HOXA1 and PBX2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		HOXA1	PBX2
Gene Name		homeobox A1	pre-B-cell leukemia homeobox 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Transcription Factor Complex
	Molecular Function	Protein Binding Sequence-specific DNA Binding	Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Factor Binding Sequence-specific DNA Binding
	Biological Process	Transcription, DNA-templated Multicellular Organismal Development Sensory Perception Of Sound Optokinetic Behavior Motor Neuron Axon Guidance Anatomical Structure Morphogenesis Anterior/posterior Pattern Specification Rhombomere 3 Development Rhombomere 4 Development Rhombomere 5 Development Abducens Nerve Formation Facial Nerve Structural Organization Facial Nucleus Development Central Nervous System Neuron Differentiation Outer Ear Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Neurocranium Morphogenesis Inner Ear Development Artery Morphogenesis Regulation Of Behavior Cognition Neuromuscular Process Artery Development Semicircular Canal Formation Cellular Response To Retinoic Acid Cochlea Development Cochlea Morphogenesis	Transcription, DNA-templated Proximal/distal Pattern Formation Embryonic Limb Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS			Asthma ( 21804548) Crohn's disease ( 23266558) Prostate cancer ( 23535732)
Protein-Protein Interactions		79 interactors: ABHD17A ADAMTSL4 ALG13 BLZF1 C1orf94 CCDC33 CHIC2 CHRD CRACR2A DUSP22 EFEMP2 FAM154A FHL5 GATA1 GP9 GRN HOXD3 HSFY1 IKZF2 KDM1A KRT31 KRT38 KRT40 KRT81 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP12-4 KRTAP26-1 KRTAP3-2 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE3E LCE4A LGALS13 LIMS1 LNX2 LPXN MDFI MGAT5B N4BP2L2 NOTCH2NL PBX1 PBX2 PCSK5 PDCD6IP PIK3R1 PITX2 PKNOX1 PLSCR1 PLSCR4 PRMT6 PRRC2B RAB33A RBPMS RGS17 RGS20 SDCBP SPRY1 SUV39H1 TBC1D10C TCF3 TRAF1 TRAPPC6A TRIM42 TRIP6 ZZZ3	21 interactors: BAIAP2 BLOC1S1 CARD9 CCDC88B CENPBD1 COPS6 DCTN3 HOXA1 HOXA9 HOXB8 IKBKAP MCRS1 NUP62 PBX1 PKNOX1 RPL4 RPS6KC1 SKIV2L2 SMYD3 UBE2E1 ZDHHC7
Entrez ID		3198	5089
HPRD ID		00843	08890
Ensembl ID		ENSG00000105991	ENSG00000204304
Uniprot IDs		P49639	P40425
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Embryo Development Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Pattern Specification Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of Signal Transduction Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Positive Regulation Of Gene Expression Epidermis Development Positive Regulation Of Extracellular Vesicular Exosome Assembly Regulation Of DNA Binding Regulation Of Protein Import Into Nucleus Regulation Of Transcription Factor Import Into Nucleus Regulation Of Signaling Regulation Of Extracellular Vesicular Exosome Assembly Regulation Of Protein Localization To Nucleus Developmental Process Regulation Of Nucleocytoplasmic Transport Negative Regulation Of Signal Transduction Biosynthetic Process RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Negative Regulation Of DNA Binding Keratinization Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Signaling Epidermal Cell Differentiation Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Phospholipid Scrambling Regulation Of Intracellular Protein Transport Gene Expression Regulation Of Cell Proliferation Positive Regulation Of Cellular Metabolic Process Blood Coagulation	Embryonic Skeletal System Development RNA Biosynthetic Process Anterior/posterior Pattern Specification RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription, DNA-templated Cellular Metabolic Process Pattern Specification Process Proximal/distal Pattern Formation Skeletal System Development Abducens Nerve Formation Optokinetic Behavior Immune System Process Peptidyl-lysine Modification Nucleobase-containing Compound Metabolic Process Embryonic Morphogenesis Negative Regulation Of Transferase Activity Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Facial Nucleus Development Organelle Organization Cellular Protein Modification Process Chromatin Organization Negative Regulation Of Myeloid Cell Differentiation Cellular Nitrogen Compound Metabolic Process Viral Transcription Rhombomere 4 Development Semicircular Canal Formation Positive Regulation Of Cellular Metabolic Process Chordate Embryonic Development Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Embryo Development Ending In Birth Or Egg Hatching Regulation Of Nucleic Acid-templated Transcription Rhombomere 3 Development Rhombomere 5 Development Regulation Of RNA Biosynthetic Process Cellular Protein Metabolic Process Histone Modification Cellular Process Regulation Of RNA Metabolic Process Membrane Organization Peptidyl-L-cysteine S-palmitoylation Peptidyl-lysine Acetylation Endomembrane System Organization Embryonic Skeletal System Morphogenesis Nitrogen Compound Metabolic Process
Tagcloud ?		divergence embryo embryos exert gsc illustrate introduced liganded ligands malformations microinjection nevertheless pleiotropic possess posterior rar reporter responsive responsiveness retinoid retinoids rxr selective striking vertebrate vertebrates xenopus xlim zebrafish	associate buds embryo embryonal embryonic endodermal extended half hox increases limb lives meis mrna mrnas p19 pbx1 pbx1a pbx1b pbx3 pbxs proteasome ra requiring stabilization subtype transcriptionally unspecific
Tagcloud (Difference) ?		divergence embryos exert gsc illustrate introduced liganded ligands malformations microinjection nevertheless pleiotropic possess posterior rar reporter responsive responsiveness retinoid retinoids rxr selective striking vertebrate vertebrates xenopus xlim zebrafish	associate buds embryonal embryonic endodermal extended half hox increases limb lives meis mrna mrnas p19 pbx1 pbx1a pbx1b pbx3 pbxs proteasome ra requiring stabilization subtype transcriptionally unspecific
Tagcloud (Intersection) ?		embryo