PPBP and CCL28

Number of citations of the paper that reports this interaction (PubMedID 28381538)
0

Data Source:
BioGRID (pull down)

		PPBP	CCL28
Description		pro-platelet basic protein	C-C motif chemokine ligand 28
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Platelet Alpha Granule Platelet Alpha Granule Lumen Tertiary Granule Lumen	Extracellular Region Extracellular Space Secretory Granule Extracellular Exosome
	Molecular Function	Cytokine Activity Protein Binding Chemokine Activity Growth Factor Activity CXCR Chemokine Receptor Binding D-glucose Transmembrane Transporter Activity	Cytokine Activity Protein Binding Chemokine Activity Chemokine Receptor Binding CXCR Chemokine Receptor Binding
	Biological Process	Chemotaxis Defense Response Inflammatory Response Immune Response Signal Transduction Neutrophil Chemotaxis Killing Of Cells Of Another Organism Defense Response To Bacterium Positive Regulation Of Cell Division Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cellular Response To Lipopolysaccharide D-glucose Transmembrane Transport	Positive Regulation Of Cell-matrix Adhesion Chemotaxis Inflammatory Response Immune Response Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Nutrient Neutrophil Chemotaxis Killing Of Cells Of Another Organism Cytolysis In Another Organism Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cellular Response To Lipopolysaccharide Negative Regulation Of Leukocyte Tethering Or Rolling
Pathways		Platelet degranulation Chemokine receptors bind chemokines G alpha (i) signalling events Neutrophil degranulation	Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs		Ethanesulfonic acid Copper
Diseases
GWAS		Metabolite levels ( 22916037)	Metabolite levels (X-11787) ( 23934736) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
Interacting Genes		32 interacting genes: CCL13 CCL21 CCL26 CCL28 CCL5 CCL8 CELF1 CMTM6 COPG1 COPS7A COX17 CTSG CXCL10 CXCL11 CXCL12 CXCL14 CXCL6 CXCL9 CXCR1 CXCR2 DMWD EFNA1 MAPK6 MOB3B NDUFB11 NR4A1 PLEKHJ1 PMAIP1 RAB10 RPS27 SCFD1 STRN4	26 interacting genes: ACKR2 CCL11 CCL13 CCL17 CCL21 CCL26 CCL5 CCR10 CCR3 CXCL10 CXCL12 CXCL13 CXCL14 CXCL17 CXCL2 CXCL9 DDI1 DYNLT3 PF4 PF4V1 PPBP PSMA3 STUB1 TSC1 XCL1 XCL2
Entrez ID		5473	56477
HPRD ID		07171	05577
Ensembl ID		ENSG00000163736	ENSG00000151882
Uniprot IDs		P02775	A0N0Q3 D6RC73 Q9NRJ3
PDB IDs		1F9P 1NAP 1TVX	6CWS
Enriched GO Terms of Interacting Partners?		Chemokine Activity Cell Chemotaxis Leukocyte Chemotaxis Chemokine-mediated Signaling Pathway Chemotaxis Locomotion Antimicrobial Humoral Response Granulocyte Chemotaxis Leukocyte Migration Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Myeloid Leukocyte Migration Granulocyte Migration Humoral Immune Response Cytokine Activity Killing Of Cells Of Another Organism Cell Migration Cytokine-mediated Signaling Pathway Mononuclear Cell Migration Cell Motility Cell Killing CXCR Chemokine Receptor Binding Inflammatory Response Eosinophil Chemotaxis Defense Response To Symbiont Eosinophil Migration Defense Response Defense Response To Other Organism Immune System Process Neutrophil Chemotaxis Immune Response CCR Chemokine Receptor Binding Chemokine Receptor Binding Neutrophil Migration Response To External Biotic Stimulus Response To Other Organism Cell-cell Signaling G Protein-coupled Receptor Signaling Pathway Signaling Cell Communication T Cell Chemotaxis Dendritic Cell Chemotaxis Negative Regulation Of Leukocyte Tethering Or Rolling CXCR3 Chemokine Receptor Binding Dendritic Cell Migration Lymphocyte Chemotaxis Neutrophil Activation Negative Regulation Of Cellular Extravasation T Cell Migration Positive Regulation Of T Cell Migration Extracellular Space	Chemokine Activity Cell Chemotaxis Chemotaxis Locomotion Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Antimicrobial Humoral Response Chemokine-mediated Signaling Pathway Cytokine Activity Humoral Immune Response Leukocyte Chemotaxis Cell Migration Granulocyte Chemotaxis Killing Of Cells Of Another Organism Cell Motility Myeloid Leukocyte Migration Granulocyte Migration Immune Response Leukocyte Migration Inflammatory Response Cell Killing Cytokine-mediated Signaling Pathway Immune System Process Defense Response To Symbiont CXCR Chemokine Receptor Binding Defense Response To Other Organism Defense Response CCR Chemokine Receptor Binding Response To Other Organism G Protein-coupled Receptor Signaling Pathway Mononuclear Cell Migration Extracellular Space Response To External Biotic Stimulus Neutrophil Chemotaxis Neutrophil Migration Response To Stress Positive Regulation Of T Cell Migration Regulation Of T Cell Chemotaxis Extracellular Region CXCR3 Chemokine Receptor Binding Positive Regulation Of Chemotaxis Positive Regulation Of Lymphocyte Migration Positive Regulation Of Leukocyte Chemotaxis Eosinophil Chemotaxis Positive Regulation Of Mononuclear Cell Migration Regulation Of T Cell Migration Eosinophil Migration Positive Regulation Of Cell Migration Regulation Of Lymphocyte Chemotaxis Lymphocyte Chemotaxis Signal Transduction
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