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DCAF8
Gene Name
DDB1 and CUL4 associated factor 8
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Cul4-RING E3 Ubiquitin Ligase Complex
Molecular Function
Protein Binding
Biological Process
Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions
9 interactors:
DDB1
GTPBP3
MDFI
PRMT1
PRMT8
RAF1
RBPMS
SUV39H1
THAP1
Entrez ID
50717
HPRD ID
18300
Ensembl ID
ENSG00000132716
Uniprot IDs
B7Z8C9
Q5TAQ9
PDB IDs
3I8E
Enriched GO Terms of Interacting Partners
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Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine
Histone Modification
Peptidyl-arginine N-methylation
Histone Methylation
Histone H4-R3 Methylation
Histone Arginine Methylation
Peptidyl-arginine Methylation
Protein Methylation
Chromatin Modification
Chromatin Organization
Chromosome Organization
Death-inducing Signaling Complex Assembly
Methylation
Regulation Of Nitrogen Compound Metabolic Process
Cellular Metabolic Process
Positive Regulation By Virus Of Viral Protein Levels In Host Cell
Regulation Of Transcription, DNA-templated
Regulation Of Protein Import Into Nucleus
Negative Regulation Of Megakaryocyte Differentiation
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Positive Regulation Of Protein Phosphorylation
Regulation Of RNA Metabolic Process
Regulation Of Protein Localization To Nucleus
Histone H3-K9 Dimethylation
UV-damage Excision Repair
Regulation Of Nucleocytoplasmic Transport
Positive Regulation Of Viral Release From Host Cell
MAPK Cascade
Organelle Organization
Positive Regulation Of Phosphorylation
Cellular Protein Modification Process
Negative Regulation Of Hematopoietic Progenitor Cell Differentiation
Regulation Of Gene Expression
Positive Regulation Of Protein Modification Process
Regulation Of Binding
Regulation Of Intracellular Protein Transport
Histone H3-K9 Trimethylation
Peptidyl-amino Acid Modification
Activation Of Protein Kinase Activity
Peptidyl-lysine Dimethylation
Histone H2A Monoubiquitination
Signal Transduction By Phosphorylation
Response To Hypoxia
Positive Regulation Of SMAD Protein Import Into Nucleus
Regulation Of Metabolic Process
Histone H2A Ubiquitination
Regulation Of Protein Phosphorylation
Chromatin Silencing At RDNA
Regulation Of SMAD Protein Import Into Nucleus
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