ACOT7 and UBQLN1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ACOT7	UBQLN1
Gene Name		acyl-CoA thioesterase 7	ubiquilin 1
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Cytosol Neuron Projection Cell Body Extracellular Vesicular Exosome	Proteasome Complex Nucleoplasm Cytoplasm Endoplasmic Reticulum Protein Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Fatty-acyl-CoA Binding Protein Binding Palmitoyl-CoA Hydrolase Activity Long-chain Fatty Acyl-CoA Binding Protein Homodimerization Activity Carboxylic Ester Hydrolase Activity	Protein Binding Kinase Binding Protein Domain Specific Binding
	Biological Process	Fatty Acid Catabolic Process Coenzyme A Biosynthetic Process Medium-chain Fatty-acyl-CoA Catabolic Process Long-chain Fatty-acyl-CoA Catabolic Process Medium-chain Fatty Acid Biosynthetic Process Palmitic Acid Biosynthetic Process	Regulation Of Protein Ubiquitination Response To Endoplasmic Reticulum Stress Cellular Response To Hypoxia Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS		QT interval ( 19305408)
Protein-Protein Interactions		10 interactors: ATXN1 ATXN1L CAMK2B CRYAB MAGEA6 POT1 TERF1 THAP1 TINF2 UBQLN1	151 interactors: ABCC2 ACOT7 ADRM1 AGPAT5 AGR2 AGR3 APP ASCL1 ATXN3 BPIFA1 C1QA C1QTNF2 CALU CARKD CCL7 CCNB1 CD47 CD99 CD99L2 CHGB CHRNA3 CHRNA4 CHRNB4 COL10A1 COL1A2 COLGALT2 COMTD1 CSTF2 CSTF2T CTAG1B CTAG2 CYB5R1 DEFA6 DNAJB2 EFEMP2 EP300 EPS15 ERP27 ETNK1 F8 FAM127A FAM127B FAM127C FAM189A2 FAM86B3P FAS FBXO25 FCGR2A FGF7 FKBP2 FN1 FZD7 GABRA1 GABRA2 GABRA3 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GHRL GIT2 GKAP1 GPX3 GRM2 GYPB HERC3 HES1 HGS HK2 HSD17B12 HSPA13 IGL IGLC1 IGLV2-14 IL6ST IST1 ITPRIPL1 KLHL42 LITAF MANBAL MCM7 MIEF1 MIEF2 MLLT6 MTOR NBL1 NDE1 NGLY1 NME3 NPPA NPY NUPL1 P4HB PBXIP1 PIK3IP1 PLA2G16 PNMA1 PPIB PPIC PRAP1 PRB1 PRPF40A PSEN1 PSEN2 PSMD4 PSMD6 PTN RARA RASSF5 RIC8A RNF208 RPN1 RSRC2 SCG5 SCMH1 SERPINE1 SERPINI2 SIL1 SLC29A2 SMAD9 SMIM2 SMR3B SPARC SRGN STMN3 TARDBP TFF1 TICAM1 TMCO6 TMEM31 TMEM37 TMUB2 TNFRSF1A TNFRSF1B TREX1 TRIM32 TXNDC12 UBB UBC UBE2V1 UBQLN4 UBXN1 UBXN4 VCP XPO4 ZFAND2B ZG16 ZG16B ZMYM4 ZNF343
Entrez ID		11332	29979
HPRD ID		12517	05440
Ensembl ID		ENSG00000097021	ENSG00000135018
Uniprot IDs		F5GWE2 O00154	Q9UMX0
PDB IDs		2QQ2	2JY5 2JY6 2KLC
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Replication Telomere Maintenance Telomere Assembly Negative Regulation Of Chromosome Organization Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of DNA Metabolic Process Positive Regulation Of Telomere Maintenance Positive Regulation Of Organelle Organization Regulation Of Telomerase Activity Regulation Of DNA Replication RNA-dependent DNA Replication Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Chromosome Organization Negative Regulation Of Biosynthetic Process Regulation Of DNA Biosynthetic Process Lung Alveolus Development Regulation Of Organelle Organization Negative Regulation Of Protein ADP-ribosylation Positive Regulation Of DNA Strand Elongation Inhibitory G-protein Coupled Receptor Phosphorylation Regulation Of Cellular Component Organization Response To Abiotic Stimulus Regulation Of Protein ADP-ribosylation Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Activation Of Meiosis Involved In Egg Activation Telomeric Loop Formation Age-dependent Telomere Shortening Positive Regulation Of Hematopoietic Stem Cell Proliferation Telomere Formation Via Telomerase Positive Regulation Of Cell Division Telomere Maintenance Via Telomere Shortening Negative Regulation Of Protein Glycosylation Activation Of Meiosis Positive Regulation Of DNA Metabolic Process Regulation Of Apoptotic Process Regulation Of Metabolic Process Telomere Capping Protein Localization To Chromosome, Telomeric Region Positive Regulation Of Helicase Activity Regulation Of Cell Death Positive Regulation Of Telomerase Activity Regulation Of Hematopoietic Stem Cell Proliferation Positive Regulation Of Telomere Maintenance Via Telomerase	Response To Stress Response To Organic Substance Positive Regulation Of Proteolysis Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Proteolysis Positive Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Extracellular Matrix Organization Extracellular Structure Organization Response To Stimulus Regulation Of Protein Metabolic Process Cellular Response To Histamine Cellular Response To Organic Substance Cell-cell Signaling Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Synaptic Transmission Platelet Degranulation Signal Transduction Regulation Of Protein Ubiquitination Regulation Of Protein Catabolic Process Regulation Of ERBB Signaling Pathway Response To Histamine Chloride Transmembrane Transport Response To Organic Cyclic Compound Positive Regulation Of Protein Catabolic Process Signaling Cell Surface Receptor Signaling Pathway Response To Abiotic Stimulus Gamma-aminobutyric Acid Signaling Pathway Response To Hypoxia Cell Communication Chloride Transport Notch Signaling Pathway Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Immune System Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Protein Modification Process Positive Regulation Of Cellular Metabolic Process Cellular Response To Stimulus Cellular Response To Oxygen Levels Regulation Of Cellular Process Defense Response Positive Regulation Of Cell Cycle Cellular Response To Ammonium Ion Notch Receptor Processing Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Tagcloud ?		16p11 17q21 2p21 autism auts2 cask categorised cnvs crebbp ctnnd2 delineating exonic grm8 homozygous incidental instrumental iq kb med13l microdeletion morbid ndds neurodevelopmental nrxn3 omim pafah1b1 satb2 sizing undiagnosed	affecting aid biomarkers biosynthesis contamination differentially elucidated evaluating exert exposed hepatic hepatotoxicity hnrnpc huwe1 itraq labeling ontology paf1 perfluorinated perfluorooctane pfos proteomic splicing sulfonate technology toxic transduction trigger whose
Tagcloud (Difference) ?		16p11 17q21 2p21 autism auts2 cask categorised cnvs crebbp ctnnd2 delineating exonic grm8 homozygous incidental instrumental iq kb med13l microdeletion morbid ndds neurodevelopmental nrxn3 omim pafah1b1 satb2 sizing undiagnosed	affecting aid biomarkers biosynthesis contamination differentially elucidated evaluating exert exposed hepatic hepatotoxicity hnrnpc huwe1 itraq labeling ontology paf1 perfluorinated perfluorooctane pfos proteomic splicing sulfonate technology toxic transduction trigger whose
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