PCBP2 and YBX3

Number of citations of the paper that reports this interaction (PMID 8871564)
21

Data Source:
HPRD (two hybrid)

		PCBP2	YBX3
Gene Name		poly(rC) binding protein 2	Y box binding protein 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Focal Adhesion Membrane Ribonucleoprotein Complex Extracellular Vesicular Exosome	Nucleus Cytoplasm Polysome Tight Junction Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding RNA Binding Protein Binding Enzyme Binding Ubiquitin Protein Ligase Binding Poly(A) RNA Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Double-stranded DNA Binding Single-stranded DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity MRNA 3'-UTR Binding Rho GTPase Binding Poly(A) RNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Splicing Gene Expression MRNA Metabolic Process Negative Regulation Of Type I Interferon Production Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Innate Immune Response Negative Regulation Of Defense Response To Virus Defense Response To Virus	Negative Regulation Of Transcription From RNA Polymerase II Promoter In Utero Embryonic Development Transcription, DNA-templated Spermatogenesis Male Gonad Development Response To Cold Fertilization Positive Regulation Of Organ Growth Negative Regulation Of Skeletal Muscle Tissue Development Negative Regulation Of Necroptotic Process 3'-UTR-mediated MRNA Stabilization Cellular Response To Tumor Necrosis Factor Cellular Hyperosmotic Response Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress Positive Regulation Of Cytoplasmic Translation
Pathways		RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing Negative regulators of RIG-I/MDA5 signaling mRNA Splicing - Major Pathway Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		25 interactors: BARD1 CASK CNBP FLNA HMGA1 HMGA2 HNRNPD HNRNPK HNRNPL NKAP PABPC1 PAXIP1 PCBP1 PRPF40A PTBP1 QKI SF3B2 SLU7 SNRPA SRSF3 SRSF7 WDR77 WDR83 YBX1 YBX3	8 interactors: GSK3B IL7R MAPK1 NFYB PCBP2 RALA TJP1 VEGFA
Entrez ID		5094	8531
HPRD ID		03129	10347
Ensembl ID		ENSG00000197111	ENSG00000060138
Uniprot IDs		B4DXP5 F8VZX2 G3V0E8 Q15366	P16989
PDB IDs		2AXY 2JZX 2P2R 2PQU 2PY9
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process RNA Processing Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of MRNA Stability Regulation Of RNA Stability Positive Regulation Of Gene Expression Posttranscriptional Regulation Of Gene Expression Regulation Of Gene Expression Regulation Of RNA Metabolic Process Transcription, DNA-templated Oncogene-induced Cell Senescence Positive Regulation Of Macromolecule Biosynthetic Process Metabolic Process RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of MRNA Processing MRNA Stabilization Regulation Of Nitrogen Compound Metabolic Process Senescence-associated Heterochromatin Focus Assembly Negative Regulation Of Gene Expression Positive Regulation Of Cellular Senescence Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Cell Aging Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Translation Heterochromatin Assembly Biosynthetic Process MRNA 3'-end Processing Heterochromatin Organization Positive Regulation Of Cellular Metabolic Process Regulation Of MRNA 3'-end Processing Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Regulation Of Translation	Response To External Stimulus Cellular Response To Organic Substance Regulation Of Cell Size Positive Regulation Of Peptidyl-threonine Phosphorylation Cellular Response To Growth Factor Stimulus Regulation Of Immune System Process Chemotaxis Response To Growth Factor Response To Organic Substance Neurotrophin TRK Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cellular Response To Heat Regulation Of Vascular Permeability Neurotrophin Signaling Pathway Positive Regulation Of Gene Expression Response To Biotic Stimulus Positive Regulation Of Axon Extension Positive Regulation Of Cell Projection Organization Regulation Of MAP Kinase Activity Positive Regulation Of Cellular Component Biogenesis Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Cellular Component Size Positive Regulation Of Cell-matrix Adhesion Apoptotic Process Positive Regulation Of Cell Adhesion Programmed Cell Death Regulation Of Vesicle-mediated Transport Cellular Response To Heat Regulation Of Cellular Localization Axon Guidance Cell Death Death Cell Morphogenesis Regulation Of Axon Extension Regulation Of Cellular Amino Acid Metabolic Process Response To Abiotic Stimulus Immune System Process Positive Regulation Of Axonogenesis Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Protein Kinase D Signaling Cell-cell Signaling Involved In Cell-cell Junction Organization Basophil Chemotaxis Regulation Of Cell Projection Organization Locomotion Anatomical Structure Morphogenesis Regulation Of Cellular Ketone Metabolic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway In Utero Embryonic Development Immune Response Regulation Of Peptidyl-serine Phosphorylation
Tagcloud ?		9b aip4 atg5 clue coronaviruses cov depended dynamin etiologic evade evades fission havoc hect illustrates localizes manipulates mavs mitochondria orf outbreak proteasomal sars signalosome traf traf3 triggering uncovered usurping	absent alleles aml atlas australasian bank box conjunction enrichment epigenetic frequently hnrnpr hypermethylation leukemic marks matr3 promoter sf3a1 sf3b1 silence silico somatic splicing srsf2 suppressing u2af1 u937 zfr zrsr2
Tagcloud (Difference) ?		9b aip4 atg5 clue coronaviruses cov depended dynamin etiologic evade evades fission havoc hect illustrates localizes manipulates mavs mitochondria orf outbreak proteasomal sars signalosome traf traf3 triggering uncovered usurping	absent alleles aml atlas australasian bank box conjunction enrichment epigenetic frequently hnrnpr hypermethylation leukemic marks matr3 promoter sf3a1 sf3b1 silence silico somatic splicing srsf2 suppressing u2af1 u937 zfr zrsr2
Tagcloud (Intersection) ?