APOE and PRNP

  • Number of citations of the paper that reports this interaction (PMID 15146195)
  • 32
  • Data Source:
  • HPRD (in vivo)

APOE

PRNP

Gene Name apolipoprotein E prion protein
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 54 interactors: A2M ACTG1 ALB ANKH APP ARFGAP1 C19orf52 CDC37 CNTF CSNK2A1 CTSB CYP2C18 CYP2C8 ECSIT ELAVL1 EPN2 FARSA FBXL12 FOXG1 FXYD7 GCDH HTRA1 IFIT3 IFIT5 IQSEC1 LCAT LDLR LONP1 LOXL4 LRP1 LRP2 LRP8 MAP2 MAPT MAST1 MID1IP1 NEFM NOS3 PCMT1 PDCD4 PLEKHA6 PLTP PRAM1 PRDX2 PRNP PSEN1 RHEB RNF32 RPL4 SCARB1 ST13 TYRO3 VLDLR ZNF558 76 interactors: ABT1 ADAM23 ADAP2 AGO1 AIFM3 APBB1 APLP1 APLP2 APOE ARHGAP15 BAG6 BAZ2B C7orf50 CAV1 CCDC149 CIRBP CIRH1A CLSTN1 CLU CNP CNTN1 CSN3 CSNK2A1 CSNK2A2 CSNK2B CWC15 DDX47 DNM1 DPP6 DYRK3 ERI3 FAM27E3 FGF13 FHL1 GRB2 HSPA5 HSPD1 IER3 KIAA1191 L1CAM LSAMP MAG MARK4 MOG MTG1 NCAM1 NCAM2 NHP2 NOB1 OPCML P4HB PDE4DIP PLG PPFIBP2 PPP1R14A PSMA3 PTRH1 PVRL1 RBM22 RNPC3 RPL41 SCNM1 SPARCL1 STIP1 SURF2 TBPL1 TMEM237 TSC22D4 TSLP TYMSOS WDR5 WIBG ZFYVE28 ZKSCAN8 ZNF408 ZNF740
Entrez ID 348 5621
HPRD ID 00135 01453
Ensembl ID ENSG00000130203 ENSG00000171867
Uniprot IDs P02649 B2NI04 F7VJQ1 P04156 Q53YK7
PDB IDs 1B68 1BZ4 1EA8 1GS9 1H7I 1LE2 1LE4 1LPE 1NFN 1NFO 1OEF 1OEG 1OR2 1OR3 2KC3 2KNY 2L7B 1E1G 1E1J 1E1P 1E1S 1E1U 1E1W 1FKC 1FO7 1H0L 1HJM 1HJN 1I4M 1OEH 1OEI 1QLX 1QLZ 1QM0 1QM1 1QM2 1QM3 2IV4 2IV5 2IV6 2K1D 2KUN 2LBG 2LEJ 2LFT 2LSB 2LV1 2M8T 2OL9 2W9E 3HAF 3HAK 3HEQ 3HER 3HES 3HJ5 3HJX 3MD4 3MD5 3NHC 3NHD 3NVF 4DGI 4E1H 4E1I
Enriched GO Terms of Interacting Partners?
Tagcloud ?
aa  adenovirus  agreement  amyloid  amyloids  apoe3  apoe4  apoj  apolipoprotein  apolipoproteins  appear  cerebral  characterize  deficient  define  deposition  deposits  fibril  fibrillogenesis  fibrils  fragment  greatest  heterozygous  injected  lacking  lipoproteins  promoting  restored  utilized 
chelation  cooperatively  copper  cysteines  excitotoxicity  exert  favor  glun1  glun2a  glutamatergic  hippocampi  indeed  innovation  insults  interdependent  modulates  mounting  neurodegeneration  neuroprotection  nitric  nitrosylation  nmdar  organotypic  oxide  prion  prnp0  prpc  synapses  thiols 
Tagcloud (Difference) ?
aa  adenovirus  agreement  amyloid  amyloids  apoe3  apoe4  apoj  apolipoprotein  apolipoproteins  appear  cerebral  characterize  deficient  define  deposition  deposits  fibril  fibrillogenesis  fibrils  fragment  greatest  heterozygous  injected  lacking  lipoproteins  promoting  restored  utilized 
chelation  cooperatively  copper  cysteines  excitotoxicity  exert  favor  glun1  glun2a  glutamatergic  hippocampi  indeed  innovation  insults  interdependent  modulates  mounting  neurodegeneration  neuroprotection  nitric  nitrosylation  nmdar  organotypic  oxide  prion  prnp0  prpc  synapses  thiols 
Tagcloud (Intersection) ?