HOXD4 and SNAI1

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		HOXD4	SNAI1
Gene Name		homeobox D4	snail family zinc finger 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Cytoplasm
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Protein Binding Kinase Binding Metal Ion Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Multicellular Organismal Development	Negative Regulation Of Transcription From RNA Polymerase II Promoter Osteoblast Differentiation Mesoderm Formation Epithelial To Mesenchymal Transition Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Vitamin D Biosynthetic Process Cell Migration Positive Regulation Of Cell Migration Hair Follicle Morphogenesis Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Transcription, DNA-templated Palate Development Cartilage Morphogenesis Trophoblast Giant Cell Differentiation Negative Regulation Of Cell Differentiation Involved In Embryonic Placenta Development Left/right Pattern Formation Notch Signaling Involved In Heart Development Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Tight Junction Assembly
Pathways
Drugs
Diseases
GWAS			Psoriasis ( 20953189)
Protein-Protein Interactions		19 interactors: ASB8 CNOT7 CREBBP DEDD EP300 ETV4 HIPK1 HNRNPAB HOXB13 MEIS1 PBX1 RNPS1 RXRG SNAI1 TIGD4 XRCC6 ZBTB32 ZMYND11 ZSCAN18	19 interactors: ACTN2 CTDSP1 CTDSP2 CTDSPL FBXL14 FBXL5 GSK3B HIST1H3A HOXD4 KRT31 KRT40 KRTAP10-3 LATS2 MID2 MTUS2 NOTCH1 NOTCH2NL RCOR1 TRIM23
Entrez ID		3233	6615
HPRD ID		00864	05025
Ensembl ID		ENSG00000170166	ENSG00000124216
Uniprot IDs		P09016	O95863
PDB IDs			2Y48
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Organ Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Tissue Development N-terminal Peptidyl-lysine Acetylation Multicellular Organismal Development Negative Regulation Of Biosynthetic Process Stem Cell Differentiation Anatomical Structure Development Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Process Organ Morphogenesis System Development Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process Developmental Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Anatomical Structure Morphogenesis Positive Regulation Of Type I Interferon Production Stem Cell Development N-terminal Protein Amino Acid Acetylation Cell Differentiation	Negative Regulation Of Protein Phosphorylation Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Phosphorylation Protein Localization To Microtubule Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Metabolic Process Cellular Protein Modification Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Protein Localization To Cytoskeleton Cellular Protein Metabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cell Cycle Regulation Of Hematopoietic Progenitor Cell Differentiation Negative Regulation Of Protein Metabolic Process Negative Regulation Of Neuron Differentiation Negative Regulation Of Wnt Signaling Pathway Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Regulation Of Canonical Wnt Signaling Pathway Regulation Of Cell Cycle Phase Transition Protein Ubiquitination Regulation Of Protein Phosphorylation Wound Healing Positive Regulation Of Stem Cell Differentiation Protein Modification By Small Protein Conjugation Epithelial To Mesenchymal Transition Epidermis Development Venous Endothelial Cell Differentiation Notch Signaling Pathway Involved In Regulation Of Secondary Heart Field Cardioblast Proliferation Protein Metabolic Process Negative Regulation Of Neurogenesis Regulation Of Developmental Growth Response To Wounding Regulation Of Wnt Signaling Pathway Regulation Of Cellular Protein Metabolic Process Regulation Of Phosphorylation Negative Regulation Of Cell Development Negative Regulation Of Type B Pancreatic Cell Development Vasculogenesis Involved In Coronary Vascular Morphogenesis Cardiac Right Atrium Morphogenesis Mitral Valve Formation Superior Temporal Gyrus Development Negative Regulation Of Biosynthetic Process Keratinocyte Differentiation Regulation Of Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of Protein Metabolic Process
Tagcloud ?		allowed canonical confers cos developmentally dnase element embryogenesis embryonal enhancer footprinting heterologous mimic morphogens nevertheless nt2 polyadenylation proper rars reproduces responsive retinoids sequential spatially specifying start temporally transactivated	aberrations apart aspect ccnd1 clinicopathological copy covered encompassed endometrial erbb1 erbb2 erbb3 erbb4 esr1 frequent infiltration insufficient myometrial pakt1 pgr pik3ca prom1 rad21 rad27 runx1 scgb2a2 snai2 top2a younger
Tagcloud (Difference) ?		allowed canonical confers cos developmentally dnase element embryogenesis embryonal enhancer footprinting heterologous mimic morphogens nevertheless nt2 polyadenylation proper rars reproduces responsive retinoids sequential spatially specifying start temporally transactivated	aberrations apart aspect ccnd1 clinicopathological copy covered encompassed endometrial erbb1 erbb2 erbb3 erbb4 esr1 frequent infiltration insufficient myometrial pakt1 pgr pik3ca prom1 rad21 rad27 runx1 scgb2a2 snai2 top2a younger
Tagcloud (Intersection) ?