ACOT7 and ACOT12

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ACOT7	ACOT12
Description		acyl-CoA thioesterase 7	acyl-CoA thioesterase 12
Image
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Cytosol Extracellular Exosome	Nucleoplasm Cytoplasm Cytosol Intercellular Bridge
	Molecular Function	Fatty-acyl-CoA Binding Protein Binding Hydrolase Activity Thiolester Hydrolase Activity Long-chain Fatty Acyl-CoA Binding Protein Homodimerization Activity Fatty Acyl-CoA Hydrolase Activity Carboxylic Ester Hydrolase Activity Long-chain Fatty Acyl-CoA Hydrolase Activity	Acetyl-CoA Hydrolase Activity Protein Binding ATP Binding Lipid Binding Hydrolase Activity Thiolester Hydrolase Activity Identical Protein Binding Carboxylic Ester Hydrolase Activity
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Acyl-CoA Metabolic Process Fatty Acid Catabolic Process Coenzyme A Biosynthetic Process Medium-chain Fatty-acyl-CoA Catabolic Process Long-chain Fatty-acyl-CoA Catabolic Process Medium-chain Fatty Acid Biosynthetic Process Palmitic Acid Biosynthetic Process	Acetyl-CoA Metabolic Process Lipid Metabolic Process Fatty Acid Metabolic Process Acyl-CoA Metabolic Process
Pathways		Mitochondrial Fatty Acid Beta-Oxidation	Mitochondrial Fatty Acid Beta-Oxidation
Drugs
Diseases
GWAS		A body shape index ( 34021172) Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) HDL cholesterol levels in HIV infection ( 33109212) Metabolite levels ( 31628463) QT interval ( 19305408) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172)	Bipolar disorder ( 31043756)
Interacting Genes		26 interacting genes: ACOT12 ATXN1 ATXN1L BAG4 CAMK2B CDC42 CRYAB DAZAP2 DLC1 ENKD1 FXR1 HOXA1 LMNA MAGEA3 MAGEA6 NCOA5 POT1 POU6F1 SPATC1L TERF1 THAP1 TINF2 UBQLN1 UBQLN2 UBXN1 ZNF438	9 interacting genes: ACOT7 MEOX1 MEOX2 NAA10 NAA11 PAX5 PAX6 REL ZBTB8A
Entrez ID		11332	134526
HPRD ID		12517	16680
Ensembl ID		ENSG00000097021	ENSG00000172497
Uniprot IDs		O00154	Q8WYK0
PDB IDs		2QQ2	3B7K 4MOB 4MOC
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Shelterin Complex Negative Regulation Of Metabolic Process Nuclear Telomere Cap Complex Identical Protein Binding Regulation Of Primary Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Telomere Capping Negative Regulation Of Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Cellular Component Organization Nucleus Regulation Of ERAD Pathway Telomeric DNA Binding Regulation Of Response To Endoplasmic Reticulum Stress Negative Regulation Of Telomere Maintenance Via Telomere Lengthening POZ Domain Binding Negative Regulation Of DNA Biosynthetic Process Telomere Assembly Regulation Of Metabolic Process Nuclear Pore Localization Regulation Of Telomere Maintenance Negative Regulation Of Telomere Maintenance Polyubiquitin Modification-dependent Protein Binding Muscle Organ Development Regulation Of Telomere Maintenance Via Telomerase Muscle Structure Development Negative Regulation Of DNA-templated Transcription Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of RNA Biosynthetic Process Cellular Component Assembly Telomeric D-loop Disassembly G-rich Strand Telomeric DNA Binding Telomeric Loop Disassembly Organelle Organization Positive Regulation Of Telomere Maintenance Negative Regulation Of Chromosome Organization Regulation Of Organelle Organization Regulation Of DNA Biosynthetic Process Positive Regulation Of ERAD Pathway Regulation Of Macromolecule Biosynthetic Process Regulation Of Stress Fiber Assembly Regulation Of Chromosome Organization Negative Regulation Of Transcription By RNA Polymerase II Telomere Maintenance Telomere Maintenance Via Telomerase	Protein-N-terminal-alanine Acetyltransferase Activity Protein-N-terminal-glutamate Acetyltransferase Activity Protein N-terminal-serine Acetyltransferase Activity DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Somite Specification RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding NatA Complex Protein-N-terminal Amino-acid Acetyltransferase Activity DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity HMG Box Domain Binding N-terminal Protein Amino Acid Acetylation Segment Specification Somite Development Sequence-specific DNA Binding Chromatin Protein Acetylation Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Positive Regulation Of Transcription By RNA Polymerase II DNA Binding Embryonic Pattern Specification Regulation Of Transcription By RNA Polymerase II Forebrain-midbrain Boundary Formation Pancreatic A Cell Development Negative Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric Long-chain Fatty-acyl-CoA Catabolic Process Palmitic Acid Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Cerebral Cortex Development Pattern Specification Process Positive Regulation Of RNA Metabolic Process Sclerotome Development Habenula Development Pallium Development Medium-chain Fatty Acid Biosynthetic Process Medium-chain Fatty-acyl-CoA Catabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Embryonic Organ Morphogenesis Regulation Of Asymmetric Cell Division Oligodendrocyte Cell Fate Specification NF-kappaB Complex Long-chain Fatty Acyl-CoA Binding Medium-chain Fatty-acyl-CoA Metabolic Process Nucleus Forebrain Dorsal/ventral Pattern Formation Regulation Of Centromeric Sister Chromatid Cohesion Negative Regulation Of Sister Chromatid Cohesion
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?