HOXA1 and GATA1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		HOXA1	GATA1
Gene Name		homeobox A1	GATA binding protein 1 (globin transcription factor 1)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Transcription Factor Complex Transcriptional Repressor Complex
	Molecular Function	Protein Binding Sequence-specific DNA Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription RNA Polymerase II Transcription Factor Binding Enhancer Sequence-specific DNA Binding P53 Binding DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Zinc Ion Binding DNA Binding, Bending Chromatin DNA Binding Sequence-specific DNA Binding C2H2 Zinc Finger Domain Binding
	Biological Process	Transcription, DNA-templated Multicellular Organismal Development Sensory Perception Of Sound Optokinetic Behavior Motor Neuron Axon Guidance Anatomical Structure Morphogenesis Anterior/posterior Pattern Specification Rhombomere 3 Development Rhombomere 4 Development Rhombomere 5 Development Abducens Nerve Formation Facial Nerve Structural Organization Facial Nucleus Development Central Nervous System Neuron Differentiation Outer Ear Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Neurocranium Morphogenesis Inner Ear Development Artery Morphogenesis Regulation Of Behavior Cognition Neuromuscular Process Artery Development Semicircular Canal Formation Cellular Response To Retinoic Acid Cochlea Development Cochlea Morphogenesis	Negative Regulation Of Transcription From RNA Polymerase II Promoter In Utero Embryonic Development Transcription From RNA Polymerase II Promoter Cell-cell Signaling Blood Coagulation Negative Regulation Of Cell Proliferation Male Gonad Development Regulation Of Glycoprotein Biosynthetic Process Regulation Of Definitive Erythrocyte Differentiation Erythrocyte Differentiation Megakaryocyte Differentiation Platelet Formation Basophil Differentiation Eosinophil Differentiation Negative Regulation Of Bone Mineralization Positive Regulation Of Osteoblast Proliferation Embryonic Hemopoiesis Eosinophil Fate Commitment Negative Regulation Of Apoptotic Process Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Erythrocyte Development Positive Regulation Of Peptidyl-tyrosine Phosphorylation Platelet Aggregation Transcriptional Activation By Promoter-enhancer Looping Dendritic Cell Differentiation Cellular Response To Thyroid Hormone Stimulus Negative Regulation Of Transcription Regulatory Region DNA Binding Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways			Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS
Protein-Protein Interactions		79 interactors: ABHD17A ADAMTSL4 ALG13 BLZF1 C1orf94 CCDC33 CHIC2 CHRD CRACR2A DUSP22 EFEMP2 FAM154A FHL5 GATA1 GP9 GRN HOXD3 HSFY1 IKZF2 KDM1A KRT31 KRT38 KRT40 KRT81 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP12-4 KRTAP26-1 KRTAP3-2 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE3E LCE4A LGALS13 LIMS1 LNX2 LPXN MDFI MGAT5B N4BP2L2 NOTCH2NL PBX1 PBX2 PCSK5 PDCD6IP PIK3R1 PITX2 PKNOX1 PLSCR1 PLSCR4 PRMT6 PRRC2B RAB33A RBPMS RGS17 RGS20 SDCBP SPRY1 SUV39H1 TBC1D10C TCF3 TRAF1 TRAPPC6A TRIM42 TRIP6 ZZZ3	51 interactors: AKT1 ARID1A CASP3 CCDC24 CEBPE CREBBP FBF1 FLI1 FRS3 HDAC3 HDAC4 HDAC5 HEXIM2 HEY1 HOXA1 HSPA4 KRTAP10-5 KRTAP9-2 LMO2 MAPK1 MAPK3 MAPK6 MED1 PRKAA1 PRKAB2 RADIL RAI1 SMARCA4 SMARCB1 SMARCC1 SMARCC2 SMARCD1 SMARCE1 SP1 SPI1 SPIB SRA1 STAT3 SUMO1 TAF7 TAL1 TAX1BP3 TRIM25 TRIM29 ZBTB16 ZBTB22 ZDHHC17 ZFPM1 ZFPM2 ZNF521 ZZZ3
Entrez ID		3198	2623
HPRD ID		00843	02372
Ensembl ID		ENSG00000105991	ENSG00000102145
Uniprot IDs		P49639	P15976
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Embryo Development Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Pattern Specification Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of Signal Transduction Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Positive Regulation Of Gene Expression Epidermis Development Positive Regulation Of Extracellular Vesicular Exosome Assembly Regulation Of DNA Binding Regulation Of Protein Import Into Nucleus Regulation Of Transcription Factor Import Into Nucleus Regulation Of Signaling Regulation Of Extracellular Vesicular Exosome Assembly Regulation Of Protein Localization To Nucleus Developmental Process Regulation Of Nucleocytoplasmic Transport Negative Regulation Of Signal Transduction Biosynthetic Process RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Negative Regulation Of DNA Binding Keratinization Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Signaling Epidermal Cell Differentiation Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Phospholipid Scrambling Regulation Of Intracellular Protein Transport Gene Expression Regulation Of Cell Proliferation Positive Regulation Of Cellular Metabolic Process Blood Coagulation	Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated Positive Regulation Of Gene Expression RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Gene Expression Cellular Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Macromolecule Biosynthetic Process Gene Expression RNA Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Biosynthetic Process Nucleosome Disassembly Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Developmental Process Chromatin Organization Regulation Of Cellular Process Anatomical Structure Development Chromatin Remodeling Myeloid Cell Differentiation Chromatin Modification Cell Differentiation Multicellular Organismal Development Embryonic Organ Development Hemopoiesis Chromosome Organization Megakaryocyte Differentiation Immune System Development
Tagcloud ?		divergence embryo embryos exert gsc illustrate introduced liganded ligands malformations microinjection nevertheless pleiotropic possess posterior rar reporter responsive responsiveness retinoid retinoids rxr selective striking vertebrate vertebrates xenopus xlim zebrafish	alls blasts cd3 cd45 comprised deregulation disrupted enable exploited fused haemopoietic immunocytochemical leukaemia leukaemic lymphoblastic lymphoid monocytes morphologically ordinately origin precursors rearrangement resembled sil tal tal1 transcripts unexplained unidentified
Tagcloud (Difference) ?		divergence embryo embryos exert gsc illustrate introduced liganded ligands malformations microinjection nevertheless pleiotropic possess posterior rar reporter responsive responsiveness retinoid retinoids rxr selective striking vertebrate vertebrates xenopus xlim zebrafish	alls blasts cd3 cd45 comprised deregulation disrupted enable exploited fused haemopoietic immunocytochemical leukaemia leukaemic lymphoblastic lymphoid monocytes morphologically ordinately origin precursors rearrangement resembled sil tal tal1 transcripts unexplained unidentified
Tagcloud (Intersection) ?