of Interacting Partners?
Tagcloud ?
antiviral  called  cif  coactivator  composed  contain  creb  cytomegalovirus  defense  establishes  foreskin  hcmv  immediate  interacts  interferon  interferons  intrinsic  isg54  latent  numerous  participate  possess  responsive  shortcut  stat  stat1  stat2  stimulated  tentatively 
accelerate  adherent  bc  canonical  consequently  cooperated  cooperation  efficiently  eventually  her2  ikkepsilon  incurable  ink4a  kill  kinome  knock  lapatinib  lenti  neoadjuvant  nfkb  potentiate  senescence  shrna  succumb  suppress  tbk1  tumorspheres  urgent  xenograft 
Tagcloud (Difference) ?
antiviral  called  cif  coactivator  composed  contain  creb  cytomegalovirus  defense  establishes  foreskin  hcmv  immediate  interacts  interferon  interferons  intrinsic  isg54  latent  numerous  participate  possess  responsive  shortcut  stat  stat1  stat2  stimulated  tentatively 
accelerate  adherent  bc  canonical  consequently  cooperated  cooperation  efficiently  eventually  her2  ikkepsilon  incurable  ink4a  kill  kinome  knock  lapatinib  lenti  neoadjuvant  nfkb  potentiate  senescence  shrna  succumb  suppress  tbk1  tumorspheres  urgent  xenograft 
Tagcloud (Intersection) ?