IRF3 and MAVS

  • Number of citations of the paper that reports this interaction (PMID 16153868)
  • 390
  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology, affinity chromatography technology)
  • HPRD (in vivo, in vitro)

IRF3

MAVS

Gene Name interferon regulatory factor 3 mitochondrial antiviral signaling protein
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 25 interactors: CREBBP EP300 EWSR1 GRIP1 HSP90AA1 IKBKE IRF5 IRF7 MAPK8 MAVS PEX19 PIAS4 PPIB PRDX1 RB1 RBL1 RELA SERPINB2 SGTA SMURF2 SYT1 TBK1 TICAM1 TICAM2 TOMM70A 19 interactors: ABL1 BAG6 CALCOCO2 DDX58 IRF3 IRF5 IRF7 KCNIP3 MAP3K7 OAS3 RIPK2 RNF5 SMURF2 STAT1 TBK1 TICAM1 TRAF5 TRAF6 UBE4A
Entrez ID 3661 57506
HPRD ID 04769 13847
Ensembl ID ENSG00000126456
Uniprot IDs E2GIM5 E2GIM6 E2GIM7 E2GIM8 E2GIM9 M0QYT9 Q14653 M1P2Z0 Q7Z434
PDB IDs 1J2F 1QWT 1T2K 1ZOQ 2O61 2O6G 2PI0 3A77 3QU6 2VGQ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
antiviral  called  cif  coactivator  composed  contain  creb  cytomegalovirus  defense  establishes  foreskin  hcmv  immediate  interacts  interferon  interferons  intrinsic  isg54  latent  numerous  participate  possess  responsive  shortcut  stat  stat1  stat2  stimulated  tentatively 
2b  2c  3c  3cpro  adaptors  asp  classic  cleavage  comprises  conducts  cys  evasion  genera  glu  innate  irf3  irf7  livestock  nemo  p1  p2  picornavirus  polyproteins  preference  triad  trif  vp1  vp2  vp3 
Tagcloud (Difference) ?
antiviral  called  cif  coactivator  composed  contain  creb  cytomegalovirus  defense  establishes  foreskin  hcmv  immediate  interacts  interferon  interferons  intrinsic  isg54  latent  numerous  participate  possess  responsive  shortcut  stat  stat1  stat2  stimulated  tentatively 
2b  2c  3c  3cpro  adaptors  asp  classic  cleavage  comprises  conducts  cys  evasion  genera  glu  innate  irf7  livestock  nemo  p1  p2  picornavirus  polyproteins  preference  triad  trif  vp1  vp2  vp3 
Tagcloud (Intersection) ?
irf3