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LOX and HIST1H1B
Number of citations of the paper that reports this interaction (PMID
12686141
)
7
Data Source:
HPRD
(in vitro)
LOX
HIST1H1B
Gene Name
lysyl oxidase
histone cluster 1, H1b
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Region
Proteinaceous Extracellular Matrix
Collagen Trimer
Extracellular Space
Nucleus
Nucleosome
Nuclear Chromatin
Nuclear Heterochromatin
Extracellular Vesicular Exosome
Molecular Function
Protein-lysine 6-oxidase Activity
Copper Ion Binding
Protein Binding
Chromatin DNA Binding
Histone Deacetylase Binding
Poly(A) RNA Binding
Biological Process
Blood Vessel Development
Cellular Protein Modification Process
Extracellular Matrix Organization
Collagen Fibril Organization
Lung Development
Wound Healing
Response To Drug
Elastic Fiber Assembly
Response To Steroid Hormone
Oxidation-reduction Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Chromatin Organization
Nucleosome Assembly
Positive Regulation Of Cell Growth
Protein Stabilization
Positive Regulation Of Histone H3-K9 Methylation
Establishment Of Protein Localization To Chromatin
Pathways
Collagen formation
Crosslinking of collagen fibrils
Elastic fibre formation
Assembly of collagen fibrils and other multimeric structures
DNA Damage/Telomere Stress Induced Senescence
Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Activation of DNA fragmentation factor
Apoptosis induced DNA fragmentation
Cellular Senescence
Programmed Cell Death
Apoptotic execution phase
Drugs
Diseases
GWAS
Thiazide-induced adverse metabolic effects in hypertensive patients (
23400010
)
Protein-Protein Interactions
7 interactors:
DHDDS
DPT
ELN
HIST1H1A
HIST1H1B
HIST1H2BJ
HIST2H2BE
26 interactors:
CBX5
CCNA1
CCNA2
CCNB1
CCNE1
CDK1
CDK2
CDK5
CDKN1A
CDKN1B
EHMT2
IRAK4
KAT2A
KAT2B
L3MBTL1
LOX
MELK
MLLT1
NSD1
PRKCA
PRKCB
PRKCD
PRKCZ
RPS6KA5
SERPINH1
SIRT1
Entrez ID
4015
3009
HPRD ID
01087
00821
Ensembl ID
ENSG00000113083
ENSG00000184357
Uniprot IDs
B7ZAJ4
D0PNI2
P28300
P16401
PDB IDs
2FE2
2RHI
Enriched GO Terms of Interacting Partners
?
Nucleosome Assembly
Chromatin Assembly
Nucleosome Organization
Chromatin Assembly Or Disassembly
Protein-DNA Complex Assembly
DNA Packaging
DNA Conformation Change
Innate Immune Response In Mucosa
Cellular Macromolecular Complex Assembly
Antibacterial Humoral Response
Chromatin Organization
Antimicrobial Humoral Response
Mucosal Immune Response
Cellular Component Assembly
Chromosome Organization
Protein Complex Assembly
Defense Response To Gram-positive Bacterium
Organelle Organization
Defense Response To Bacterium
Dolichyl Diphosphate Biosynthetic Process
Establishment Of Protein Localization To Chromatin
Humoral Immune Response
Protein Localization To Chromatin
Positive Regulation Of Histone H3-K9 Methylation
Stress Fiber Assembly
Extracellular Matrix Organization
Extracellular Structure Organization
Response To Bacterium
Protein Localization To Chromosome
Positive Regulation Of Histone Methylation
Regulation Of Protein Kinase Activity
Regulation Of Kinase Activity
Regulation Of Protein Phosphorylation
Histone Modification
Peptidyl-amino Acid Modification
Chromatin Modification
Regulation Of Phosphorylation
Regulation Of Cellular Protein Metabolic Process
Cell Cycle
Regulation Of Cell Cycle
Regulation Of Phosphorus Metabolic Process
Regulation Of Protein Metabolic Process
Chromatin Organization
Histone Phosphorylation
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Regulation Of Nitrogen Compound Metabolic Process
Cellular Protein Modification Process
Regulation Of Mitotic Cell Cycle
Cell Cycle Process
Negative Regulation Of Protein Phosphorylation
Negative Regulation Of Cellular Metabolic Process
G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle Process
Regulation Of Gene Expression
Mitotic Cell Cycle
Chromosome Organization
Regulation Of Catalytic Activity
Negative Regulation Of Phosphorylation
Protein Phosphorylation
G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Cellular Protein Metabolic Process
Response To Stress
Response To Organic Substance
Positive Regulation Of Cellular Metabolic Process
Negative Regulation Of Protein Metabolic Process
Protein Metabolic Process
Response To Wounding
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Cellular Protein Metabolic Process
Peptidyl-threonine Phosphorylation
Peptidyl-serine Phosphorylation
Regulation Of RNA Metabolic Process
Negative Regulation Of Protein Kinase Activity
Regulation Of Metabolic Process
Regulation Of Insulin Receptor Signaling Pathway
Negative Regulation Of Kinase Activity
Positive Regulation Of Cell Proliferation
Negative Regulation Of Protein Serine/threonine Kinase Activity
Wound Healing
Tagcloud
?
aldh1a1
anxa1
bcar1
cldn1
crmp1
endpoint
folr1
foxm1
il12rb2
il7r
inconclusive
kiaa1524
mcm7
mta1
mtdh
ncoa3
ndrg2
nedd9
nes
overview
pbk
ppm1d
principally
prognostication
qualifying
slc7a5
sqstm1
warranted
wnt1
Tagcloud (Difference)
?
aldh1a1
anxa1
bcar1
cldn1
crmp1
endpoint
folr1
foxm1
il12rb2
il7r
inconclusive
kiaa1524
mcm7
mta1
mtdh
ncoa3
ndrg2
nedd9
nes
overview
pbk
ppm1d
principally
prognostication
qualifying
slc7a5
sqstm1
warranted
wnt1
Tagcloud (Intersection)
?