PBX2 and HOXB8

Number of citations of the paper that reports this interaction (PMID 11438208)
12

Data Source:
HPRD (in vitro, in vivo)

		PBX2	HOXB8
Gene Name		pre-B-cell leukemia homeobox 2	homeobox B8
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex	Nucleus
	Molecular Function	Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Factor Binding Sequence-specific DNA Binding	Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding
	Biological Process	Transcription, DNA-templated Proximal/distal Pattern Formation Embryonic Limb Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Grooming Behavior Adult Locomotory Behavior Anterior/posterior Pattern Specification Sensory Perception Of Pain Dorsal Spinal Cord Development Negative Regulation Of Myeloid Cell Differentiation Embryonic Skeletal System Morphogenesis
Pathways
Drugs
Diseases
GWAS		Asthma ( 21804548) Crohn's disease ( 23266558) Prostate cancer ( 23535732)
Protein-Protein Interactions		21 interactors: BAIAP2 BLOC1S1 CARD9 CCDC88B CENPBD1 COPS6 DCTN3 HOXA1 HOXA9 HOXB8 IKBKAP MCRS1 NUP62 PBX1 PKNOX1 RPL4 RPS6KC1 SKIV2L2 SMYD3 UBE2E1 ZDHHC7	4 interactors: MEIS1 PBX1 PBX2 PBX3
Entrez ID		5089	3218
HPRD ID		08890	00851
Ensembl ID		ENSG00000204304	ENSG00000120068
Uniprot IDs		P40425	I3L3R1 P17481 Q8N8T3
PDB IDs
Enriched GO Terms of Interacting Partners?		Embryonic Skeletal System Development RNA Biosynthetic Process Anterior/posterior Pattern Specification RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription, DNA-templated Cellular Metabolic Process Pattern Specification Process Proximal/distal Pattern Formation Skeletal System Development Abducens Nerve Formation Optokinetic Behavior Immune System Process Peptidyl-lysine Modification Nucleobase-containing Compound Metabolic Process Embryonic Morphogenesis Negative Regulation Of Transferase Activity Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Facial Nucleus Development Organelle Organization Cellular Protein Modification Process Chromatin Organization Negative Regulation Of Myeloid Cell Differentiation Cellular Nitrogen Compound Metabolic Process Viral Transcription Rhombomere 4 Development Semicircular Canal Formation Positive Regulation Of Cellular Metabolic Process Chordate Embryonic Development Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Embryo Development Ending In Birth Or Egg Hatching Regulation Of Nucleic Acid-templated Transcription Rhombomere 3 Development Rhombomere 5 Development Regulation Of RNA Biosynthetic Process Cellular Protein Metabolic Process Histone Modification Cellular Process Regulation Of RNA Metabolic Process Membrane Organization Peptidyl-L-cysteine S-palmitoylation Peptidyl-lysine Acetylation Endomembrane System Organization Embryonic Skeletal System Morphogenesis Nitrogen Compound Metabolic Process	Proximal/distal Pattern Formation Pattern Specification Process Transcription, DNA-templated RNA Biosynthetic Process Posterior Compartment Specification Anterior Compartment Pattern Formation Embryonic Limb Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Limb Morphogenesis RNA Metabolic Process Negative Regulation Of Neuron Differentiation Limb Development Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Anterior/posterior Pattern Specification Positive Regulation Of Transcription, DNA-templated Compartment Pattern Specification Negative Regulation Of Neurogenesis Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Generation Of Neurons Regulation Of Transcription, DNA-templated Negative Regulation Of Cell Development Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of RNA Metabolic Process Neurogenesis Nucleobase-containing Compound Metabolic Process Multicellular Organismal Development Cell Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Biosynthetic Process Regulation Of Gene Expression Anatomical Structure Development Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Respiratory Gaseous Exchange By Neurological System Process Regulation Of Respiratory System Process Megakaryocyte Development Developmental Process Nitrogen Compound Metabolic Process Regulation Of Neuron Differentiation Skeletal System Development Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Nervous System Development Dorsal Spinal Cord Development
Tagcloud ?		associate buds embryo embryonal embryonic endodermal extended half hox increases limb lives meis mrna mrnas p19 pbx1 pbx1a pbx1b pbx3 pbxs proteasome ra requiring stabilization subtype transcriptionally unspecific	6c 6g c4 carbohydrate cd11b complement declined dendritic deposited fashion ficolin ficolins granular granulocytes granulocytic immature int intra lectin ly lysates macrophages masp neutrophilic orthologue producer sepsis stored supernatants
Tagcloud (Difference) ?		associate buds embryo embryonal embryonic endodermal extended half hox increases limb lives meis mrna mrnas p19 pbx1 pbx1a pbx1b pbx3 pbxs proteasome ra requiring stabilization subtype transcriptionally unspecific	6c 6g c4 carbohydrate cd11b complement declined dendritic deposited fashion ficolin ficolins granular granulocytes granulocytic immature int intra lectin ly lysates macrophages masp neutrophilic orthologue producer sepsis stored supernatants
Tagcloud (Intersection) ?