HOXA1 and DUSP22

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		HOXA1	DUSP22
Gene Name		homeobox A1	dual specificity phosphatase 22
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Cytoplasm
	Molecular Function	Protein Binding Sequence-specific DNA Binding	Protein Tyrosine Phosphatase Activity Protein Tyrosine/serine/threonine Phosphatase Activity
	Biological Process	Transcription, DNA-templated Multicellular Organismal Development Sensory Perception Of Sound Optokinetic Behavior Motor Neuron Axon Guidance Anatomical Structure Morphogenesis Anterior/posterior Pattern Specification Rhombomere 3 Development Rhombomere 4 Development Rhombomere 5 Development Abducens Nerve Formation Facial Nerve Structural Organization Facial Nucleus Development Central Nervous System Neuron Differentiation Outer Ear Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Neurocranium Morphogenesis Inner Ear Development Artery Morphogenesis Regulation Of Behavior Cognition Neuromuscular Process Artery Development Semicircular Canal Formation Cellular Response To Retinoic Acid Cochlea Development Cochlea Morphogenesis	Negative Regulation Of Transcription From RNA Polymerase II Promoter Inactivation Of MAPK Activity Protein Dephosphorylation Apoptotic Process Transforming Growth Factor Beta Receptor Signaling Pathway Multicellular Organismal Development Cell Proliferation Peptidyl-tyrosine Dephosphorylation Regulation Of Cell Proliferation Positive Regulation Of JNK Cascade
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		79 interactors: ABHD17A ADAMTSL4 ALG13 BLZF1 C1orf94 CCDC33 CHIC2 CHRD CRACR2A DUSP22 EFEMP2 FAM154A FHL5 GATA1 GP9 GRN HOXD3 HSFY1 IKZF2 KDM1A KRT31 KRT38 KRT40 KRT81 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP12-4 KRTAP26-1 KRTAP3-2 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE3E LCE4A LGALS13 LIMS1 LNX2 LPXN MDFI MGAT5B N4BP2L2 NOTCH2NL PBX1 PBX2 PCSK5 PDCD6IP PIK3R1 PITX2 PKNOX1 PLSCR1 PLSCR4 PRMT6 PRRC2B RAB33A RBPMS RGS17 RGS20 SDCBP SPRY1 SUV39H1 TBC1D10C TCF3 TRAF1 TRAPPC6A TRIM42 TRIP6 ZZZ3	5 interactors: HOXA1 MAP2K4 MAP2K7 MAPK14 MAPK8
Entrez ID		3198	56940
HPRD ID		00843	13255
Ensembl ID		ENSG00000105991	ENSG00000112679
Uniprot IDs		P49639	Q9NRW4
PDB IDs			1WRM
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Embryo Development Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Pattern Specification Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of Signal Transduction Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Positive Regulation Of Gene Expression Epidermis Development Positive Regulation Of Extracellular Vesicular Exosome Assembly Regulation Of DNA Binding Regulation Of Protein Import Into Nucleus Regulation Of Transcription Factor Import Into Nucleus Regulation Of Signaling Regulation Of Extracellular Vesicular Exosome Assembly Regulation Of Protein Localization To Nucleus Developmental Process Regulation Of Nucleocytoplasmic Transport Negative Regulation Of Signal Transduction Biosynthetic Process RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Negative Regulation Of DNA Binding Keratinization Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Signaling Epidermal Cell Differentiation Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Phospholipid Scrambling Regulation Of Intracellular Protein Transport Gene Expression Regulation Of Cell Proliferation Positive Regulation Of Cellular Metabolic Process Blood Coagulation	Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Toll-like Receptor Signaling Pathway Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Positive Regulation Of Innate Immune Response MAPK Cascade Regulation Of Innate Immune Response Signal Transduction By Phosphorylation Cellular Response To Sorbitol Response To Abiotic Stimulus JNK Cascade Response To Radiation Immune Response-regulating Signaling Pathway Activation Of MAPK Activity Positive Regulation Of Immune Response Cellular Response To Organic Substance Innate Immune Response Positive Regulation Of MAP Kinase Activity Fc-epsilon Receptor Signaling Pathway Regulation Of Immune Response Positive Regulation Of Immune System Process Peptidyl-amino Acid Modification Apoptotic Process Fc Receptor Signaling Pathway Response To Organic Substance Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Programmed Cell Death Regulation Of MAP Kinase Activity Cell Death Death Activation Of JUN Kinase Activity Response To Light Stimulus Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Signal Transduction Immune Response Regulation Of Immune System Process
Tagcloud ?		divergence embryo embryos exert gsc illustrate introduced liganded ligands malformations microinjection nevertheless pleiotropic possess posterior rar reporter responsive responsiveness retinoid retinoids rxr selective striking vertebrate vertebrates xenopus xlim zebrafish	adnexal attributable bead bisulfite chip chlamydophila coefficient cp cxcl6 dmgs doxy doxycycline emzl extranodal hypermethylated hypomethylated illumina infinium irak1 korean marginal nonresponders ocular psittaci pyrosequencing ranking responder spearman statuses
Tagcloud (Difference) ?		divergence embryo embryos exert gsc illustrate introduced liganded ligands malformations microinjection nevertheless pleiotropic possess posterior rar reporter responsive responsiveness retinoid retinoids rxr selective striking vertebrate vertebrates xenopus xlim zebrafish	adnexal attributable bead bisulfite chip chlamydophila coefficient cp cxcl6 dmgs doxy doxycycline emzl extranodal hypermethylated hypomethylated illumina infinium irak1 korean marginal nonresponders ocular psittaci pyrosequencing ranking responder spearman statuses
Tagcloud (Intersection) ?