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SRI and PDE4C
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
SRI
PDE4C
Gene Name
sorcin
phosphodiesterase 4C, cAMP-specific
Image
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Mitochondrion
Endoplasmic Reticulum Membrane
Smooth Endoplasmic Reticulum
Cytosol
Membrane
Sarcoplasmic Reticulum
Z Disc
T-tubule
Sarcoplasmic Reticulum Membrane
Chromaffin Granule Membrane
Axon Terminus
Dendritic Spine Neck
Extracellular Vesicular Exosome
Extracellular Space
Cytosol
Primary Cilium
Molecular Function
Protease Binding
Calcium-dependent Cysteine-type Endopeptidase Activity
Receptor Binding
Calcium Channel Regulator Activity
Calcium Ion Binding
Protein Binding
Ion Channel Binding
Protein Heterodimerization Activity
Repressing Transcription Factor Binding
3',5'-cyclic-AMP Phosphodiesterase Activity
Metal Ion Binding
Biological Process
Action Potential
Proteolysis
Transport
Calcium Ion Transport
Intracellular Sequestering Of Iron Ion
Regulation Of Striated Muscle Contraction
Signal Transduction
Heart Development
Muscle Organ Development
Regulation Of Heart Contraction
Negative Regulation Of Heart Rate
Regulation Of Cell Communication By Electrical Coupling
Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum
Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Cytoplasmic Sequestering Of Transcription Factor
Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Regulation Of Calcium Ion Transport
Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Regulation Of Cardiac Muscle Cell Contraction
Regulation Of Relaxation Of Muscle
Regulation Of High Voltage-gated Calcium Channel Activity
Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction
Negative Regulation Of Transcription Regulatory Region DNA Binding
CAMP Catabolic Process
Signal Transduction
Pathways
Ion channel transport
Stimuli-sensing channels
Signaling by GPCR
GPCR downstream signaling
G alpha (s) signalling events
Opioid Signalling
DARPP-32 events
Drugs
Diseases
GWAS
Protein-Protein Interactions
18 interactors:
ALG2
ANXA11
ANXA7
CACNA1C
CACNA1S
CALCOCO2
GCA
NRAS
PDE4C
PRR13
PSEN2
RYR2
SHBG
SMAD2
SNCA
SRPK2
STAT3
TCF12
1 interactors:
SRI
Entrez ID
6717
5143
HPRD ID
01680
02529
Ensembl ID
ENSG00000075142
ENSG00000105650
Uniprot IDs
B4DHQ6
B4DKK2
C9J0K6
P30626
O43849
P78505
Q08493
Q32MM7
Q7KYS4
PDB IDs
1JUO
2JC2
1LXU
2QYM
Enriched GO Terms of Interacting Partners
?
Response To Calcium Ion
Behavior
Response To Metal Ion
Developmental Process
Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Muscle Contraction
Response To Inorganic Substance
Anatomical Structure Morphogenesis
Response To Stimulus
Regulation Of Calcium Ion Transport Into Cytosol
Anatomical Structure Development
Striated Muscle Contraction
Enzyme Linked Receptor Protein Signaling Pathway
Cell Communication By Electrical Coupling Involved In Cardiac Conduction
Muscle System Process
Action Potential
Regulation Of Membrane Potential
Cell Differentiation
Cellular Response To Growth Factor Stimulus
Cell Communication By Electrical Coupling
Cellular Calcium Ion Homeostasis
Response To Growth Factor
Calcium Ion Transport
Calcium Ion Homeostasis
Cellular Response To Epinephrine Stimulus
Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion
Response To Epinephrine
Membrane Depolarization
Response To Abiotic Stimulus
Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling
Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum
Axon Guidance
Cellular Response To Catecholamine Stimulus
Cellular Metal Ion Homeostasis
Cell Development
Regulation Of Ion Homeostasis
Regulation Of Synaptic Plasticity
Response To Organic Substance
Intracellular Signal Transduction
Regulation Of Long-term Neuronal Synaptic Plasticity
Immune Response
Cellular Cation Homeostasis
System Development
Cellular Ion Homeostasis
Calcium Ion Import
Single-organism Behavior
Membrane Depolarization During Action Potential
Positive Regulation Of Metabolic Process
Chemical Homeostasis
Metal Ion Homeostasis
Intracellular Sequestering Of Iron Ion
Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction
Regulation Of High Voltage-gated Calcium Channel Activity
Regulation Of Relaxation Of Muscle
Negative Regulation Of Heart Rate
Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Sequestering Of Metal Ion
Regulation Of Cell Communication By Electrical Coupling
Negative Regulation Of Transcription Regulatory Region DNA Binding
Negative Regulation Of Calcium Ion Transmembrane Transporter Activity
Negative Regulation Of Cation Channel Activity
Regulation Of Voltage-gated Calcium Channel Activity
Cytoplasmic Sequestering Of Transcription Factor
Negative Regulation Of Heart Contraction
Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Regulation Of Transcription Regulatory Region DNA Binding
Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum
Cytoplasmic Sequestering Of Protein
Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
Positive Regulation Of Calcium Ion Transport Into Cytosol
Negative Regulation Of Transporter Activity
Negative Regulation Of Calcium Ion Transport
Regulation Of Cardiac Muscle Cell Contraction
Negative Regulation Of DNA Binding
Negative Regulation Of Ion Transmembrane Transport
Negative Regulation Of Transcription Factor Import Into Nucleus
Negative Regulation Of Transmembrane Transport
Regulation Of Calcium Ion Transmembrane Transporter Activity
Regulation Of Calcium Ion Transmembrane Transport
Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Positive Regulation Of Insulin Secretion
Negative Regulation Of Protein Import Into Nucleus
Regulation Of Heart Rate
Regulation Of Cardiac Muscle Contraction
Regulation Of Cation Channel Activity
Positive Regulation Of Peptide Hormone Secretion
Regulation Of Calcium Ion Transport Into Cytosol
Positive Regulation Of Peptide Secretion
Negative Regulation Of Protein Localization To Nucleus
Cellular Iron Ion Homeostasis
Regulation Of DNA Binding
Regulation Of Striated Muscle Contraction
Action Potential
Negative Regulation Of Intracellular Protein Transport
Regulation Of Transcription Factor Import Into Nucleus
Positive Regulation Of Calcium Ion Transport
Negative Regulation Of Ion Transport
Negative Regulation Of Binding
Tagcloud
?
aza1r
cat
crabp
defective
differentiation
embryonal
hoxa
indirectly
inducer
initiating
luc
mesenchymal
morphological
multistage
parental
pcc4
ra
rar
rars
retinoic
retinoid
ro
rxr
rxre
selective
sr11
tk
transactivates
unable
Tagcloud (Difference)
?
aza1r
cat
crabp
defective
differentiation
embryonal
hoxa
indirectly
inducer
initiating
luc
mesenchymal
morphological
multistage
parental
pcc4
ra
rar
rars
retinoic
retinoid
ro
rxr
rxre
selective
sr11
tk
transactivates
unable
Tagcloud (Intersection)
?