HOXA1 and RBPMS

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		HOXA1	RBPMS
Description		homeobox A1	RNA binding protein, mRNA processing factor
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	P-body Nucleus Nucleoplasm Cytoplasm Cytosol Cytoplasmic Stress Granule
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	Nucleic Acid Binding Transcription Coactivator Activity RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Pre-mRNA Binding Identical Protein Binding Protein Homodimerization Activity Molecular Adaptor Activity Pre-mRNA Intronic Binding MRNA CDS Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Sensory Perception Of Sound Optokinetic Behavior Anatomical Structure Morphogenesis Abducens Nerve Formation Outer Ear Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Embryonic Neurocranium Morphogenesis Inner Ear Development Artery Morphogenesis Regulation Of Behavior Cognition Neuromuscular Process Artery Development Semicircular Canal Formation Cochlea Development Cochlea Morphogenesis	Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Processing Response To Oxidative Stress Positive Regulation Of DNA-templated Transcription SMAD Protein Signal Transduction Protein-containing Complex Assembly
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases		Bosley-Salih-Alorainy syndrome and Athabascan brainstem dysgenesis syndrome
GWAS		Chronic venous disease ( 28374850) Macular thickness ( 30535121) Multiple sclerosis ( 31604244) Small cell lung carcinoma ( 28604730) Tonsillectomy ( 27182965 28928442)	Blood urea nitrogen levels ( 31152163) Breast size ( 27182965) Eosinophil count ( 32888494) Granulocyte count ( 27863252) Heart rate variability traits ( 22174390) Lymphocyte percentage of white cells ( 27863252 32888494) Mean corpuscular hemoglobin ( 27863252 32888494 28017375) Mean corpuscular volume ( 29403010 32888494 28017375 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252 32888494) Neutrophil percentage of white cells ( 32888494) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494 27863252) PR interval ( 32439900) Serum alkaline phosphatase levels ( 33547301) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Systolic blood pressure ( 30224653) Total grey matter volume ( 31530798) White blood cell count ( 32888494)
Interacting Genes		344 interacting genes: ACOT7 ADAM12 ADAMTSL2 ADAMTSL4 AGAP3 AGRN AGXT ALG13 ALPP AMMECR1 AMOT ANKS1A ARID5A ARMC7 ATG9B ATP23 ATXN2L BAG4 BAHD1 BATF2 BEND5 BLCAP BLZF1 BSCL2 BSDC1 BUD31 C11orf16 CATSPER1 CCDC120 CCDC33 CCN3 CCN4 CCN5 CCNK CD163 CD164 CDPF1 CERCAM CFAP68 CFP CHIC2 CHRD CHRDL2 CIRSR CNFN CNNM3 COL8A1 CREB5 CRELD1 CRELD2 CUTA CXCL16 CYP21A2 CYSRT1 DBF4B DCTN1 DGKQ DKK3 DOCK2 DOCK3 DOK3 DRC4 DTX2 DUSP10 DUSP22 EEF1A1 EFEMP1 EFEMP2 EGFL7 ENKD1 EPDR1 ESM1 ESR2 EVA1B FAAP100 FAM219B FAM221A FBLN1 FBLN2 FBLN5 FBN1 FHL3 FHL5 FN1 FOXH1 FOXN1 FRS3 FST FUCA2 GATA1 GCM2 GDF15 GNE GP9 GPRASP3 GPS2 GRN GSTP1 GUCD1 HEXB HEXIM2 HEY2 HOXB9 HR HSD3B7 ID3 IGFL1 IGFN1 INCA1 INO80B IRX6 ITGB4 JAG2 KCTD9 KDM1A KPRP KRT31 KRT33B KRT34 KRT35 KRT37 KRT38 KRT40 KRT81 KRT82 KRT83 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-3 KRTAP10-4 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP13-2 KRTAP13-3 KRTAP13-4 KRTAP15-1 KRTAP19-6 KRTAP19-7 KRTAP2-3 KRTAP2-4 KRTAP23-1 KRTAP26-1 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP4-7 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LAMA5 LAMB2 LASP1 LCE1A LCE1B LCE1C LCE1D LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3C LCE3D LCE3E LCE4A LCE5A LGALS13 LGALS4 LIMS2 LMX1B LNX1 LONRF1 LPXN LTBP1 LTBP3 LTBP4 LUC7L2 MACO1 MAPKBP1 MDFI MEGF6 MEGF8 MFAP2 MGAT5B MKRN3 MLLT11 MYO15B MYPOP N4BP2L2 NBPF19 NCK2 NECTIN2 NEDD9 NEK6 NELL1 NELL2 NFKBID NOTCH1 NOTCH2NLA NOTCH3 NR1D2 NTN4 NUCB1 NXF1 ODF1 OIT3 OPLAH OTX1 P2RY6 PAX6 PBX2 PCSK5 PCYOX1 PCYT2 PHETA1 PIK3R1 PIN1 PITX1 PITX2 PKM PKNOX1 PLA2G10 PLEKHN1 PLLP PLSCR1 PLSCR2 PLSCR3 PLSCR4 PRICKLE4 PRMT6 PROP1 PSMB1 PTH1R PVR PYCR3 QARS1 R3HDM1 RALGDS RANBP3 RBCK1 RBP3 RBPMS RCHY1 RGS17 RGS19 RGS20 RNF208 RSPO2 RTN4R SAXO4 SCT SDCBP SIVA1 SLC15A3 SLC23A1 SLIT1 SLIT2 SLPI SMCP SND1 SNRPB SNRPC SPATA12 SPATA18 SPRY1 SPRY2 SPRY3 SPRY4 SSC4D SSUH2 STX11 SUV39H1 TBC1D10C TBR1 TBX15 TCF19 TCF3 TEKT4 TEKT5 TGFB1 TGFB1I1 TGM7 THAP7 TLE5 TNS2 TRAF1 TRAF2 TRAF4 TRAPPC6A TRIM42 TRIM55 TRIM63 TRIM8 TRIP6 TSPAN4 UBL5 UNKL VASN VWC2 VWC2L VWCE VWF WDR83 WWOX YIPF3 YPEL3 ZBTB16 ZFTRAF1 ZIM2 ZMAT1 ZNF417 ZNF587 ZNF688 ZNF774 ZNF837 ZNF843 ZNRF3	311 interacting genes: ABCF3 ACTMAP ADAM15 ALG13 AMMECR1 ANAPC11 ANKHD1 ANKMY1 APLN ARHGAP9 ARHGEF39 ARID5A ATN1 ATP6V0D1 ATP6V0E2 ATXN1 ATXN7L2 BAG4 BANP BBS2 BCAS2 BCL6B BHLHE40 BOLL C10orf55 C11orf87 C1orf94 C22orf39 CAMK2A CAMK2B CCDC120 CCER1 CCL14 CCNG1 CCNK CDC23 CDC42EP1 CDK6 CEP55 CHCHD7 CIMIP1 CIMIP2B CLPP CNNM3 COL8A1 CPEB2 CPSF7 CRBN CREB5 CRX CRYBA1 CSN3 CSNK1G2-AS1 CYBA DAZAP2 DCAF8 DCDC2B DCTN5 DDX28 DMRT3 DMRTB1 DNTTIP2 DOK3 DOK6 DPYSL4 DTX2 DVL2 DYNC1I1 EAF2 EFEMP2 ENKD1 EWSR1 EXOSC1 EXOSC7 EYA2 FAM120A FAM124B FAM168A FASTK FBF1 FBXL18 FNDC11 FOXC2 FOXP3 FOXS1 FRG1 FXR2 GATA1 GATA2 GATAD2B GCM2 GLIS2 GLYCTK GPATCH2L GPS2 GRAP GRAP2 GSE1 HCK HEY2 HEYL HIVEP1 HNRNPLL HOXA1 HOXA9 HOXB9 HOXC8 HSFY1 IGF2 ILF3 INCA1 INIP IP6K2 KAT5 KCTD9 KIF1A KIR2DL4 KLHDC7B KPNA2 KRAS KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-4 KRTAP13-1 KRTAP13-3 KRTAP15-1 KRTAP19-1 KRTAP19-3 KRTAP19-5 KRTAP19-7 KRTAP23-1 KRTAP26-1 KRTAP3-1 KRTAP8-1 LARP4B LASP1 LGALS9C LINC00482 LINC00588 LINC00908 LINC01547 LINC01588 LMO4 LONRF1 LRRC41 LZTS2 MAGED1 MAZ MBNL1 MBNL2 MCM5 MCM7 MEIS2 MGAT5B MKRN3 MLLT10 MORN3 MRPL10 MRPL20-AS1 MRPL44 MSI2 MSX1 MVP MYH7B MYO1C MYOZ2 NAB2 NANOG NAPRT NEDD9 NEU4 NIP7 NKX2-5 NR1D2 NTAQ1 NXF1 NYNRIN OTX1 PATL1 PATZ1 PCBP2 PDLIM4 PER1 PGLS PHF1 PICALM PIH1D1 PIN1 PITX1 PITX2 PKP2 PLAC8 PLSCR4 POGZ POLDIP3 POLR3GL POM121 POU4F2 POU6F2 PPP1R16B PRKAA1 PRKAA2 PRKAB2 PRKRA PRPF6 PRR20A PRR20B PRR20C PRR20D PRR20E PRR35 PRRC2B PSG11 PSMF1 PTBP3 QKI R3HDM2 RABL6 RAD54L2 RAMAC RBFOX1 RBFOX2 RBM22 RBM24 RBM42 RBM46 RBM7 RBPMS2 RDH12 RDX RHOBTB3 RHOXF2 RIPPLY1 RNF20 ROR2 RPP25 RPS27A RTP5 RUSC1 SBF2 SEMA4G SERF2 SF1 SFI1 SH3RF2 SIRPB1 SLAIN1 SLC25A48 SLIRP SMAD3 SMAP1 SMARCC2 SMUG1 SNHG29 SNRPB SNRPC SNRPG SNRPN SNW1 SPATA46 SPATA8 SPG7 SPMIP6 SPMIP9 STRBP TBX6 TCEA2 TCF7L2 TEKT5 TENT2 TFG TIE1 TINAGL1 TLE5 TMEM277P TMEM42 TMSB4X TNS2 TOLLIP TOR1AIP2 TRAF4 TRIP13 TSC1 TSG101 TSGA10IP TSPYL6 TTLL10 TUSC2 TXNL4A UBAP2 UNKL VENTX VEZF1 VGLL3 VHL VHLL VPS37C WBP4 WDR54 WDR90 YPEL3 YTHDF1 ZBTB32 ZC3H10 ZIC1 ZMAT5 ZNF34 ZNF385C ZNF488 ZNF581
Entrez ID		3198	11030
HPRD ID		00843	11870
Ensembl ID		ENSG00000105991	ENSG00000157110
Uniprot IDs		E7ERT8 P49639	B4E3T4 Q93062
PDB IDs			5CYJ 5DET
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Keratinization Protein Binding Epidermis Development Extracellular Matrix Hair Cycle Extracellular Matrix Structural Constituent Structural Constituent Of Skin Epidermis Tissue Development Integrin Binding Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Calcium Ion Binding Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Intermediate Filament Organization Basement Membrane Microfibril Identical Protein Binding Regulation Of Cellular Response To Growth Factor Stimulus Developmental Process Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Animal Organ Morphogenesis Negative Regulation Of ERK1 And ERK2 Cascade Phospholipid Scramblase Activity Extracellular Region Morphogenesis Of An Epithelium Negative Regulation Of Cellular Response To Growth Factor Stimulus Plasma Membrane Phospholipid Scrambling Anatomical Structure Morphogenesis Elastic Fiber Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Structural Molecule Activity Tissue Morphogenesis Heparin Binding Roundabout Binding Embryonic Morphogenesis Extracellular Space Negative Regulation Of Biomineral Tissue Development Embryonic Hindlimb Morphogenesis Post-embryonic Eye Morphogenesis Extracellular Matrix Assembly Cell Fate Commitment TRAF2-GSTP1 Complex Vasculogenesis Lead Ion Binding Susceptibility To T Cell Mediated Cytotoxicity Lung Growth Regionalization Skeletal System Development	Nucleus Protein Binding RNA Binding Nucleic Acid Binding Negative Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleoplasm Positive Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Sequence-specific Double-stranded DNA Binding Intermediate Filament MRNA Processing Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression MRNA Binding Regulation Of Primary Metabolic Process RNA Processing Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Biosynthetic Process RNA Splicing Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of RNA Splicing Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Biosynthetic Process MRNA Metabolic Process Negative Regulation Of Biosynthetic Process RNA Metabolic Process MRNA Splicing, Via Spliceosome Chromatin Regulation Of Metabolic Process Spliceosomal Complex Negative Regulation Of Metabolic Process Cytoplasmic Stress Granule RNA Splicing, Via Transesterification Reactions RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of Metabolic Process
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