PBX2 and BLOC1S1

Number of citations of the paper that reports this interaction (PMID 14667819)
24

Data Source:
HPRD (two hybrid)

		PBX2	BLOC1S1
Gene Name		pre-B-cell leukemia homeobox 2	biogenesis of lysosomal organelles complex-1, subunit 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex	Extracellular Space Mitochondrial Intermembrane Space Mitochondrial Matrix Lysosomal Membrane Cytosol BLOC-1 Complex Extracellular Vesicular Exosome
	Molecular Function	Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Factor Binding Sequence-specific DNA Binding	Protein Binding
	Biological Process	Transcription, DNA-templated Proximal/distal Pattern Formation Embryonic Limb Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter	Post-Golgi Vesicle-mediated Transport Anterograde Axon Cargo Transport Aerobic Respiration Peptidyl-lysine Acetylation Neuron Projection Development Melanosome Organization Anterograde Synaptic Vesicle Transport Platelet Dense Granule Organization Membrane Organization
Pathways			Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding Lysosome Vesicle Biogenesis
Drugs
Diseases
GWAS		Asthma ( 21804548) Crohn's disease ( 23266558) Prostate cancer ( 23535732)
Protein-Protein Interactions		21 interactors: BAIAP2 BLOC1S1 CARD9 CCDC88B CENPBD1 COPS6 DCTN3 HOXA1 HOXA9 HOXB8 IKBKAP MCRS1 NUP62 PBX1 PKNOX1 RPL4 RPS6KC1 SKIV2L2 SMYD3 UBE2E1 ZDHHC7	13 interactors: APP BLOC1S2 BLOC1S3 BLOC1S4 BLOC1S5 BLOC1S6 HIST1H4A MTA1 NOTCH1 PBX2 PELP1 PTN SNAPIN
Entrez ID		5089	2647
HPRD ID		08890	03263
Ensembl ID		ENSG00000204304	ENSG00000135441
Uniprot IDs		P40425	P78537
PDB IDs
Enriched GO Terms of Interacting Partners?		Embryonic Skeletal System Development RNA Biosynthetic Process Anterior/posterior Pattern Specification RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription, DNA-templated Cellular Metabolic Process Pattern Specification Process Proximal/distal Pattern Formation Skeletal System Development Abducens Nerve Formation Optokinetic Behavior Immune System Process Peptidyl-lysine Modification Nucleobase-containing Compound Metabolic Process Embryonic Morphogenesis Negative Regulation Of Transferase Activity Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Facial Nucleus Development Organelle Organization Cellular Protein Modification Process Chromatin Organization Negative Regulation Of Myeloid Cell Differentiation Cellular Nitrogen Compound Metabolic Process Viral Transcription Rhombomere 4 Development Semicircular Canal Formation Positive Regulation Of Cellular Metabolic Process Chordate Embryonic Development Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Embryo Development Ending In Birth Or Egg Hatching Regulation Of Nucleic Acid-templated Transcription Rhombomere 3 Development Rhombomere 5 Development Regulation Of RNA Biosynthetic Process Cellular Protein Metabolic Process Histone Modification Cellular Process Regulation Of RNA Metabolic Process Membrane Organization Peptidyl-L-cysteine S-palmitoylation Peptidyl-lysine Acetylation Endomembrane System Organization Embryonic Skeletal System Morphogenesis Nitrogen Compound Metabolic Process	Anterograde Synaptic Vesicle Transport Axon Cargo Transport Melanosome Organization Pigment Granule Organization Anterograde Axon Cargo Transport Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Cellular Pigmentation Synaptic Vesicle Transport Pigmentation Microtubule-based Movement Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Neuron Projection Development Neuron Development Endosome To Melanosome Transport Pigment Granule Maturation Establishment Of Organelle Localization Cellular Pigment Accumulation Neuron Differentiation Cell Projection Organization Organelle Localization Microtubule-based Process Movement Of Cell Or Subcellular Component Synaptic Transmission Generation Of Neurons Nervous System Development Neurogenesis Melanosome Transport Pigment Granule Transport Cell Development Establishment Of Melanosome Localization Melanosome Localization Establishment Of Localization In Cell Secretion Of Lysosomal Enzymes Vesicle-mediated Transport Endosomal Transport Cell-cell Signaling Secretion By Cell Developmental Pigmentation Intracellular Transport Cellular Localization Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Platelet Dense Granule Organization Wound Healing Post-Golgi Vesicle-mediated Transport Secretion Multicellular Organismal Development Positive Regulation Of Pigment Cell Differentiation
Tagcloud ?		associate buds embryo embryonal embryonic endodermal extended half hox increases limb lives meis mrna mrnas p19 pbx1 pbx1a pbx1b pbx3 pbxs proteasome ra requiring stabilization subtype transcriptionally unspecific
Tagcloud (Difference) ?		associate buds embryo embryonal embryonic endodermal extended half hox increases limb lives meis mrna mrnas p19 pbx1 pbx1a pbx1b pbx3 pbxs proteasome ra requiring stabilization subtype transcriptionally unspecific
Tagcloud (Intersection) ?