ACOT7 and ENKD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ACOT7	ENKD1
Description		acyl-CoA thioesterase 7	enkurin domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Cytosol Extracellular Exosome	Spindle Pole Cytoplasm Centrosome Centriole Spindle Cytoskeleton Microtubule Cytoplasmic Microtubule Plasma Membrane Cilium Microtubule Cytoskeleton Ciliary Basal Body Cell Projection Ciliary Base 9+0 Non-motile Cilium
	Molecular Function	Fatty-acyl-CoA Binding Protein Binding Hydrolase Activity Thiolester Hydrolase Activity Long-chain Fatty Acyl-CoA Binding Protein Homodimerization Activity Fatty Acyl-CoA Hydrolase Activity Carboxylic Ester Hydrolase Activity Long-chain Fatty Acyl-CoA Hydrolase Activity	Protein Binding Microtubule Binding Alpha-tubulin Binding
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Acyl-CoA Metabolic Process Fatty Acid Catabolic Process Coenzyme A Biosynthetic Process Medium-chain Fatty-acyl-CoA Catabolic Process Long-chain Fatty-acyl-CoA Catabolic Process Medium-chain Fatty Acid Biosynthetic Process Palmitic Acid Biosynthetic Process	Establishment Of Mitotic Spindle Orientation Cell Projection Organization Motile Cilium Assembly Non-motile Cilium Assembly
Pathways		Mitochondrial Fatty Acid Beta-Oxidation
Drugs
Diseases
GWAS		A body shape index ( 34021172) Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) HDL cholesterol levels in HIV infection ( 33109212) Metabolite levels ( 31628463) QT interval ( 19305408) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172)	Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		26 interacting genes: ACOT12 ATXN1 ATXN1L BAG4 CAMK2B CDC42 CRYAB DAZAP2 DLC1 ENKD1 FXR1 HOXA1 LMNA MAGEA3 MAGEA6 NCOA5 POT1 POU6F1 SPATC1L TERF1 THAP1 TINF2 UBQLN1 UBQLN2 UBXN1 ZNF438	208 interacting genes: ABI1 ABI2 ACOT7 ACTMAP AKAP8L ANKRD23 ANKRD49 APP ARMC5 ASB3 AVPI1 BANP BCAS2 BCAS4 BCAT1 BEGAIN BEX3 BLZF1 BRAT1 C18orf54 C1orf105 CALCOCO1 CALCOCO2 CBY1 CBY2 CCDC102B CCDC13 CCDC136 CCDC28B CCDC85B CDCA4 CDPF1 CDR2 CDSN CEP55 CEP70 CHCHD3 CHRDL2 COA7 CTBP2 CYSRT1 DGCR6 DVL2 DVL3 DYDC1 ECM1 EEIG1 EFHC2 EIF4G1 EYA2 EZHIP FAM228A FAM90A1 FCHSD2 FKBP6 FOS FOSB FSD2 GADD45G GADD45GIP1 GET4 GFAP GIGYF1 GOLGA2 GOLGA6A GOLGA6L9 GPRASP3 GRHL3 GRIPAP1 HMBOX1 HNRNPH1 HOMEZ HOOK2 HOXA1 HSF2BP HSPB2 HSPB2-C11orf52 ID2 IGF1 IGFBP6 IKBKG IKZF3 JAKMIP1 KIFC3 KLHL20 KLHL26 KRT14 KRT15 KRT31 KRT35 KRT40 KRTAP10-5 KRTAP10-8 KRTAP11-1 KRTAP12-1 KRTAP13-2 KRTAP19-1 KRTAP19-5 KRTAP19-6 KRTAP4-11 KRTAP5-9 KRTAP6-2 LDOC1 LHX3 LIN7B LMO2 LRRC61 LZTS1 MAPK9 MATN4 MDFI MEIS3 MESD METTL27 MID2 MIF4GD MIPOL1 MISP MKRN3 MLH1 MORN3 MORN5 MRNIP MRPL28 MRPL38 MTUS2 MYF5 MYOZ3 N4BP3 NAB2 NBPF22P NBPF6 NCKIPSD NDUFB7 NEFL NFKBIA NHLRC4 NUTM1 OOEP PAK5 PDLIM7 PDZD4 PHC2 PIBF1 PICK1 PIK3R3 PKNOX2 PLSCR1 PNMA1 PNMA2 POLR3C PPP1CC PPP2R3C PRDM14 PRDM6 RAD54B RBCK1 RBM11 RBPMS RCN1 RUBCN RUNDC3A SLC15A2 SNRNP48 SORBS3 SPAG5 SPDEF SPSB3 SRGAP3 SSC4D STAC3 STXBP4 TENT5B TFIP11 TNNI1 TNS2 TOX2 TRAF1 TRAF2 TRAK1 TRGV7 TRIM23 TRIM27 TRIM35 TRIM54 TSC1 TSC22D4 TSEN15 UBXN11 USH1C USH1G USHBP1 USP20 VBP1 VPS37B VWC2 WDR62 WWOX YWHAE ZBTB14 ZC2HC1C ZFP90 ZNF143 ZNF426 ZNF511 ZNF581 ZNF76 ZRANB1
Entrez ID		11332	84080
HPRD ID		12517	13151
Ensembl ID		ENSG00000097021	ENSG00000124074
Uniprot IDs		O00154	Q9H0I2
PDB IDs		2QQ2
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Shelterin Complex Negative Regulation Of Metabolic Process Nuclear Telomere Cap Complex Identical Protein Binding Regulation Of Primary Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Telomere Capping Negative Regulation Of Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Cellular Component Organization Nucleus Regulation Of ERAD Pathway Telomeric DNA Binding Regulation Of Response To Endoplasmic Reticulum Stress Negative Regulation Of Telomere Maintenance Via Telomere Lengthening POZ Domain Binding Negative Regulation Of DNA Biosynthetic Process Telomere Assembly Regulation Of Metabolic Process Nuclear Pore Localization Regulation Of Telomere Maintenance Negative Regulation Of Telomere Maintenance Polyubiquitin Modification-dependent Protein Binding Muscle Organ Development Regulation Of Telomere Maintenance Via Telomerase Muscle Structure Development Negative Regulation Of DNA-templated Transcription Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of RNA Biosynthetic Process Cellular Component Assembly Telomeric D-loop Disassembly G-rich Strand Telomeric DNA Binding Telomeric Loop Disassembly Organelle Organization Positive Regulation Of Telomere Maintenance Negative Regulation Of Chromosome Organization Regulation Of Organelle Organization Regulation Of DNA Biosynthetic Process Positive Regulation Of ERAD Pathway Regulation Of Macromolecule Biosynthetic Process Regulation Of Stress Fiber Assembly Regulation Of Chromosome Organization Negative Regulation Of Transcription By RNA Polymerase II Telomere Maintenance Telomere Maintenance Via Telomerase	Protein Binding Intermediate Filament Identical Protein Binding Keratin Filament Cytoskeleton Cytosol Intermediate Filament Organization Nucleus Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization
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